Balance achieved in biomanufacturing capacity
The notion that there is undercapacity in biomanufacturing has
become common wisdom, but a new study suggest that now supply and
demand are in balance.
Emerson wins Amersham contract
Amersham has signed up Emerson Process Management to automate a new
plant in Norway dedicated to the production of diagnostic imaging
Guidant licenses stent polymer
Medical device multinational Guidant has paid $35 million (€32m) in
cash to acquire the rights to a polymer technology from MediVas for
use in its stent programme.
Amersham helps Isis to oligo milestone
A process developed by Amersham has enabled Isis Pharmaceuticals to
produce the world's largest antisense oligonucleotide synthesis
scale per single run.
Faster organic compound synthesis
Fluorous Technologies has signed a licensing agreement with
Sweden's Personal Chemistry covering syntheses using palladium
catalysts in microwave reactors.
Dow forges cancer collaboration
A collaboration between a Avidex of the UK and Dow Chemical aims to
create a series of new 'biotargeted' radiopharmaceuticals for
Study details best practice in QC
A new report from Best Practices provides a view of how the top
pharma firms manage their quality control to reduce manufacuring
costs and production time.
Human proteins made in yeast
Researchers in the US have managed for the first time to produce a
fully human protein - including complex sugar side chains - in a
Edible vaccines closer to market
Transgenic plant technologies could lead to a revolution in vaccine
production and manufacture; should plant-based vaccines prove
effective in clinical trials, this will drive licensing activity
between key vaccine players and companies...
Long-term plasmid storage feasible
PlasmidFactory has published long-term stability data for its
plasmid DNA, raising the prospects for the technology as a new
source of APIs.
Aastrom gets go ahead for vaccine kits
US biopharmaceutical company Aastrom Biosciences has received
approval to market and sell its DCV-II cancer vaccine production
kits in the European Union. The company believes the market will
offer a new potential path to near-term...
Clariant beefs up clinical manufacturing support
Clariant has announced plans to establish a Technology Centre in
Germany that will support the pharmaceutical industry in the
commercialisation of new drugs.
Sewage is full of drugs, says study
UK study finds sewage treatment is effective in removing
pharmaceutical and personal care product chemicals,although there
some facilities are better than others.
Needle-free injection coming of age
Needle-free injection systems are finally emerging as a serious
alternative to traditional syringes, despite first being introduced
in the middle of the last century.
GSK licenses bioavailability patent
A patent covering a technology aimed at improving the oral
bioavailability of cancer drugs has been licensed by
EuropaBio names keynote speakers
The organisers of CORDIA EuropaBio 2003 have revealed the keynote
speakers for the 'largest convention in Europe for trade,
investment, partnership and information exchange'.
Roche takes crystal-clear route to development
Swiss drugmaker Roche has succeeded in developing a crystalline
form of one of its pipeline compounds with the help of a US
company, TransForm Pharmaceuticals, that is applying a
high-throughput approach to form and formulation.
Transgenic production for the birds
US company AviGenics has successfully produced biologically active
human interferon and human monoclonal antibodies in transgenic
Schott patents coated container for drugs
Germany's Schott Glas has been granted a US patent on a glass
container for storing medicines that incorporates an anti-adherent
coating on its inner surface.
Pfizer pulls out of Phytopharm collaboration
Botanical drug specialist Phytopharm suffered a setback yesterday
when Pfizer withdrew from a collaboration to develop P57, a drug
for obesity and metabolic syndrome.
Nanotechnology advisory group set up in UK
A UK programme aimed at identifying the environmental, health and
safety, ethical and societal implications of nanotechnology has
appointed a working group to oversee the effort.
Degussa buys into "designer" solvents
Degussa has acquired a stake in a company specialising in ionic
liquids, an innovative technology that could provide a greener
alternative to commonly used volatile organic solvents in the
manufacture of pharmaceuticals.
Sweet way to protein production
Scientists have developed a way of making proteins in sugarcane
that they claim will be safe and less expensive than transgenic
approaches using animals.
A new whey for pharma-grade lactose
Australian dairy farmers could become major suppliers of
pharmaceutical-grade lactose, if a new technology developed at the
Commonwealth Scientific and Industrial Research Organisation can be
Emisphere tech aids oral protein delivery
Emisphere Technologies has demonstrated effective oral delivery of
protein-based drugs in three studies presented at the Controlled
Release Society's annual meeting.
Controlled-release - from a softgel
US company Banner Pharmacaps has unveiled what it claims is the
first controlled drug delivery system to be based on a softgel
LipoCore hints at major partner
LipoCore's Galacticle delivery technology is to be the subject of a
feasibility study at one of the largest multinational drug
manufacturers in the autumn
Assay identifies cells for Ab production
One Cell Systems has been awarded a US grant to develop a new
approach for identifying hybridoma cells that produce
Lonza expands into discovery with Vaccinex deal
A deal with Vaccinex has taken Lonza Biologics beyond its primary
focus of mammalian cell culture-based manufacturing and into the
area of antibody drug discovery.
Massachusetts to get biotech boost
Four Massachusetts-based companies have hatched a scheme to develop
a large-scale biotechnology manufacturing facility in the state.
Novo signs up Morphotek for protein enhancement
Novo Nordisk has enlisted the aid of the USA's Morphotek to improve
the manufacturing process for one of its marketed protein
Millipore sees throw-away future
The shift towards full automation with ready-to-use separation
devices is the first step on the path to a completely disposable
manufacturing process, says Millipore
Ultrasound improves biopharma purification
Ultrasound monitoring of process column chromatography can lead to
significant improvements in productivity, lower costs and greater
drug purity, says study
Patch system from LTS gets US patent
Lohmann Therapie-System has been granted a US patent on a new
process for making multilayer laminates that can be used for the
delivery of active pharmaceutical ingredients or cosmetics.
New adjuvant patented by Vical
A new vaccine adjuvant developed by Vical promises to improve the
immunogenicity of gene-based immunization. The company has just
been granted a US patent on the adjuvant.
GSK opens uHTS R&D facility in Spain
GlaxoSmithKline has opened an ultra-high-throughput screening
facility at its site in Tres Cantos, Spain, marking a significant
milestone in the company's bid to develop a more industrialised
approach to the process of drug discovery.
Biolex uses plant to make Centocor proteins
Centocor forged a deal with Biolex in which the latter firm will
examine the feasibility of producing three therapeutic proteins
using a proprietary plant-based expression system
MediGene's R&D quits USA for Germany
MediGene is relocating the entire research department of its US
subsidiary to Germany, delighting those who lament the "brain
drain" of scientific talent flowing in the other direction
New license shores up BioProtein's transgenics IP
BioProtein Technologies has licensed rights to technologies
developed by GTC that will improve its intellectual property
position in transgenic protein manufacture
New formulations set to transform diabetes treatment
There has been a steady increase in the number of diabetes-related
R&D projects in recent years, and one area of particular
interest is the pulmonary delivery of insulin, says a new report
Novartis patents antioxidant container for drugs
Switzerland's Novartis has been awarded a US patent for a novel
means of extending the shelf life of pharmaceuticals. The invention
describes the use of a plastic bottle made from a polymeric
material that is impregnated with...
Surface science improves metal oxide catalysis
Researchers in the USA have generated designer metal oxides with
specific surface properties that can be used as catalysts in the
manufacture of pharmaceuticals and chemicals
Avantium speeds up process R&D for Eastman
Avantium Technologies of the Netherlands, a specialist in
developing high throughput process R&D techniques for customers
in the chemical and pharmaceutical industries, has been signed up
by Eastman Chemical for the discovery...
Towards high-throughput proteomics
Bruker Daltonics has forged an alliance with the US Pacific
Northwest National Laboratory to develop and commercialise mass
spectrometry for high-throughput proteomics research
Improving DNA vaccine delivery
Nature Technology has launched an improved delivery technology for
DNA vaccines that is now available for license by companies working
in this fast-growing area
Oligo licence for Transgenomic
Transgenomic has taken out a non-exclusive licence from Geron in
which it gains manufacturing rights to phosphoramidate and
US patent for pressure-sensitive reaction system
Boston Biomedica has been issued an additional US patent covering
the design and use of its Pressure Cycling Technology for the
control of pressure-sensitive chemical reactions.
New science chief at METabolic EXplorer
METabolic EXplorer, a French biotechnology company specialising in
the development and production of new biological processes for the
manufacturing of chemicals and pharmaceuticals, has bolstered its
scientific team with the appointment...
AstraZeneca takes on TB in India
AstraZeneca has opened a new multi-million dollar research facility
in Bangalore, India, which will focus principally on finding new
treatments for tuberculosis, a disease which is diagnosed in about
8 million people worldwide each...
Merck restructures R&D as diabetes drugs fail
Germany-based drugmaker Merck KGaA has launched a major
restructuring of its R&D activities after shelving two of its
early-stage diabetes product candidates, EML 16336 and IDD 676.