BioPharma Ambition

ASCO urges industry to share real-world data for clinical trial efficiency

By Flora Southey

- Last updated on GMT

(Image: Getty/Bogdanhoda)
(Image: Getty/Bogdanhoda)
Sharing real-world data between CROs, sponsors and academic institutions will help improve trial design, says cancer association.

“Conventional clinical trials are becoming obsolete,” ​American Society of Clinical Oncology (ASCO) executive Richard Schilsky told delegates last month, arguing that an increasing number of cancer drugs and indications​ is forcing the industry to re-think clinical trials.

With more than 800 new cancer drugs in development – many of which target rare genotypes – it is no longer possible to conduct randomized clinical trials in every population, said Schilsky at the BioPharma Ambition Conference in Dublin, Ireland.

“We cannot learn everything that remains to be learned about all the various subtypes of cancer, by doing individual, prospective clinical trials about each subtype.

“We have to rethink the way we do clinical trials, in order to design clinical trials that are appropriate for the patient populations and the biology that we're trying to study,” ​he said. 

As a result, Schilsky urged delegates collect and share information over the entire lifecycle of the drug: “Learning needs to combine trial data and real-world data.”

The executive argued that firms do not need to know everything they eventually would like to know about a drug, at the time of market entry. While there is certain information required in order to justify market entry, there is a lot of information that can be developed about the drug in the post-market phase, he said.

Related news

Show more

Related products

RACE Act Prompts Pediatric Oncology Trials

RACE Act Prompts Pediatric Oncology Trials

PRA Health Sciences | 04-May-2020 | Technical / White Paper

Many providers prescribe drugs off-label to pediatric patients, even though there have been few pediatric trials for many of these drugs. In response,...

Global Clinical Trial Lab Services

Global Clinical Trial Lab Services

Q2 Solutions | 01-Apr-2020 | Product Presentation

As a leading global lab services partner, we provide operational excellence, scientific leadership and innovation through technology. We offer end-to-end...

Manufacturing Cyto and Non-Cyto Drugs in One Facility

Manufacturing Cyto and Non-Cyto Drugs in One Facility

Baxter BioPharma Solutions | 01-Mar-2020 | Technical / White Paper

Recent market reports suggest increasing product niches, which may lead to decreasing numbers of units per product, making dedicated facilities less practical....

What do big pharma companies spend on R&D?

What do big pharma companies spend on R&D?

Zymewire | 15-Aug-2019 | Technical / White Paper

The free Big Pharma R&D Spend report examines the financial performance and research & development investments of the top 25 pharmaceutical companies...

Related suppliers

Follow us

Products

View more

Webinars