Development of a coated ODT formulation
Orally Disintegrating Tablets (ODTs) are patient friendly delivery systems being far more convenient than the traditional “tablet and a glass of water”. When some active ingredients cause aesthetic defects on the tablets or a bad taste, the coating remains an interesting option. Since ODTs are intended to disintegrate fast upon contact with a hydrophilic environment, their coating is a challenge. The good stability of Roquette’s ODT platform PEARLITOL® Flash and the performance of the aqueous coating system ReadiLYCOAT® enabled the coating of the ODTs by keeping a similar disintegration time.