Technical / White Paper

Human study: gelatin & HPMC capsule bioequivalence

Format: PDF file | Document type: Technical / White Paper | Promoted Content

This Technical / White Paper has been written by Capsugel , and any views and opinions expressed do not necessarily reflect those of

Human study: gelatin & HPMC capsule bioequivalence

Rapid and consistent in-vivo drug dissolution is critical for drug absorption. However, in-vitro dissolution results do not always correlate with the in-vivo behavior of drug products. Tablets and capsules can have very different profiles, depending on their composition and processing conditions. In a recent human in-vivo study, an IR tablet formulation containing three drugs with different solubility profiles was encapsulated in either a hard gelatin or HPMC capsule. Download this whitepaper to read how the dissolution rate impacts on the bioequivalence of the formulation.

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