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On-Demand Supplier Webinar
Antibody Drug Conjugate Development and Manufacture - Piramal
03-May-2013 -
With the recent approvals of brentuximab vedotin (Adcetris) and ado-trastuzumab emtansine (Kadcyla,T-DM1), antibody–drug conjugates (ADCs)are a rapidly growing area in oncology with great potential. Development and manufacture of ADCs can be a challenge with the requirement to handle both biologics...
Technical / white paper
ePathology Improves Data Accuracy & Study Productivity! – Amicus Study Confirms - Aperio
20-Mar-2013 -
With current glass slide methods, sharing and scoring slides within a study from one pathologist to another at a different organization or site, meant that slides had to be packed, shipped and tracked. Often the reading pathologist was required to...
Data sheet
Quantify biodistribution, enhance in vivo decisions - Molecular Imaging Inc.
04-Feb-2013 -
Non-invasive preclinical SPECT imaging of test agent biodistribution, kinetics and targeting in discovery and safety applications has key advantages over pre-existing methods including:
full 3-dimensionality with tissue and sub-tissue localization
fine kinetics, targeting, binding and clearance pathways can be examined
clinical translatability
isotope multiplexing...
Technical / white paper
Biomarkers of Toxicity Panel in Clinical Trials - ACM Global Central Lab
18-Sep-2012 -
Most drug candidates are discontinued because of induced organ toxicity and half of them owe this to liver toxicity. This issue explains why drug developers need to be aware of the latest options for liver and kidney laboratory safety testing,...
Technical / white paper
Utility of FDG PET in Drug Development - Molecular Imaging Inc.
20-Aug-2012 -
Imaging metabolism with FDG PET offers reliable and clinically translatable biomarkers for evaluation of candidate compounds.
Technical / white paper
Novel Biomarkers for Diabetic Nephropathy - Pacific Biomarkers, Inc.
18-May-2011 -
Type 2 diabetes is the major cause of end-stage renal disease. In the present decade, 30% of the predicted $1.1 trillion medical costs of dialysis world-wide will result from diabetic nephropathy. There is an unmet need for highly sensitive biomarkers...
Technical / white paper
Guiding Development of Novel Drugs - PBI
16-Mar-2011 -
Increased use of therapeutic proteins such as monoclonal antibodies, engineered proteins and other biological products has resulted in a growing number of biotherapeutic drugs. New biotherapeutic drugs bring tremendous advancement in the treatment of a number of diseases. To ensure...
On-Demand Supplier Webinar
Biomarkers of Metabolic Syndrome in Clinical Trials - PBI
11-Feb-2011 -
PBI scientists will discuss latest developments in biomarkers for metabolic syndrome. Topics: 1) Pre-analytical and analytical concerns regarding gut and incretin hormones, 2) Dysfunctional HDL biomarkers in metabolic syndrome, and 3) Kidney Injury Markers and their usefulness in diabetic nephropathy....
Technical / white paper
Reducing Dosing Errors in Preclinical GLP Infusions - Solomon Scientific
09-Feb-2011 -
The White Paper explains that the Orchesta™ Automated Infusion System from Solomon Scientific reduces dosing error opportunities by 99% in preclinical GLP infusion studies. The system is validated for GLP and Part 11 compatibility. A typical preclinical GLP infusion study...
Technical / white paper
Incretins & gastrointestinal hormones - PBI
26-Jan-2011 -
The digestion and absorption of nutrients subsequent to food intake is associated with increased secretion of multiple gastrointestinal (GI) peptides. Testing for incretins, and other GI hormones, presents numerous challenges because of their instability. The degradation and modification of gut...
Technical / white paper
Approaches to Analyzing Therapeutic Peptides and Proteins by LC-MS/MS - Covance Laboratories
14-Dec-2010 -
Covance is committed to delivering world class service, expertise and efficiency to support your drug development needs. In the attached white paper, read how Covance supports peptide and protein analysis by LC-MS/MS delivering the following benefits over the typical immunoassay....
Technical / white paper
Generate Sales Leads: Free White Paper - William Reed Business Media
02-Aug-2010 -
White papers (or technical papers) are one of the most effective ways to generate leads for your sales team and establish your company’s reputation as a thought leader. Want to know how to create an effective white paper? Download William...
Survey
Are you Asking the Right Questions? - William Reed Business Media
02-Aug-2010 -
Want to evaluate your company’s brand image or the opinion of the Outsourcing-Pharma readers on a certain topic? Want to perform a market research analysis without the hassle? Download William Reed Business Media’s survey brochure to find out how you...
Technical / white paper
Generate sales leads with a good white paper - William Reed Business Media
24-Mar-2010 -
White papers (or technical papers) are one of the most effective ways to generate leads for your sales team and improve your company’s reputation as an expert. Want to know how to create effective white papers? Download this guide now....
Technical / white paper
Why, When and How to Conduct Human 14C ADME Studies - SGS
23-Oct-2009 -
Learn about the strategies for managing the risk related to drug metabolites, and how the final 14C-human ADME studies should be conducted; includes: 3 approaches on fulfilling requirements and a “How-to” summary on conducting an ADME trial.
Technical / white paper
Discover Hidden Gems in your Clinical Development Portfolio - Exploristics
18-Sep-2009 -
Exploristics have implemented tools that use existing clinical data to identify subgroups of patients that respond to treatment. These tools can be applied at a study or portfolio level and enable an informed and pragmatic approach to development decisions. This...
Product brochure
“I Need BASi for Culex® Automated In Vivo Sampling Systems.” - BASi
02-Sep-2009 -
Rely on BASi for practical solutions to administering compounds, monitoring animals under study and sampling the full range of testing matrices with minimal human intervention. Our proprietary Culex Automated In Vivo Sampling System will collect both PK and PD data...
Technical / white paper
Combinatorial Pharmacology in Mice - BASi
20-Aug-2009 -
Innovative In Vivo Sampling InstrumentationSet up your lab from start to finish! The comprehensive BASi Microdialysis System (BMS) includes everything from start-up kits with surgical instruments and accessories, to animal containment and fraction collection. Choose a basic system or one...
On-Demand Supplier Webinar
Webinar - Meeting the Challenges of Biosimilars Characterization - Solvias AG
16-Jul-2009 -
Generic biologics offer the prospect of cheaper medicines, however exact copies of innovator biological drugs are not possible. A review of analytical requirements, challenges, and the lessons learned will be presented.
Technical / white paper
Biopharmaceutical Drug Developers topic: Detection of protein aggregation by AF4/MALS - Wyatt
02-Jul-2009 -
The formation of aggregates in biopharmaceuticals such as monoclonal antibodies (MAbs), represents a severe problem, which has also been addressed by FDA authorities recently. Particularly their potential to trigger or enhance undesirable immune responses may cause adverse clinical effects or...
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BioPharm America™ 2013—6th Annual International Partnering Conference
Boston, MA, USA / Conference
