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Enhanced Sampling and Calibration Procedures for the Analysis of Residual Oxygen in Nitrogen Purged Pharmaceutical Packaging by GC-TCD

Format: PDF file | Document type: White / Technical Paper

The classic Modified Atmosphere Packaging (MAP) application, in the pharmaceutical industry, uses medical grade nitrogen to purge atmospheric oxygen and has been applied to many systems including containers equipped with septum capped closures, pressurised gas cans, blister packs, glass snap-ampoules, foil/plastic sachets, infusion bags and medical devices. This paper focuses on an enhanced approach to sampling and calibration for the determination of residual oxygen by GC-TCD.