Albumedix tech key to Chinese efforts to develop once-a-week diabetes drug

By Gareth Macdonald

- Last updated on GMT

iStock/designer491
iStock/designer491

Related tags Food and drug administration Pharmacology Us food and drug administration

Recombinant albumin supplier Albumedix will help Hebei Changshan Biochem Pharma develop a once-a-week diabetes treatment.

The collaboration – financial terms of which were not disclosed – will use Albumedix’ albumin to extend the half-life of a modified glucagon-like-peptide albumin conjugate called Albenatide that is being developed for the Chinese market.

Albenatide was developed by Changshan and partner ConjuChem using the latter firm’s drug affinity complex (DAC) technology. The idea is to prevent therapeutic proteins being degraded or rapidly excreted by attaching albumin.

Albumedix will be supplying its recombinant albumin to Changshan for remaining clinical development and for commercial production of the product if it goes on to be approved for the treatment of type II diabetes in China.

Albumedix COO Svend Erik Licht told us “The Albenatide project is currently in phase I and expected to move into Phase II later this year.”

He added that: “The project has a fast-track (Green Channel) approval in China, which has accelerated the regulatory approval process for Hebei Changsan Biochem Pharma significantly​.” 

Albumedix’ albumin technology – known as its Veltis platform – is already being used in number of commercial products.

For example, CSL Behring is using it to extend the half-life of its haemophilia B treatment Idelvion, which was approved by the US Food and Drug Administration (FDA) and European Medicines Agency (EMA) in March.

Similarly, GSK’s type II diabetes drug Eperzan​ (albiglutide) – which is known as Tanzeum​ in the US – also uses the Veltis technology.

Related news

Show more

Related products

show more

Increasing the Bioavailability of Oncology Drugs

Increasing the Bioavailability of Oncology Drugs

Content provided by Lonza Small Molecules | 13-Nov-2023 | White Paper

Oral tyrosine kinase inhibitors (TKIs) are a class of cancer drugs that can be highly susceptible to issues with solubility in the gastrointestinal tract

Addressing Challenges with Clinical In-Use Testing

Addressing Challenges with Clinical In-Use Testing

Content provided by Lonza | 12-Oct-2023 | White Paper

Lonza Drug Product expert Léa Sorret PhD explores Clinical In-Use Testing of Biotherapeutics in this white paper. Léa shares her expertise and describes...

PBPK modeling that saves you time and money

PBPK modeling that saves you time and money

Content provided by Lonza Small Molecules | 09-Oct-2023 | White Paper

Understanding pharmacokinetic behaviors ahead of later-stage development means making informed decisions earlier. This enhanced capability helps your drug...

Related suppliers

Follow us

Products

View more

Webinars