Millipore unveils rapid microbe detector

Related tags Bacteria Microbiology

Separation and filtration specialist Millipore has launched an
automated system for the rapid detection, response and resolution
of microbial contamination in manufacturing processes.

The Milliflex Rapid Microbiology Detection System and AutoSpray Station is suitable for a range of pharmaceutical and beverage applications, according to the company, which claims that the detection system improves process control, product yield and the timely release of products.

The system is based on adenosine triphosphate (ATP) bioluminescence and can delivers test results in approximately one quarter the time of traditional microbial contamination detection methods, such as membrane filtration (MF) and pour plates.

It can detect and count viable microorganisms down to one colony forming unit (CFU), and delivers reproducible results that correlate with traditional methods in studies, according to the company. The detection system uses pre-sterilized, disposable Milliflex filter units for sample preparation.

For improved detection of living microorganisms, the Milliflex AutoSpray station delivers a uniform application of bioluminescent reagents in 90 seconds. A self-priming micropump ensures that a precise volume of pre-programmed reagent is dispensed. The self-cleaning unit completes its cleaning protocol in five minutes, said Millipore​.

ATP bioluminescence is a rapid method detection technology recognised by the US Food and Drug Administration (FDA)'s process analytical technology (PAT​) initiative, and membrane filtration, which is a recommended methodology in the capture of microorganisms by pharmacopoeias in the US, Europe and Japan.

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