Evotec and 4-Antibody team up to "revolutionise" early antibody detection

- Last updated on GMT

Related tags: Antibody

Evotec and 4-Antibody team up to "revolutionise" early antibody detection
Evotec and 4-Antibody have teamed up to offer a new antibody testing service.

Under the deal, Evotec paid out € 2m to access 4-Antibody’s in vitro​ selection tech, the Retrocyte Display, which can express full-length immunoglobulin antibody libraries in mammalian B-lineage cells for the identification of antigen-specific fully human monoclonal antibodies.

The firms plan to couple the platform, which screens large quantities of antibodies, with Evotec’s screening system – also high-throughput.

A spokesperson for the two companies said the cell-lines means desired functionality at a much earlier stage of selection. 

“B-lineage cells are designed by nature for optimal antibody display, and are capable of generating ‘better-behaved’, fully human antibodies,”​ said the spokesperson.

The platform is also said to provide earlier distinction and selection between antagonist and agonist antibodies.  

Pioneers

Robert Burns, 4-Antibody’s CEO said the approach is a leap forward in the field of early detection, and will drastically reduce attrition rates at later development stages.

“Everyone in the drug discovery space understands the desirability of introducing functional testing as early as possible in the selection of drug candidates but I don’t see other service providers who can offer this fully integrated high throughput capability in the antibody drug space,”​ he said.

“We can now offer a fully integrated discovery to development model in the antibody drug space for pharma players who are looking for complete out-sourcing.”

Werner Lanthaler, Evotec CEO, added: “This ‘EVOmAb’ turn-key solution will deliver to our customers a much higher chance to bring an antibody to the market than traditional affinity-selected antibody approaches”

Related news

Show more

Related products

show more

Laboratory Solutions for COVID-19 Clinical Trials

Laboratory Solutions for COVID-19 Clinical Trials

Q2 Solutions | 10-Jun-2020 | Clinical Study

As a leading laboratory services organization for trials across the globe, we are proud to partner with clients to support COVID-19 clinical trials. Our...

Q2 Solutions: Corporate Brochure

Q2 Solutions: Corporate Brochure

Q2 Solutions | 17-Apr-2020 | Product Brochure

We are an innovative, progressive and responsive partner with the global experience, medical expertise and focus on quality that is integral to drug, medical...

Related suppliers

Follow us

Products

View more

Webinars