Technical / White Paper

Applying disruptive technologies in mammalian cell line development

Format: PDF file | Document type: Technical / White Paper

Fujifilm

Biopharmaceutical manufacturers traditionally rely on cell line development (CLD) “platforms” which combine long development timelines with unpredictable and extensive variation. In this review, we describe the current status of CLD and describe emerging technologies which offer the potential of greater reproducibility and speed. The challenge remains how to reliably incorporate these disruptive technologies and it is thought that systems biology approaches will enable their rational implementation.

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