Certara launches version 18 of its physiologically-based pharmacokinetic (PBPK) Simcyp Simulator with new features including advanced food staggering and tumor models to optimize trial design and dose selection.
Real world evidence extraction is one area where Sanofi is using NLP text mining, a technology with applications across the R&D pipeline, from target identification to clinical trial design and pharmacovigilance.
The MI-based CRO MMS Holdings is among the team at the Health Analytics Collective, a research group hoping to reduce the need for new clinical trials by using readily available data – and an MIT-incubated programming language.
The US-based CDMO Cognate intends to collaborate with Astero to provide access to the latter’s cell thawing platform to improve product quality in clinical manufacturing and establish a center of innovation.
Large clinical trials can be particularly useful in the early treatment and prevention of neurodegenerative diseases because of the amount of data collected, though patient recruitment and retention are challenging, says biostatistician.