CalbaTech buys RNAi company
CalbaTech has signed an agreement to acquire privately-held
Molecula Research Laboratories, a company developing gene silencing
technologies for gene and protein function studies.
Affymetrix set to ship human genome chip
Affymetrix is taking orders for a new one-chip product that offers
researchers the protein-coding content of the human genome on a
BioFocus extends Roche alliance
BioFocus has entered into an agreement with Switzerland's Roche for
the design of a several custom kinase libraries for use in the
latter's drug discovery efforts.
Elan in pact with BMS
Embattled Elan has signed a deal with BMS that will see its
NanoCrystal drug delivery technology applied to a number of the
latter's drug candidates.
Chemicals follow crops as Bayer reorganises
Germany's Bayer has continued the revamp of its business units by
setting up its chemicals, technology services and healthcare
activities as three separate legal entities. The move follows the
carve-out of Bayer CropScience a...
Qiagen launches bespoke gene expression assays
Qiagen has launched a new version of its Quantitect kit that will
allow users to design and order assays to measure the expression of
any gene from any organism in minutes.
deCODE up on obesity gene find
Iceland's deCODE Genetics saw its US-listed shares rise more than
10 per cent yesterday after it reported the discovery of a gene
that appears to play a role in whether people are lean or fat.
Image analysis from Amersham
Amersham Biosciences has introduced a new software package designed
for the analysis of images from a wide range of biological samples.
EGFtk blocker from Roche disappoints
Another drug targeting epidermal growth factor tyrosine kinase -
Roche's Tarceva, has failed to live up to early promise as a
treatment for lung cancer.
Irish deputy PM to address EuropaBio
Mary Harney, the Irish Deputy Prime Minister and incoming President
of the European Union's Competitiveness Council will speak at the
opening plenary session of the CORDIA - EuropaBio Convention 2003,
on 2 December in Vienna,...
Amersham unveils new stain for proteomics
Amersham Biosciences has launched a new stain, called Deep Purple,
which it claims will improve the detection of proteins in 1D and 2D
Lasers make liposomes tiny test tubes
Using laser light as tweezers and a scalpel, scientists have
demonstrated the use of liposomes as nanovials for ultrasmall
Computers lend a hand in smallpox drug screening
A consortium of companies and academic researchers has completed
the first phase of a mammoth screening programme designed to
discover a small-molecule drug candidate for smallpox.
Tepnel cuts losses as sales climb
Tepnel Life Sciences has trimmed its losses and boosted sales in
the year ended 30 June, helped by the sale last month of its first
robotic Nucleopure DNA purification systems.
German reforms pass first hurdle
The government of Germany has had its controversial health reform
policy voted in by the country's parliament with a comprehensive
Cell-based screening system
CyBio launches a new system designed to help researchers automate
cell-based screening of new drug candidates, ADME/Tox and assay
Perbio agrees to $714m takeover by Fisher
Swedish company Perbio Science has agreed to a $714 million (€626m)
takeover by Fisher Scientific International of the USA, which says
that it sees the acquisition as a means of capitalising on the
strong growth of the life science...
Pharma adopts wait-and-see stance on toxicogenomics
The world market for toxicogenomics technologies is set to grow
strongly over the next five years, but needs the catalyst of
recognition by regulatory authorities.
First gene linked to stroke
Researchers from Icelandic genomics company deCODE Genetics have
discovered the first gene ever linked to ischaemic stroke, raising
the hope that new drugs to treat the condition may be developed.
GSK detector sounds good to Akubio
Akubio bolsters its position in acoustic detection, which uses
sound to detect the interactions between molecules, by licensing a
complementary technology from GlaxoSmithKline.
GSK licenses 'bio-adjuvant'
GlaxoSmithKline has secured rights to a technology, developed in
partnership with US company Advaxis, could improve the
effectiveness of vaccine-based treatments for cancer.
Quicker route to conjugate vaccines
Pall tells BIOPHEX/INTERPHEX conference that use of its
ultrafiltration technologies cuts both the time and cost of
conjugate vaccine production; greater adoption could increase the
availability of vaccines for diseases such as meningitis...
New CEO takes charge at Tecan
Switzerland's Tecan has appointed a new CEO, Aitor Galdos, four
months after the abrupt departure of the former post-holder Emile
FtsZ blocker developed at Merck
Researchers at Merck Research Laboratories have discovered a
small-molecule drug that blocks the activity of FtsZ, an emerging
therapeutic target for antibacterial agents.
BioRobotics bought by US firm
Harvard Bioscience expands in Europe by acquiring UK DNA microarray
and colony picking instrument firm BioRobotics for $3.2 million
SBS: new product round-up
New products unveiled as the SBS annual meeting gets underway
include systems for high-throughput screening, genotyping and patch
Explosion at Sigma-Aldrich plant
A production facility operated by Sigma-Aldrich was rocked by a
serious explosion on Monday. There were no casualties, but the
facility itself has been 'largely destroyed'.
Boom expected in cell culture reagents
The US market for media, sera and reagents used in cell culture is
expected to nearly double in value to reach $1.7 billion (€1.48bn)
in 2008, according to a report.
UK benefiting from German reform?
Healthcare reform and cost containment affecting the rest of Europe
are making the UK increasingly attractive to the branded
CRO industry coming under pressure
Contract research organisation (CRO) revenues have been growing
strongly as a result of drug developers' need to reduce R&D
costs while shortening product evaluation times. However, as demand
for more efficient preclinical...
Drug treatment for CJD?
Quinacrine could provide the first drug treatment for
prion-associated disorders such as Creutzfeldt-Jakob disease,
according to new research presented at ICAAC.
Gene alliance targets diabetes
Roche forges an alliance with ParAllele to discover genes that
contribute to type 2 diabetes, aimed at identifying potential new
medicines and diagnostics for the disease.
SBS: product preview
Next week's Society for Biomolecular Screening annual meeting will
once again be a showcase for dozens of new products in the drug
discovery arena. We preview some of the highlights.
Breathe in the genes
New research has suggested that it may be possible to deliver
therapeutic DNA to the lung using a simple pressurised metered dose
Genevac of the UK has introduced a high performance Model HT-4X
centrifugal evaporator for scientists in the drug discovery and
medicinal chemistry sectors.
Sweden's Nanoxis has secured a financing deal that will help it
develop nanoanalytical platforms - so-called proteinchips - for the
identification of proteins in drug discovery.
AnaSpec buys fluorescence firm
Peptide and antibody specialist AnaSpec has acquired HiLyte
Biosciences, which makes bioanalytical research reagents and kits
designed for scientists engaged in life science research and drug
New antibiotic class cleared for market
The first in a new class of antibiotics has been approved in the
USA for the treatment of complicated skin and soft structure
infections, including those caused by methicillin-resistant
Staphylococcus aureus (MRSA).
Mapping pathways in immunology
A team of researchers at Switzerland's Novartis and Rigel
Pharmaceuticals in the USA have created a method for discovering
molecules that are involved in signalling pathways, according to a
report in the Journal of Biology.
New tools of the trade
New products this week include: a kit for isolating RNA from blood;
a DNA microarray for cytogenetics and cancer research; an automated
mammalian cell picker; and a reagent dispenser for a microplate
Dolly firm faces the chop
The axe looks set to fall on Scottish biotechnology company PPL
Therapeutics now that the company put itself up for sale, having
failed to convince investors of a rescue plan.
Vitamin to help medicine go down
A partnership between Celltech and Access Pharmaceuticals is
focusing on the use of a vitamin-based delivery technology for
monoclonal antibodies and antibody fragments.
BMS has insulin in its sights
Bristol-Myers Squibb has taken another step towards building a
franchise in insulin therapy by licensing an inhaled version of the
drug from QDose for $30m.
Funds galore for EU biotech
Financings for Denmark's ZGene, Xention and DRI of the UK and
Sweden's NeuroNova provide further evidence of a recovery in
Argonaut Technologies has released its latest Synthesis and
Purification catalogue, a technical resource for pharmaceutical
chemists and others involved in all phases of drug discovery and
Cytochrome P450 bioarray
Amersham Biosciences has extended its CodeLink microarray range
with the launch of its Human P450 SNP Bioarray for genotyping and
Big pharma makes foray into gene silencing
Merck & Co has become the first drug major to make a
significant alliance in the field of RNA interference - one of the
hottest topics in drug discovery - via a deal with Alnylam
Kinases and HIV
BioFocus and Axxima report progress in their collaboration looking
at kinase inhibitors as treatments for HIV; assays and lead
Bioinformatics forum for SMEs
On 13 October 2003 the European Bioinformatics Institute (EBI) will
launch a new bioinformatics support network that is tailor-made for
ADMET service from NiKem
NiKem Research says it has developed its ADMET capabilities to such
an extent that it can offer them as a service to customers involved
in drug discovery.