Dow AFFINISOL™ polymers for Solubility Enhancement

Format: External webinar | Document type: Webinar

Dow Pharma & Food Solutions
Dow has developed the AFFINISOL™ line of excipients to enable solubility enhancement.Hypromellose acetate succinate (HPMCAS) has proven effective at producing stable amorphous solid dispersions for poorly soluble APIs. We will highlight:Utility of commercial grades of AFFINISOL™ HPMCASAFFINISOL™ HPMCAS Quality by Design sample sets in the formulation of solid dispersionsInnovative high productivity HPMCAS polymer providing similar product performance while reducing solution viscosity allowing for increased solids loading in the feed solution.AFFINISOL™ HPMC HME provides a broader extrusion operating window, improved melt flow and resistance to color change at elevated temperatures. The study shows:Processing versatility of this polymer in HMEPolymer utility in solubility enhancement


Kevin O’Donnell Kevin O’Donnell Associate Research Scientist
Dow Pharma & Food Solutions

William “Trey” Porter III William "Trey" Porter III Associate Research Scientist
Dow Pharma & Food Solutions

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