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ESA Biosciences' HPLC detector optimised for polymer analysis

By Wai Lang Chu , 18-Apr-2006

ESA Biosciences make available its HPLC detection tool that is designed for laboratories that use THF (tetrahydrofuran) as a component in chromatographic separations and sample analyses.

The Corona Plus is particularly designed for polymer laboratories, which will be able to benefit from the all-in-one performance benefits that refractive index, low wavelength UV and evaporative light scattering (ELS) detector methods lack.

THF is a commonly used solvent in a number of industries where it is widely used for solubilising and separating various types of polymers.

Its performance provides ten times the sensitivity of ELS, a broad range of over four orders of magnitude, more consistent response factors independent of chemical structure, delivering for the first time to HPLC users almost complete universality.

Charged aerosol detection is a robust HPLC detection technology that delivers advanced capabilities of interest to every HPLC user-lab.

In addition, the HPLC column eluent is nebulised and the resulting droplets dry are evaporated at ambient temperature producing analyte particles.

A second stream of gas is positively charged as it passes a high-voltage, platinum corona wire.

The charged gas collides with and transfers charges to the opposing stream of analyte particles.

A negatively charged, low-voltage ion trap removes high-mobility particles while analyte particles transfer their charges to a collector.

The charge transferred to the collector is in direct proportion to analyte mass.

Further details of the Corona Plus are available on ESA Biosciences' >website.