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How Sponsors and CROs Benefit From EDC Efficiencies - Merge Healthcare

01-Apr-2015 - Intense competition in the prescription drug market is driving pharmaceutical companies to expedite their drug discovery and development processes. Pharmaceutical companies understand the value of being the first to bring a new drug to market, and it is this knowledge...
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The in-PharmaTechnologist Anti-counterfeiting Forum - William Reed Business Media

18-Mar-2015 - Drug counterfeiting: a pharmaceutical industry problemCounterfeiters rely on two things: poorly secured pharmaceutical supply chains; and the fact people want to pay less for less for drugs.Most fake erectile dysfunction drugs seized in Europe contain at least some trace of...
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Lyophilisation Parameters to Eliminate Surface Cracks - Patheon Inc

09-Mar-2015 - Learn about the correlation between lyophilisation cycle parameters and cake morphology in a biosimilar product. The presence of cracks on the surface of the lyophilized product can be considered a defect in particular for some markets. See how analytical methods...
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The whole blood assay: Detection of broad spectrum of pyrogens & examples of medical device testing - Merck Millipore microbial industry

09-Mar-2015 - Pyrogens in pharmaceuticals, medical devices, biotherapeutics and cosmetics can cause fevers in humans and are potentially life-threatening. Yet standard pyrogen detection methods have drawbacks. The Limulus Amoebocyte Lysate (LAL) test only identifies endotoxins, while the rabbit pyrogen test (RPT) endangers...
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Meaningful Metrics – A CMO Perspective - Patheon Inc

05-Jan-2015 - Learn about the roles of sponsors and their contract manufacturing organization (CMO) partners regarding metrics, what metrics to measure, how to manage data, effective communications and ownership, and ways to improve your metrics. To optimize the value of metrics, it...
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Bioavailability market dynamics - William Reed Business Media

30-Sep-2014 - How healthy is demand for bioavailability enhancement services? Is the growth of the generics sector driving the market or do innovative pharma firms determine the type of solubility solutions that are available.When biopharmaceutical are injected they are 100% bioavailable, but...
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A brief history of bioavailability - William Reed Business Media

30-Sep-2014 - Tablets have been around for almost 200 years. In this presentation we trace the history of their development, from the accidental invention of the sustained release pill through to the latest breakthroughs in bioavailability enhancement, this talk will take us...
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MARKEN DELIVERS MEDICINE TO HELP SAVE A CHILD’S LIFE - Marken

26-Sep-2014 - A child in Australia is critically ill and in immediate need of a drug available only in the United Kingdom. Marken’s team of experts uses its immediate access to validated packaging and airline contacts to secure a direct flight. Through...
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Viral-Challenge Studies: Regulatory Requirements - SGS

15-Sep-2014 - The use of viral-challenge studies as POC studies is gaining wider acceptance. This approach accelerates the selection of a safe and effective dose and dosing regimen for a new antiviral drug/ vaccine as it allows for early detec­tion of efficacy....
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7 Common Myths about QP Training Debunked : A Guide for Senior Managers - Reading Scientific Services Limited

11-Sep-2014 - The role of the Qualified Person (QP) in the pharmaceutical industry is mandated by law (Directive 2001/83/EC, Directive 2001/20/EC, UK SI 2012/1916, UK SI 2004/103). Every holder of a relevant Manufacturers Authorisation (human and veterinary) must have at least one...
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Learn the risk factors of metabolic syndrome and the role central labs play in aiding its detection - ACM Global Central Laboratory

17-Jun-2014 - Metabolic syndrome, a serious condition impacting adults and children in all genders, races and ethnicities, can lead to fatal outcomes if not detected and treated. The key risk factors of metabolic syndrome were identified approximately 250 years ago. However, there...
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Are there Any Markets left to Emerge? - World Courier

02-Jun-2014 - North America, Western Europe and—to a lesser extent—Australasia once served as prime locations for the majority of research. But these Western markets are approaching saturation, which has led to a lack of naive patients who are available and willing to...
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Excipients for Multilayer Tablets - JRS PHARMA LP

07-May-2014 - Multi-layered tablets bring together differently formulated powder mixtures, which typically contain different APIs, into a single tablet with two or more layers. They offer benefits for overcoming API-API interactions and stability issues, tailoring dissolution profiles, and bringing brand recognition to...
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Fast and Flexible – Early Phase Manufacturing - Patheon Inc

05-May-2014 - Early-stage manufacturers of oral solid dosage forms need to be fast and flexible to generate development pathways that can cope with variable API characteristics as well as highly potent molecules. Technology, risk assessment, Quality by Design and scale up are...
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Meeting the challenges of complex drug substances - Vetter Pharma International GmbH

15-Apr-2014 - Realizing the full potential of an injectable drug compound is no small task. In the months and years that lead from the discovery phase to the rigorous demands of a commercial launch, unexpected scientific and technical challenges can slow development...
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White Paper: Model-Based Drug Development - SGS Life Science Services

14-Apr-2014 - In this white paper learn how MBDD can help you make better drug development decisions through the use of mathematical models. Read how such models can be applied to population pharmacokinetics, dose-response characterization, and pediatrics. 
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Dow AFFINISOL™ polymers for Solubility Enhancement - Dow Pharma & Food Solutions

12-Mar-2014 - Dow’s AFFINISOL™ line of excipients include AFFINISOL™ HMPCAS for spray drying applications and AFFINISOL™ HPMC for hot melt extrusion (HME) applications. Hypromellose acetate succinate (HPMCAS) has proven effective at producing stable amorphous solid dispersions for poorly soluble APIs. We will highlight: •...
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How glass-forming polymers improve bioavailability / Enhanced oral bioavailability with Soluplus® – case study - BASF SE

12-Mar-2014 - How glass-forming polymers improve bioavailabilityPolymers are essential components of oral solid dosage forms and used as binders, disintegrants or coatings. Given the increase in poorly water-soluble drugs, not only well-known but also specifically designed polymers (e.g. Soluplus®) can be used...
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Role of excipients in design of solid amorphous drug dispersions for delivery of poorly water-soluble drugs - Ashland

10-Mar-2014 - Most new drug candidates suffer from poor water- solubility leading to rate limiting dissolution, slow absorption and limited bioavailability. Solid amorphous drug dispersions are most commonly used improve bioavailability by enhancing drug solubility. The selection of the right solid dispersion...
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Controlled Release and Bioavailability Enhancement -

28-Oct-2013 - Metrics provides product development that leverages proprietary pharmaceutical technologies in the areas of: •    Customized Controlled Release Drug Delivery •    Bioavailability Enhancement •    Taste Masking (liquid and solid presentations)When applied appropriately, these technologies can deliver therapeutic and convenience benefits to...

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