Case Study

Accelerating Lipid Drug Formulation with the Premier Expert System

Format: PDF file | Document type: Case Study

Capsugel

Formulation scientists are increasingly pivotal to pharmaceutical product development. They are often faced with the daunting challenge of identifying the most suitable drug delivery platform among a myriad of options and developing and validating robust systems that address the challenges posed by increasingly complex drug candidates. Further, these challenges must be overcome in ever-shortening times frames. Among platforms, lipid-based formulations, in either soft gelatin or liquid hard shell capsule formats, have become a well-established approach that has been shown to improve the bioavailability and reduce the food effects and uptake variability of poorly soluble compounds. Capsugel has developed an enhanced lipid-based formulation approach that moves beyond predictive modeling and excipient high-throughput screening. This system utilizes a database of experimentally generated phase diagrams, providing unique formulation development support and resulting in increased speed to market. 

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