Asahi launches high-compactable MCC excipient
Asahi Kasei has added to its range of excipients through the launch of Ceolus UF-711, which it claims is the first high-compactable microcrystalline cellulose (MCC) that makes tablets smaller.
The excipients effectiveness in making tablets smaller is especially pronounced in formulations of high-dose drugs with low compactability, according to Asahi, because it is composed of mainly round, porous particles.
In addition Asahi claims these physical characteristics improve the excipients flow and make it effective in challenging tablet formulations.
An example given by Asahi is 75 per cent ascorbic acid in direct compression with a practical level of hardness (more than 50N) and weight relative standard deviation (less than 1.0 per cent).
