Technical / White Paper

VALSYNTHESE – Custom phosgenation under GMP

Format: PDF file | Document type: Technical / White Paper | Promoted Content

This Technical / White Paper has been written by Valsynthese SA , and any views and opinions expressed do not necessarily reflect those of www.outsourcing-pharma.com

VALSYNTHESE – Custom phosgenation under GMP

Phosgene is a powerful reagent allowing the straightforward synthesis of key intermediates such as chloroformates, acid chlorides, and carbamoyl chlorides. Phosgenation permits the selective and efficient production of isocyanates, N-carboxy anhydrides (NCA’s), carbonates, carbamides, and ureas.

Swiss custom manufacturer VALSYNTHESE has built a state of the art GMP phosgenation plant. Phosgene is generated continuously at 10 – 40 kg/h and supplied to a 4 m3 reactor.

Thus, VALSYNTHESE can support customers with phosgenations from the first development batches to commercial production.

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