Case Study

Development of a coated ODT formulation

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Development of a coated ODT formulation

Orally Disintegrating Tablets (ODTs) are patient friendly delivery systems being far more convenient than the traditional “tablet and a glass of water”. When some active ingredients cause aesthetic defects on the tablets or a bad taste, the coating remains an interesting option. Since ODTs are intended to disintegrate fast upon contact with a hydrophilic environment, their coating is a challenge. The good stability of Roquette’s ODT platform PEARLITOL®​ Flash and the performance of the aqueous coating system ReadiLYCOAT®​ enabled the coating of the ODTs by keeping a similar disintegration time.

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