UK-funded study to investigate patients’ experience of cell and gene therapies

By Flora Southey

- Last updated on GMT

(Image: Getty/Nortonrsx)
(Image: Getty/Nortonrsx)

Related tags: Cell, cell and gene therapy, study, Disease, Research

Innovate UK is helping to fund the PROmics study, a programme designed to assess the effect of cell therapies on patient symptoms and quality of life.

UK Research & Innovation (UKRI), via Innovate UK, has granted £1.1m ($1.4m) to researchers and industry partners to investigate patients’ experiences of cell and gene therapies in clinical trials.

The PROmics study is a joint venture between the Midlands & Wales Advanced Therapy Treatment Centre (MW-ATTC), the University of Birmingham’s Centre for Patient Reported Outcomes Research (CPROR), and Dignio, a Norwegian remote health-monitoring firm.

Dignio is responsible for developing the technology, and UK-headquartered Datatrial will integrate the electronic patient reported outcomes (ePRO) data with clinical outcome manufacturing data.

According to a Birmingham Health Partners spokesperson, patients will report their symptoms and quality of life via a tablet – both at the point of receiving therapy and on a longer-term basis.

“[The patients] will be involved in the design of the reporting software/app to ensure it is fit-for-purpose, meets their needs, and is easy to use,” ​the spokesperson added.

Participants will be selected from various disease populations to inform the most appropriate treatments, we were told.

“At this stage, there are several trials in the process of being worked up, and each will involve different types of cells,” ​the spokesperson continued. The first trials being set up and run by the Cancer Research Clinical Trials unit and MW-ATTC will be early phase – Phase I or Phase II, she added.

According to CPROR’s Melanie Calvert, the data generated will then be used to “assess the effectiveness of treatments, support patient care and provide a crucial evidence base for regulators and policy makers.”

“Ultimately, the PROmics study will help establish he safe and efficient delivery of Advanced Therapy Medicinal Products (ATMPs) to patients and also maintain the UK’s leading role globally for developing new therapies,” ​she added.

The PROmics study is due to begin this month.

Related news

Related products

RACE Act Prompts Pediatric Oncology Trials

RACE Act Prompts Pediatric Oncology Trials

PRA Health Sciences | 04-May-2020 | Technical / White Paper

Many providers prescribe drugs off-label to pediatric patients, even though there have been few pediatric trials for many of these drugs. In response,...

Global Clinical Trial Lab Services

Global Clinical Trial Lab Services

Q2 Solutions | 01-Apr-2020 | Product Presentation

As a leading global lab services partner, we provide operational excellence, scientific leadership and innovation through technology. We offer end-to-end...

Manufacturing Cyto and Non-Cyto Drugs in One Facility

Manufacturing Cyto and Non-Cyto Drugs in One Facility

Baxter BioPharma Solutions | 01-Mar-2020 | Technical / White Paper

Recent market reports suggest increasing product niches, which may lead to decreasing numbers of units per product, making dedicated facilities less practical....

What do big pharma companies spend on R&D?

What do big pharma companies spend on R&D?

Zymewire | 15-Aug-2019 | Technical / White Paper

The free Big Pharma R&D Spend report examines the financial performance and research & development investments of the top 25 pharmaceutical companies...

Related suppliers

Follow us


View more