TFF Pharmaceuticals partners with Experic to expand manufacturing

By Jenni Spinner contact

- Last updated on GMT

(photoman/iStock via Getty Images Plus)
(photoman/iStock via Getty Images Plus)

Related tags: Packaging, Manufacturing, Gmp, Contract manufacturing

The clinical-stage pharma firm will install a processing line at Experic’s cGMP facility in New Jersey to handle its thin-film freezing technology.

TFF Pharmaceuticals, a clinical-stage pharmaceutical company that specializes in developing and commercializing novel drug products using its thin-film freezing (TFF) technology, has expanded its engagement with contract manufacturing organization (CMO) Experic LLC. Under the agreement, Experic will install a TFF processing line at the company’s cGMP facility located in Cranbury, New Jersey.

According to the companies, installation of the custom-engineered equipment is expected to wrap in the early second quarter of 2021. The processing equipment installation will give TFF its third cGMP manufacturing location and increase its manufacturing capacity.

The TFF platform was created to help improve the solubility and absorption of poorly water-soluble drugs; according to the company, the technology is especially suited to generate dry-powder particles with properties targeted for inhalation delivery, especially to the deep lung, for respiratory therapies. The TFF process results in a “brittle matrix particle,” which reportedly possesses low bulk density, high surface area, and typically an amorphous morphology. allowing the particles to supersaturate when contacting the target site, such as lung tissue.

Glenn Mattes, CEO and president of TFF Pharmaceuticals, said the expansion of manufacturing operations at Experic provides the company with the capability to develop and produce products currently in assessment with various pharma companies.

Experic has been a terrific partner for us because of their domain expertise in dry powder inhalation products​,” Mattes commented. “They also provide us with unique downstream encapsulation technology that rounds out the specialized manufacturing requirements of our dry powder inhalation therapies​.”

Jeffrey P. McMullen, CEO and chair of Experic, said the company is looking forward to working with TFF and supporting product development and manufacturing.

We share their excitement in the continued advancement and expansion of their technology and business​,” he commented.

Experic offers CMO and pharma supply services across a variety of dosing and packaging formats, including capsule filling, powder and pellet dosing (such as DPI), and autoinjectors and pen assemblies.

Related news

Show more

Related products

show more

Seasonal Vaccine Manufacturing

Seasonal Vaccine Manufacturing

Baxter BioPharma Solutions | 19-Oct-2020 | Technical / White Paper

The production of seasonal vaccines, such as those for influenza, presents unique challenges to manufacturers due to the necessary time constraints resulting...

Innovations in OSD

Innovations in OSD

Recorded the 06-Oct-2020 | Webinar

This DFE series of educational webinars looks at innovations in Oral Solid Dose Forms with the emergence of advanced technologies such as Continuous Manufacturing...

Register for free

Strategies to Achieve Successful Approval & Launch

Strategies to Achieve Successful Approval & Launch

Catalent Pharma Solutions | 03-Sep-2020 | Data Sheet

There are several key considerations to how companies should approach commercial-scale manufacturing that may aid the success of their biologic’s launch...

Related suppliers

Follow us

Products

View more

Webinars