APIs (active pharmaceutical ingredients)

78 Results

Generic method approach for determination of residual solvents in active pharmaceutical ingredients by gas chromatography

Content provided by Almac Group | 29-Nov-2023 | White Paper

Solvents are defined as organic chemicals that are used to dissolve components. They are used during the manufacture of drug substances and can also potentially...

Increasing the Bioavailability of Oncology Drugs

Content provided by Lonza Small Molecules | 13-Nov-2023 | White Paper

Oral tyrosine kinase inhibitors (TKIs) are a class of cancer drugs that can be highly susceptible to issues with solubility in the gastrointestinal tract

Efficient Freezing & Storage of Biopharmaceuticals

Content provided by Single Use Support | 06-Nov-2023 | White Paper

Various options exist for freezing biopharmaceutical bulk material, but selecting the most effective and efficient approach for each cold chain can be...

Manufacturing Drugs with Highly Potent APIs

Content provided by Altasciences | 28-Sep-2023 | White Paper

In this issue of The Altascientist, we examine the critical considerations for the safe and compliant manufacture of drugs with highly potent APIs (HPAPIs),...

A Guide Through the API Drug Development Pipeline

Content provided by Lonza Small Molecules | 11-Jul-2023 | Insight Guide

With the complexities associated with API and HPAPI drug development, it’s necessary to lean on the experts. With Q&A sections, insights and articles...

Strategies and tactics for success in biologics analytical testing

Content provided by Bora Pharmaceuticals | 13-Jun-2023 | White Paper

The biopharma landscape is forever changing, and with it, a demand from both patients and investors for the rapid development and progression of drug products...

Life Cycle Extension: A Molecule’s Full Potential

Content provided by Piramal Pharma Solutions | 16-Feb-2023 | White Paper

Winning approval for a new molecular entity is just a staging post on the journey of a drug. To maximize the benefits of a therapy, drugmakers need to...

Using Operational Excellence to Unlock Capacity in API Manufacturing

Content provided by Piramal Pharma Solutions | 15-Nov-2022 | White Paper

Operational Excellence (OE) is a key element of organizational leadership and intelligence. For a CDMO operating in the pharmaceutical industry, OE focuses...

INDENA ALWAYS AT THE FOREFRONT FOR CDMO SERVICES

Content provided by Indena | 25-Oct-2022 | White Paper

Indena is well known in the space of naturally derived molecules, with a know-how developed over its one hundred year history. At the same time, the company...

The Performance of PROSOLV® EASYtab SP in 4 Medium-Dose, Direct Compression Formulations

Content provided by JRS PHARMA | 30-Sep-2022 | White Paper

In the present study, the performance of PROSOLV® EASYtab SP was tested in four DC formulations with different model APIs.

Pediatric Formulations: Identifying & Addressing Children’s Needs

Content provided by Piramal Pharma Solutions | 30-Jun-2022 | White Paper

Developing formulations for pediatric patients poses unique challenges. The specific needs of children, which vary by age, mean the task goes beyond scaling...

Nanomilling for Better Solubility and Bioavailability

Content provided by Altasciences | 07-Apr-2022 | White Paper

40% of marketed drugs and 90% of active pharmaceutical ingredients (APIs) are poorly water-soluble. Nanomilling is a proven technique that can overcome...

Eastern & Western Manufacturing Solutions

Content provided by Piramal Pharma Solutions | 15-Mar-2022 | White Paper

The best manufacturing site for a product can change throughout the life cycle. When bringing new drugs to market, biopharma companies may benefit from...

Flexibility and capability in pre-filled syringes

Content provided by Curia | 15-Nov-2021 | White Paper

Pre-filled syringes have risen in popularity in recent years but the pandemic’s impact on drug development, manufacturing and patient care has created...

INDENA’S CUSTOM DEVELOPMENT AND MANUFACTURING SERVICES FOR APIS AND HPAPIS

Content provided by Indena | 08-Nov-2021 | White Paper

Indena’s Custom Development & Manufacturing Organization services oﬀers a full range of manufacturing capabilities for pharmaceutical ingredients....

LACTIUM®: dairy bioactive to soothe your pet

Content provided by Ingredia | 12-Oct-2021 | Infographic

Lactium® gives you the chance to better meet your pet’s needs for a more harmonious life together. Lactium® acts on the brain and has no side-effects,...

Overcoming Solubility Challenges with Liquid-Filled Capsules

Content provided by Altasciences | 28-Sep-2021 | White Paper

Poorly soluble molecules comprise more than 70% of the small molecule products entering the drug development pipeline today, and are difficult to formulate...

Bioavailability Enhancement Techniques to Improve Patients' Lives

Content provided by Piramal Pharma Solutions | 16-Sep-2021 | White Paper

Oral bioavailability is a constant challenge for developers of new chemical entities. Low solubility and permeability often reduce the fraction of an orally...

Facilities: Lexington, KY USA

Content provided by Piramal Pharma Solutions | 23-Aug-2021 | Insight Guide

The Piramal Pharma Solutions facility in Lexington, KY USA is a fully integrated site which offers analytical, formulation development, and manufacturing...

Facilities: Sellersville, PA USA

Content provided by Piramal Pharma Solutions | 23-Aug-2021 | Insight Guide

The Piramal Pharma Solutions facility in Sellersville, PA USA is a fully integrated site that offers product and process development, clinical supply and...

Lactium® significantly reduces stress-related symptoms

Content provided by Ingredia | 05-Aug-2021 | Product Brochure

Lactium® is a milk protein hydrolysate which contains a bioactive decapeptide with soothing properties called α-casozepine. It decreases anxiety-related...

Facilities: Riverview, MI USA

Content provided by Piramal Pharma Solutions | 26-Jul-2021 | Insight Guide

The Piramal Pharma Solutions facility in Riverview, MI, USA can support your Drug Substance (API) needs. The site has extensive experience in safely delivering...

Facilities: Morpeth, UK

Content provided by Piramal Pharma Solutions | 26-Jul-2021 | Insight Guide

The Piramal Pharma Solutions facility in Morpeth, UK offers Active Pharmaceutical Ingredients (APIs) and oral solid drug product development, clinical...

Integrated Solutions for Accelerated Time to Market

Content provided by Piramal Pharma Solutions | 08-Jun-2021 | White Paper

Facing capacity constraints? Lock in your program now! With 14 sites around the world providing diverse services ranging from discovery to drug substance...

Lactium, your ally to manage day to day stress

Content provided by Ingredia | 27-Aug-2020 | Product Presentation

Stress has been called the ‘health epidemic of the 21st century’ by the World Health Organization. Increasingly, consumers are looking for safe, reliable...

Accelerated development of first-in-human programs. Lonza’s SimpliFiH® Solutions

Content provided by Lonza | 25-Aug-2020 | Sponsored Link

The presented program is laid out as integrated Drug Substance, Particle Engineering and Drug Product services, enabling drug substance and drug product...

INDENA'S INNOVATIVE TECHNOLOGY FOR THE APIS MARKET

Content provided by Indena | 08-May-2019 | Application Note

A pilot pharmaceutical plant for small scale productions and a new spray drying system are the new suites Indena will open at its main production site,...

Strategies to Select and Deliver the Right Candidate

Content provided by Catalent | 05-Mar-2018 | White Paper

Does your candidate have what it takes to succeed? Do you have the information needed to make the right decisions about your candidate’s path to the clinic?...

Why managing variability?

Content provided by SIO/ADM | 02-Oct-2017 | Research Study

Significant efforts are necessary to develop an active pharmaceutical ingredient (API). It is therefore risky to expose this API to poorly characterized...

VALSYNTHESE – Custom phosgenation under GMP

Content provided by Valsynthese SA | 01-Mar-2017 | White Paper

Phosgene is a powerful reagent allowing the straightforward synthesis of key intermediates such as chloroformates, acid chlorides, and carbamoyl chlorides....

Producing the perfect soft gel

Content provided by Leading manufacturer of gelatine and collagen peptides | 17-Jan-2017 | White Paper

This white paper outlines the key considerations to ensure gelatin is enhanced for soft gel formulation, efficient gel production and optimal API delivery...

Patient-Centric Drug-Development Process

Content provided by Catalent | 28-Nov-2016 | Insight Guide

For large and small pharmaceutical companies alike; developing a new drug is fraught with risk. Patient-centric drug development and optimization is both...

pH measurement: Six technical tips

Content provided by Metrohm – customized analysis for the pharmaceutical industry | 10-Oct-2016 | White Paper

The pH value is one of the most important and therefore also one of the most frequently measured quantities in analytical chemistry. Sometimes a simple...

A unique pharmaceutical oil for solubility and oral bioavailability enhancement

Content provided by Gattefossé | 01-Oct-2016 | White Paper

This white paper features Maisine® CC, Gattefossé’s tradename for glyceryl monolinoleate (USP-NF), also known as corn oil mono-, di- and triglycerides....

Elemental Impurity Analysis in Pharmaceuticals – The Road To Implementation of ICH Q3D

Content provided by Butterworth | 13-Sep-2016 | White Paper

The International Conference of Harmonisation (ICH) guidance document on elemental impurities, Q3D, reached step 4 in December 2014, meaning the final...

Influence of AFFINISOL™ viscosity on HME processability and drug release

Content provided by Information not available | 12-Sep-2016 | White Paper

Four grades of AFFINISOL™ HPMC HME were synthesized to specific target viscosities to first assess the ability to control the dissolution rate of a poorly...

FOR SALE/LEASE CRO/MRO turn key Research Campus, labs, vivariums, OR, archives, offices

Content provided by Northstar Private Capital LLC | 09-Aug-2016 | Product Brochure

Chazy, New York is located only six miles from the Canadian Border in Upstate New York. It is only ten minutes North of Plattsburgh, one hour south of...

How to Successfully Combine Multiple APIs Into a Single Dose

JRS PHARMA | Recorded the 07-Jun-2016 | Webinar

Over the years, multiple active pharmaceutical ingredients (API) have been successfully combined into single dosage forms primarily through tablets and...

Considerations in Purchasing a LIMS

Content provided by Abbott Informatics | 27-Apr-2016 | White Paper

Many scientific enterprises find themselves in need of a Laboratory Information Management System (LIMS) to replace an incumbent system, whether an existing...

Advanced Analytics architecture and the benefits it serves as an integrated solution

Content provided by Abbott Informatics | 18-Apr-2016 | White Paper

A laboratory’s day-to-day operations are recorded through STARLIMS, accumulating data over time.This data includes sample lifecycle information and metadata.A...

High energetic and Phosgene reactions in safe hands

Content provided by Valsynthese SA | 01-Mar-2016 | White Paper

Valsynthese, expert in high energetic and hazardous fine chemical production of key intermediates and APIs, is devoted to delivering high quality services...

Next Generation HPMC Capsules: Bioequivalence and Functional Performance

Capsugel | Recorded the 17-Feb-2016 | Webinar

Two-piece hard shell capsules made from hydroxypropyl methylcellulose (HPMC) are emerging as an alternative to conventional gelatin capsules for oral drug...

Excellence in Pharmaceutical Analysis

Content provided by Butterworth | 01-Jan-2016 | Data Sheet

Butterworth specialise in Quality Control Analysis, Method Development, Validation & Stability Testing of Raw Materials, API, Finished Product and...

Enhanced Sampling and Calibration Procedures for the Analysis of Residual Oxygen in Nitrogen Purged Pharmaceutical Packaging by GC-TCD

Content provided by Butterworth | 23-Sep-2015 | White Paper

The classic Modified Atmosphere Packaging (MAP) application, in the pharmaceutical industry, uses medical grade nitrogen to purge atmospheric oxygen and...

Enhanced Residual Solvents Analysis: A Practical Approach to Sampling, Delivery, Storage and Analysis.

Content provided by Butterworth | 12-May-2015 | White Paper

Samplestorage, handling anddelivery are as important in the determination of residual solvents as the analysis itself. This paper provides practical advice...

Amino Acid Analysis According to Ph.Eur 2.2.56

Content provided by SGS Life Science Services | 23-Feb-2015 | White Paper

Employing spectrophotometry and liquid chromatography quantitation of Ninhydrin-positive substances achieves 0.05% reporting sensitivity as required by...

A Method to Meet the New Ph Eur Ninhydrin-Positive Substances Requirement

Content provided by Butterworth | 03-Feb-2015 | White Paper

The European Pharmacopeia (Ph Eur) is moving away from the historical thin layer chromatography technique for the determination of Ninhydrin-positive substances,...

USP<233> Elemental Impurities Sample Prep Strategy

Content provided by SGS Life Science Services | 03-Nov-2014 | White Paper

Although USP <232> and <233> are still under discussion, a good deal of work is going on ahead of implementation in terms of method development....

Comparison Trials on Herbal Extract Syrups Based on LYCASIN® 80/55 and Simple Sucrose

Content provided by Roquette Pharma Solutions | 01-Sep-2014 | Case Study

Formulating a sugar-free syrup being at the same time stable and with a pleasant taste can be a real challenge. LYCASIN®, a liquid maltitol with a sweet...

Technology Selection To Enhance Oral Bioavailability

Content provided by Capsugel | 20-Aug-2014 | White Paper

Effective technology selection for improving bioavailability (BA) can accelerate the development of promising compounds and reduce the overall cost and...

Suppliers

Altasciences

William Reed

Product Innovations