The products, which consist of cryogenic vials and storage systems, storage and packaging vials, microwell plates and sealing tapes, centrifuge tubes, amplification products and reagent reservoirs in manufacturing lots that are designed to be free of RNase and DNase. RNase and DNase are enzymes that catalyse the hydrolysis of nucleic acids. Although RNase is more prevalent than DNase, both can affect the productivity of scientists working with RNA or DNA. RNase and DNase may compromise a variety of experiments, including amplification, northern blot, gene expression and microarray analyses. Subjectivity of genetic experiments to RNase and DNA contamination leads to concern for the possibility of false positive and negative signals.