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Headlines > Preclinical Research

Envigo adding non-animal tech ahead of new regulations

20-Mar-2017 - Envigo is developing new In vitro tests in advance of the Comprehensive In Vitro Proarrhythmia Assay (CiPA) recommendations expected at the end of the year.

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Charles River to pay $1.8m to settle overbilling claims

16-Mar-2017 - The US Justice Department has announced Charles River Laboratories International Inc. will pay the US government $1.8m to settle claims that it violated the False Claims Act.

Heptares, Daiichi Sankyo to develop small molecules for pain treatment

15-Mar-2017 - Heptares Therapeutics has entered into a drug discovery and licensing agreement with Daiichi Sankyo – providing further validation of the company’s structure-based drug design approach, says CEO.

Cytel: model-informed drug development expanding area of focus

14-Mar-2017 - Cytel Inc. has established a dedicated quantitative pharmacology and pharmacometrics team to meet an increasing demand for model-informed drug development from biopharma clients.

Charles River re-ups Chiesi drug discovery contract

13-Mar-2017 - Charles River Laboratories has extended its integrated respiratory program with Chiesi Farmaceutici, through which it identifies and tests candidates for preclinical development.

SRI secures $90m BARDA contract

13-Mar-2017 - SRI International will advance compounds with the potential to treat persons exposed to biological, radiation, nuclear, and chemical agents – in a deal worth up to $90m.

News in brief

Certara expands PBPK simulator availability

09-Mar-2017 - Certara has developed a new licensing approach, which provides smaller organizations access to its physiologically-based pharmacokinetic (PBPK) modeling and simulation platform.

CRO insourcing to gain momentum, says NovAliX

09-Mar-2017 - NovAliX has signed an insourcing agreement with UCB Biopharma, a model that the CRO says “energizes scientific organization” and offers "significant" cost advantages. 

News in brief

Cerveau tapped for Alzheimer's research

07-Mar-2017 - Cerveau has signed a research agreement through which it will supply its early-stage imaging agent to assess the stages of Alzheimer’s disease and other neurodegenerative diseases.

WuXi subsidiary HD to use Irish cell-based assays to monitor Mitochondria

06-Mar-2017 - Irish Luxcel will grant access to its consumable in vitro cell toxicity tests to Shanghai-based CRO HD Biosciences to help reduce the risk of post-market drug withdrawal.

Preclinical CRO PharmOptima joins GBG research consortium

02-Mar-2017 - Genesis Biotechnology Group (GBG) has acquired the preclinical CRO PharmOptima in order to provide customers with a single point-of-contact throughout their drug development programs.

Metrion ion channel CRO teams up with HTS specialist Assay.Works

01-Mar-2017 - Metrion has partnered with Assay.Works for an exchange of ion channels and high-throughput screening (HTS) services for drug discovery.

GBSI report outlines steps to improve preclinical research reproducibility

27-Feb-2017 - The Global Biological Standards Institute (GBSI) has outlined an action plan after finding the frequency of irreproducible preclinical research exceeds 50% – costing the US nearly $28bn.

Envigo thyroid hormone assay meets OECD guidelines

23-Feb-2017 - Envigo has developed and validated an analytical method to evaluate the potential effects of thyroid hormone levels in rat F1 offspring.

Evotec taps into Oxford innovation through £13m grant scheme

22-Feb-2017 - Dubbed LAB282, the £13m (€15M) Oxford University drug discovery program with Evotec has announced two grant winners and a second set of awards of up to £250,000.

Almac Discovery and RCSI enter research collaboration

15-Feb-2017 - Almac Discovery and the Royal College of Surgeons in Ireland (RCSI) and have announced a research collaboration aimed at understanding how to target therapy-resistant cancer tumors.

Report: study design flaws slowing Parkinson's research

13-Feb-2017 - Researchers need to design more translationally relevant animal studies to improve the potential for success in human clinical trials, according a recent report.

Mouse model program looks to speed drug discovery

09-Feb-2017 - Taconic Biosciences has launched a new program to improve access to its cryopreserved mouse models.

AMRI gains new drug discovery tech through strategic alliance

08-Feb-2017 - AMRI has entered an alliance through which the global contract research and manufacturing organization will gain access to "new avenues of drug discovery."

Janssen to access ChemDiv discovery chemistry platform

02-Feb-2017 - ChemDiv is providing Janssen Research & Development with access to its small molecule discovery platform resources as part of a hit identification collaboration.

Sekisui XenoTech adds new test systems to service offerings

01-Feb-2017 - Sekisui XenoTech has added new dermal subcellular fraction test systems to its contract research services.

News in brief

Evotec's new UK ADMET purchase Cyprotex completes integration move

01-Feb-2017 - Cyprotex is now wholly owned by Evotec and has finished moving its operations into a facility at the BioCity BioHub in Cheshire, UK.

PEOPLE ON THE MOVE

Outsourcing-Pharma's Hiring and Firing Roundup January '17

31-Jan-2017 - Outsourcing-Pharma presents this month's round up of who is moving where in the contract research and manufacturing industry.

Enteris to work on Sanofi oral type 2 diabetes candidate & metabolic peptide for Nordic Bioscience

Sanofi and Nordic Bioscience deals ‘validate’ oral delivery tech, Enteris

25-Jan-2017 - Enteris Biopharma has secured two deals in as many days to use its excipient-based platform to enhance delivery of preclinical peptide candidates.

Evotec and Asahi Kasei up drug discovery collaboration

23-Jan-2017 - German CRO Evotec says it will invest in its staff and infrastructure to help service a drug discovery deal with Japan’s Asahi Kasei Pharma.

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