Recipharm invests in prostate cancer drug and delivery tech firm LIDDS

By Gareth Macdonald contact

- Last updated on GMT

Flickr/ Richard Leonard
Flickr/ Richard Leonard

Related tags: Pharmacology, Cancer, Prostate cancer

Recipharm has invested in delivery tech firm and prostate cancer drug developer LIDDS as part of manufacturing contract.

Recipharm will make LIDDS’ drug candidate Liproca Depot - a modified-release formulation of 2-hydroxyflutamide – for clinical trials according to EVP Development & Technology Carl-Johan Spak, who also told us production will be carried out at its facility in Solna, Sweden.

The compound 2-hydroxyflutamide is the active pharmaceutical ingredient (API) in the generic drug flutamide – which has been used to treat prostate cancer in combination with hormone therapy since the mid 70s.

One difference with LIDD’S formulation is that it is prepared as a paste with the carrier material calcium sulphate.

But the main distinction is that the paste is delivered using a pre-filled syringe - for which LIDDS owns intellectual property rights - that mixes the formulation prior to injection.

Advantages and investment

LIDDS claims the approach is better than current treatments because it causes fewer injection site effects and – as the paste can be visualised using ultrasound - can be delivered more accurately.

As part of the deal – which has been under negotiation since April​ – Recipharm has invested SEK5m ($500,000) in LIDDS, making it the firm#s third biggest backer.

Spak told us Recipharm's investment was motivated in part by the delivery technology, explaining that: “We are confident that the technology can be used for other indications​.”

He added that:  “We certainly hope that LIDDS will continue to find us to be a perfect partner so that we can assist new customers with development of products based on LIDDS proprietary technology.”

Liproca Depot is currently being examined in a Phase II trial​ in Sweden and Finland according to a record on Clinicaltrials.gov. 

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