Affymetrix introduces its new ChIP-On-Chip array product line that
its designers hope will provide drug researchers with new
whole-genome tools to assist scientists discover DNA-Protein
interactions.
British gene therapy firm Oxford Biomedica has licensed its VSV-G
viral envelope technology for gene delivery to American biotech
company VIRxSYS which hopes it can use it to successfully produce
its promising anti-HIV/AIDS product...
A new laboratory method for distinguishing pathogens from harmless
relatives has been developed by scientists in the US. The
high-throughput technique will enable the quick identification of
pathogens, which could be used for bioterror...
Agilent introduces its next generation of assay kits for its 2100
Bioanalyser Lab-on-a-Chip platform that aims to replace
labour-intensive SDS-PAGE and capillary gel electrophoresis (CGE)
methods providing faster microfluidic analyses.
Dutch life science firm PharmaCell has hired quality control
specialist Sensitech for the cold chain management of their cell
culture products, allowing it to ensure compliance with GMP
regulations.
Scientists have discovered a new way that drugs can attach
themselves to DNA, providing a crucial step forward for those who
are developing drugs to combat cancer and other diseases. The
breakthrough heralds a new way of recognising...
Swiss outsourcing company Lonza has granted biotechnology firm
Genentech a non-exclusive, worldwide license to their Glutamine
Synthetase (GS) Gene Expression System which offers better yields,
speed and stability in cell protein...
A disposable two-compartment flask bioreactor designed by Swiss
company Integra Biosciences has been shown to minimise production
costs in a new study, as opposed to cell cultivation roller bottles
which are 60 per cent more expensive.
A new easy-to-use laser microdissection system from Olympus is set
to shake up the isolation technology market by reducing sample
handling and contamination when isolating cells for downstream
analysis and making the process routine.
Sigma-Aldrich has strengthened its position in the RNAi and
cell-based assay market by signing a series of agreements in which
the life science company has acquired a minority equity stake in
Genospectra and is granted access to various...
Surmodics has announced that as a result of a collaboration with
the Donaldson Company, the first of a collection of new synthetic
nanofibrillar cell culture surfaces have been produced that will
improve cell culture, cell-based bioassays...
Pharmion and MethylGene has announced the formation of an
international licensing agreement potentially worth $272 million
(€224 million) for new class of compounds that inhibits gene
expression providing a tumour and haematological...
Beckman Coulter makes available a new workstation that automates
microarray sample preparation for gene expression studies that
offered at a lower cost than other options on the market. The
workstation is an evolution of the higher...
Sigma Aldrich has launched a new integrated lysis and affinity
purification (iLAP) column, which greatly simplifies the process of
cell lysis and histidine-tagged protein purification into one step,
allowing fast, efficient and non-denaturing...
Velocity11 has announced a new configuration of its BioCel
sample-processing platform that will allow all cell-based Elisa
procedures to become fully automated, reducing the risk of human
error, contamination and time spent on tedious...
Pfizer has announced the expansion of an existing collaboration
with Sangamo Biosciences, which will use zinc finger DNA-binding
protein (ZFP) technology to develop additional cell lines for
enhanced protein production.
The expiration of the Polymerase Chain Reaction (PCR) patent is set
to offer growth opportunities for nucleic acid purification and
amplification technologies, particularly for small companies, who
can offer tests without developing...
Affymetrix has launched its latest microarray sequencer, which
enables researchers to identify genetic variations associated with
diseases, forensics, population studies or stem cells, proving
particularly useful in drug research...
Solexa has announced the introduction of its DNA sequencing,
expression profiling and micro-RNA analysis platform designed to
generate over a billion bases of sequence per run, making it ideal
for plans to sequence the entire human...
Stratagene announces a molecular diagnostics agreement, which aims
to focus on the growing molecular diagnostics market for infectious
diseases, currently worth $6.5 billion (€5.5 billion), expanding to
$12 billion by 2010 driven...
Gentra Systems has introduced its new versaGene DNA Cell
Purification Kit, which responds to the growing need for
high-quality DNA for sensitive downstream applications. The kit
uses chemistry and column design to purify DNA with...
Researchers have developed a new laboratory technique, which allows
them to change sequences within a DNA molecule. The tool is set to
have positive implications in DNA lab-based medical diagnosis and
nanobiotechnology.
Researchers have shown how protein synthesis is targeted to certain
regions of a cell, a process crucial for the cellular motility,
which could form a basis for producing a drug that could force
tumour cells to express this protein,...
GenoID has announced a breakthrough in human papillomavirus (HPV)
testing with the first ever laboratory test kit that uses a
real-time polymerase chain reaction (real-time PCR) method to
detect all virus variants that cause cervical...
Sigma-Aldrich Fine Chemicals (SAFC) Biosciences chose the CPhI Expo
in Madrid to announce a series of updates concerning company
activity. The custom manufacturing group is currently undergoing
construction of a new US facility aimed...
Researchers have demonstrated the precise movements of an enzyme
during replication that may serve as a precursor to understanding
genetic disease caused by abnormal enzyme activity.
Scientists have described it as an achievement that will
revolutionise medicine as the first genetic "map" of human
diversity was published. The gene map, which details common
differences in the human genome, could lead...
Agilent Technologies launches its latest microarray solution for
analysing activity at regulatory regions of genomes, enabling
researchers to examine gene regulation in a more efficient and
cost-effective manner.
A new technique that adds to the effectiveness of gene therapy has
made a breakthrough after it was revealed that the method had cured
phenylketonuria (PKU) in mice.
Innovata of the UK has sold off its gene expression technology UCOE
to Celliance Corp, a wholly owned subsidiary of Serologicals, for
an undisclosed fee.
A newly discovered compound, which has revealed new links between
cell signalling pathways and cell migration, may suggest new
avenues for novel pharmaceutical therapies for treating a variety
of diseases, including cancer.
A discovery by scientists may provide a novel method to generate
proteins, providing an effective way of generating therapeutic
enzymes and other medically important proteins to produce novel
drugs.
Roche Diagnostics has announced it has settled all litigation in
the United States, Europe and Australia, with Promega concerning
Polymerase Chain Reaction Technology (PCR), ending a decade of
litigation between the two companies.
US researchers think they may have solved the puzzle as to why p53
activity occurs in both the nucleus and cytoplasm during apoptosis.
The discovery could form a basis in the development of new
anti-cancer therapies that target protein...
New techniques aimed at directly controlling the expression of
genes by activating or inactivating them at the DNA level could
lead to drugs for the treatment or cure of almost any disease, say
researchers
Sigma-Aldrich launches its DNA polymerase product for PCR
amplification, which aims to minimise DNA contamination, making it
ideal for researchers looking for a more accurate method in
mutation scanning techniques, and wanting to...
Targeted Genetics has announced the issuance of an
Additional-Associated Virus (AAV) vector technology patent, which
describes a technology that may help to maximise gene expression
efficiency with little or no loss in viral payload.
Scientists in the US have been using DNA buckyballs as a nanoscale
building material, constructing geometric shapes and even working
mechanical devices with the hope of developing this technology for
drug delivery, using synthetic...
A new miniature biosensing laboratory device, which applies the
benefits of micro- and nanotechnology, has been developed, which
processes a patient's DNA indicating whether they are at risk of
diseases, such as cancer.
Researchers have achieved the first ever gene therapy success for
muscular dystrophy using a new systemic approach, which
demonstrated that the scientific challenges that have cast doubt on
gene therapy ever being feasible for children...
Kreatech Biotechnology launches a series of nucleic acid labelling
kits for in situ hybridisation and filter hybridisation
applications. These kits offer the researcher the possibility to
non enzymatically label their target nucleic...
A grant totalling more than $32 million to advance the development
of innovative sequencing lab technologies to reduce the cost of DNA
sequencing and expand the use of genomics in biomedical research
has been awarded by The National...
BioGenex announces the launch of the Xmatrx, a walk-away system for
automation of FISH, ISH, and IHC for molecular diagnostics and
therapeutic target identification and validation as well as cell
and tissue staining applications,...
German biotechnology company ICON Genetics is to start field trials
of a transgenic tobacco crop that will be used to produce an enzyme
with potential as an active pharmaceutical ingredient and as a
catalyst for the manufacture of...
New analysis into the gene therapy market reveals that
toxicological complications and poor therapy efficacy have hampered
the growth of this sector in which new ways must be found to
improve clinical efficiency and generate revenue.
US firms Large Scale Biology Corp and privately-held Planet
Biotechnology have expanded their biomanufacturing program to
extract and purify the latter's lead product, CaroRx, a plant-made
antibody to control dental caries.
A disposable flask bioreactor designed by Swiss company Integra
Biosciences has been shown to boost cell densities in mammalian
cell culture by a factor of 10 in a study.
US scientists have shown that microRNA (miRNA) plays an essential
role in the development of the fruit fly. The discovery means that
miRNA could emerge as a new target for interventions aimed at
treating disease, or as a therapeutic...
Topigen Pharmaceuticals has launched a new 3rd generation chemistry
technology, which has been designed for improving
oligonucleotide-based therapeutics that has the potential for broad
gene-targeting drug applications.
