Perbio Science launches drug discovery products at Analytica.
this year's Analytica show in Munich with details of new product
launches for drug discovery.
The European business unit of Fisher Biosciences, which bought Perbio in June 2003, for $714m (€564m) has gone under something of an expansion in recent years, particularly in Europe, where more than 40 jobs were created when an extension to the HyClone bioscience factory in Northumberland opened in 2004.
The new facility was Perbio Science's first European manufacturing site for its HyClone products.
Perbio launched its cellWoRx High Content Cell Analysis system at Analytica with drug researchers and the identification of new targets in mind.
The product is a 4-colour automated imaging system, which simplifies the imaging and analysis of microtitre plates.
It is capable of analysing a full 384-well plate at 0.9 microns per pixel resolution in less than twenty minutes.
For even higher throughput and volume, users have the option of various camera binning modes. The entire imaging path provides uniform sample illumination and repeatable, high-resolution images necessary for high content cellular analysis.
An optimised combination of fixed optics and oblique illumination creates images with superior signal-to-noise ratio and image contrast.
The system is also compatible with SBS standard 6-, 24-, 96- and 384-well plate formats and standard 1" and 3" microscope slides.
"cellWoRx delivers a system for an automated imaging environment," said Sabine de Beuf of Perbio Science.
"At Analytica 2006, we invited researchers from the academic world to the Perbio Science stand where they could see the cellWoRx system demonstrated for the first time in Europe," she added.
The cellWoRx system is manufactured by Applied Precision for Cellomics and is integrated with Cellomics' vHCS Analysis Toolbox software enables researchers to create assays for new biological applications, with protocols that can be easily adjusted to optimise results.
Automated measurement, reporting and data storage functions save development time and improve productivity, while automated analysis makes image-based assays scaleable and robust.
Perbio also make available it's RED Rapid Equilibrium Dialysis Device from Pierce that was launched from the Perbio Science stand.
This new dialysis method in plasma protein binding determination is automation-friendly for the analysis of multiple drug candidates.
The RED Rapid Equilibrium Dialysis Device is designed to provide a high membrane surface-to-volume ratio, reducing dialysis time by 75 per cent when compared to competing devices.
With short incubation times, the dialysis device inserts are pre-assembled, disposable and leak-proof. The 96-well plate format is compatible with automated handlers and the individual insert format also allows for partial plate use.
A reusable Teflon base plate eliminates non-specific binding and crosstalk concerns.
Further details of both products are available at Perbio's website.
