Vitamin to help medicine go down
A partnership between Celltech and Access Pharmaceuticals is
focusing on the use of a vitamin-based delivery technology for
monoclonal antibodies and antibody fragments.
BMS has insulin in its sights
Bristol-Myers Squibb has taken another step towards building a
franchise in insulin therapy by licensing an inhaled version of the
drug from QDose for $30m.
Funds galore for EU biotech
Financings for Denmark's ZGene, Xention and DRI of the UK and
Sweden's NeuroNova provide further evidence of a recovery in
Argonaut Technologies has released its latest Synthesis and
Purification catalogue, a technical resource for pharmaceutical
chemists and others involved in all phases of drug discovery and
Cytochrome P450 bioarray
Amersham Biosciences has extended its CodeLink microarray range
with the launch of its Human P450 SNP Bioarray for genotyping and
Big pharma makes foray into gene silencing
Merck & Co has become the first drug major to make a
significant alliance in the field of RNA interference - one of the
hottest topics in drug discovery - via a deal with Alnylam
Kinases and HIV
BioFocus and Axxima report progress in their collaboration looking
at kinase inhibitors as treatments for HIV; assays and lead
Bioinformatics forum for SMEs
On 13 October 2003 the European Bioinformatics Institute (EBI) will
launch a new bioinformatics support network that is tailor-made for
ADMET service from NiKem
NiKem Research says it has developed its ADMET capabilities to such
an extent that it can offer them as a service to customers involved
in drug discovery.
Flexible head system from Tecan
Tecan has launched a new 384-channel pipetting head that is
suitable for high precision dispensing of volumes - from 200nl to
50µl - in a broad range of fluid-handling applications.
Mega licensing deals for biotech firms
Two $500m-plus licensing deals reveal the rewards available to
biotech firms with novel drugs, but also the lengths large
biopharma companies will now go to secure exclusive rights to
promising candidates, even if they are in the...
Zinsser upgrades Moss system for HTS
Zinsser has launched a sample preparation system - the Moss 2002 -
that makes it easier to process the hundreds and thousands of
compounds used in HTS laboratories
Better than Viagra
A small Korean biotechnology company maps the binding site of
phosphodiesterase-5, the target of Pfizer's Viagra and other drugs
for erectile dysfunction.
Big hitters bash biogenerics
An October conference on biogenerics will see research-based
biopharmaceutical companies and their generic rivals battle to win
the hearts and minds of regulators.
New TOF spectrometer from Waters
Waters has launched a new MALDI-TOF (time of flight) mass
spectrometer, along with a line of porous silicon-coated target
plates and new reference standards,
Thermo chief sees signs of pharma, but not biotech recovery
Companies that supply instruments and consumables to the life
sciences industry have been hit hard by reined in research spending
resulting from the current adverse economic climate. However, one
chief executive believes there are...
Mouse model for kidney stones
A mouse model for cystinuria type I, commonly known as kidney
stones, has been developed by German company Ingenium
Cell signal is brain cancer drug target
US company ComChem has published the first in vivo data in
support of a novel approach to treat malignant glioma, a form of
Mouse genome array from Amersham
Amersham Biosciences has added a mouse genome product in its
CodeLink range, used for drug target identification, pathway
characterisation and drug effect predictions.
Dow forges cancer collaboration
A collaboration between a Avidex of the UK and Dow Chemical aims to
create a series of new 'biotargeted' radiopharmaceuticals for
Hike in Gradipore sales "not enough"
Gradipore has reported a 65 per cent increase in sales for the year
ended 30 June, but said that it was disappointed by the figures,
which did not meet its expectations.
The meanings of genomics
A seminar on 'the meanings of genomics' - to be held in the UK in
November - will examine how genomic data is produced, perceived and
modified in science and society.
Bruker extends TOF/TOF spectrometer range
Bruker Daltonics has launched a compact, high-performance MALDI
-TOF/TOF mass spectrometer that has an affordable price tag,
requires less laboratory space than rival systems and is geared up
for use in proteomics applications.
Hypertension project at Sidec
Sidec Technologies has entered into a contract research
collaboration with a US research institute to study a receptor
involved in the regulation of blood pressure.
Distribution deal for Gentra's Autopure LS
MiraiBio is to act as a distributor of Gentra Systems' Autopure LS
automated large sample nucleic acid purification system and related
consumables in the USA and certain other regions of the Americas.
Inflammation and atrial fibrillation
Italian researchers suggest that patients with atrial fibrillation
may have a genetic predisposition linked to expression of
Orexo expands with CePeP buy
Orexo has acquired fellow Swedish company CePeP in a deal which
brings a broad drug enhancement and discovery platform based on
cell penetrating peptides.
Animal groups bomb Chiron HQ
Chiron's headquarters is hit by two homemade bombs, with an animal
rights group claiming responsibility. The blasts caused no
casualties and only minor damage to property, but represent an
alarming escalation in the tactics used...
Aventis licenses novel dementia drug
Aventis has licensed a drug for Alzheimer's disease and other forms
of dementia from Japan's Dainippon; AC-3933 is claimed to have a
completely novel mechanism of action.
Antisense drug for MS starts trials
An oligonucleotide-based drug that may represent a new treatment
option for multiple sclerosis has started Phase I trials in the UK.
Novartis cancer chief to tackle TB
Alex Matter is to direct the Novartis Institute for Tropical
Diseases (NITD) in Singapore after his retirement as Novartis
oncology chief later ths month.
Central Europe a hotspot for drug trials
Leading CRO says it has seen a marked increase in the number of
trials it has been asked to work on in Central Europe, and believes
the trend is set to continue.
IBM unveils R&D productivity package
IBM has introduced its new InsightLink software, an application to
help pharma companies create searchable online databases that will
enable more sharing of research knowledge.
Edible vaccines closer to market
Transgenic plant technologies could lead to a revolution in vaccine
production and manufacture; should plant-based vaccines prove
effective in clinical trials, this will drive licensing activity
between key vaccine players and companies...
German health reforms drive out Pfizer, Merck
US pharmaceuticals major Pfizer is considering moving some of its
activities in Germany to the UK due to government health reforms;
meanwhile, Merck & Co has shelved plans to open a new R&D
facility in the country.
Long-term plasmid storage feasible
PlasmidFactory has published long-term stability data for its
plasmid DNA, raising the prospects for the technology as a new
source of APIs.
Molecular Probes acquisition
Invitrogen completes $325m purchase of Molecular Probes in a deal
which will take the latter's fluorescence labelling technologies
into new markets.
Merlin eyes Nordic region
UK-based life sciences venture firm Merlin Biosciences is expanding
its European practice into Finland by establishing an office in
FP6 information day for biopharmaceutical SMEs
The emerging biopharmaceutical enterprises (EBE) group will hold an
information day on priority one of the Sixth Framework Programme on
Why research? Just in-license
A new report suggests that pharmaceutical companies reap much
greater rewards from licensing in products than they do in
conducting their own in-house research.
Acumen Explorer price cut
TTP LabTech announced revamp of Explorer microplate range, as well
as price cuts, following its screening marriage with Acumen
Major MS component deal for Oxford Instruments
Oxford Instruments wins €3 million order for superconducting
magnets for use in Thermo Electron's Finnigan LTQ-FT mass
Astex in CYP450 alliance with Fujisawa
UK-based Astex Technology has revealed that it has signed a
structure-based drug discovery agreement with Japan's Fujisawa.
New clue to Alzheimer's pathology
Researchers have uncovered evidence that the first time that
neurotoxic peptide assemblies known as ADDLs are responsible for
Alzheimer's disease in humans.
Clariant beefs up clinical manufacturing support
Clariant has announced plans to establish a Technology Centre in
Germany that will support the pharmaceutical industry in the
commercialisation of new drugs.
Merck drops Karo Bio compound
The lead compound in Merck and Karo Bio's selective oestrogen
receptor modulator collaboration has been dropped after toxicity
emerged preclinical tests.
Safer smallpox vaccine from Acambis
A new-generation smallpox vaccine developed by Acambis may be less
neurovirulent than a rival registered in the USA, while still
providing equivalent immunogenicity.
BioProgress makes first system sales
BioProgress of the UK, which specialises in delivery mechanisms for
the pharmaceutical oral dosage markets, has sold the first two
machines in its line of systems for tablet coating based on its
proprietary coloured cellulose film.
Fisher extends Perbio offer
Fisher Scientific has extended its SK5.3 billion (€573m) offer for
Perbio Science after failing to win the support of more than 90 per
cent of Perbio's investors.
The end of the blockbuster?
A new report from Datamonitor predicts the end of the
pharmaceutical industry's blockbuster product model, pointing to a
dramatic shortfall in growth rates for billion dollar-plus products
out to 2008.