APIs (active pharmaceutical ingredients)

Expansion of precision oncology pipeline announced by Exscientia

23-Mar-2023 By Liza Laws

Challenging target profiles can be targeted more efficiently than traditional drug discovery using Exscientia’s AI-driven precision design platform, its CEO says.

Vaxart reduces workforce and pauses COVID-19 vaccine development

20-Mar-2023 By Ben Hargreaves

The developer of oral vaccines announces a restructure of its business priorities, as it looks to conserve cash to progress its norovirus candidate.

Bluepharma invests €30M in industrial unit for oncology drugs

20-Mar-2023 By Liza Laws

Portuguese pharma company, Bluepharma, has opened an industrial unit specializing in producing oral solid, high potent drugs in the oncology area.

Acesion's positive trial data for treatment of atrial fibrillation

19-Mar-2023 By Liza Laws

Positive data from a phase 2 clinical trial has proven the general mechanism of action of SK channel inhibition for treatment of atrial fibrillation (AF), an abnormal heart rhythm.

CatSci Ltd and AGC Pharma Chemicals announce their strategic partnership

16-Mar-2023 By Liza Laws

Medicine developer, CatSci Ltd announced yesterday (March 15) that it has formed a new partnership with AGC Pharma Chemicals, a small molecule Contract Development and Manufacturing Organisation (CDMO).

LEO Pharma and ICON plc collaborate to improve outcomes for dermatology patients

14-Mar-2023 By Liza Laws

A strategic partnership between LEO Pharma and ICON plc, a clinical development company, was announced on March 10.

Grifols and Selagine collaborate to produce 'game-changing' dry eye disease treatment

14-Mar-2023 By Liza Laws

Grifols has entered into a collaboration and licensing agreement with Selagine to develop immunoglobulin (Ig) eye drops to treat dry eye disease.

LG Chem targets becoming top 20 oncology company

14-Mar-2023 By Ben Hargreaves

After completing the acquisition of Aveo, the Korean chemical company wants its subsidiary to become a global leader in the therapeutic area within five years.

Patent for Poolbeg's immunomodulator aimed at treating hypercytokinaemia

13-Mar-2023 By Liza Laws

Poolbeg Pharma plc has been granted a patent by the US Patent and Trademark Office (USPTO) for ways of treating hypercytokinaemia using a small molecule immunomodulator.

Janssen dual action tablet for prostate cancer gets recommended marketing authorization

13-Mar-2023 By Liza Laws

Small molecule drug, Niraparib combined with abiraterone acetate (AA) and prednisone (P) significantly reduces the risk of disease progression, or death, in patients with a type of prostate cancer, a consultant in Spain has said.

Decentralized Trials

Greater digital biomarklers adoption in clinical studies as Koneksa and SSI Strategy collaborate

08-Mar-2023 By Ben Hargreaves

The two partners will pool capabilities to provide an expanded service to their clients, which will see Koneksa provide its digital biomarkers tools and SSI Strategy its expertise in drug development.

Dr Reddy’s snaps up generic manufacturer’s US portfolio

06-Mar-2023 By Ben Hargreaves

The Indian company seals deal with Mayne Pharma Group to acquire its portfolio of US products in a multimillion dollar deal.

Swiss trading and data analytics platform Kemiex attracts strategic investors

24-Feb-2023 By Jane Byrne

Kemiex has secured equity investments from the strategic investment arm of CME Group, CME Ventures, the global data and analytics company DTN, as well as the family office Wille Finance.

Belharra emerges with $130m and Genentech partnership

09-Jan-2023 By Ben Hargreaves

The newly launched biotech is looking to develop small molecule drugs using its photoaffinity-based chemoproteomics platform.

Phlow and US Pharmacopeia open labs for API R&D services

03-Jan-2023 By Ben Hargreaves

The partners announce that their lab facilities have opened, equipped with advanced manufacturing technologies to create API and KSMs.

Metrion leases facility, adds high-throughput capacity to support ion channel services

08-Dec-2022 By Nick Taylor

Metrion Biosciences has leased a new facility and added high-throughput screening (HTS) capacity to support its ion channel drug discovery projects.

BioNTech links up with Ryvu on small molecule immunotherapy

06-Dec-2022 By Ben Hargreaves

BioNTech and Ryvu Therapeutics will collaborate to develop oncology programs, with the pair announcing that they will work together as part of a multi-target research collaboration.

Novartis plans to take malaria treatment through to P3 trials

28-Nov-2022 By Ben Hargreaves

Both Novartis and Medicines for Malaria Venture will progress an optimized version of lumefantrine into late-stage trials.

EQRx backtracks on plans to reduce pricing of lead cancer treatments

21-Nov-2022 By Ben Hargreaves

For its two lead oncology programs, the company will pursue “market-based pricing”, moving away from plans to “dramatically lower prices” for treatments.

With endpoints already met, GSK halts trial into new antibiotic

14-Nov-2022 By Ben Hargreaves

The first oral antibiotic treatment for urinary tract infections in over 20 years appears to be possible, after interim analysis advised for trials to be stopped after endpoints were met.

Aqemia raises €30m to scale drug discovery platform

31-Oct-2022 By Ben Hargreaves

The company states that its platform combines quantum-inspired physics and machine learning to accelerate drug discovery.

Anji Pharma and Population Health partner to progress lead candidates

31-Oct-2022 By Ben Hargreaves

The biopharma company and investment firm will cooperate to progress late-stage clinical assets in diabetes and chronic idiopathic constipation.

CPHI Pharma Award finalists announced

26-Oct-2022

The awards cover innovations spanning the full pharmaceutical supply chain and feature many of pharma’s biggest names and breakthrough companies.

Alphabet-backed Calico partners to harness computational drug discovery

25-Oct-2022 By Ben Hargreaves

Calico and Terray Therapeutics announced a research collaboration to discover and develop small molecule therapeutics for diseases of aging.

Heron scoops approval for IV postoperative nausea treatment

24-Oct-2022 By Ben Hargreaves

Heron Therapeutics receives approval for its intravenous (IV) injection version of aprepitant, which had previously only been delivered orally.

Ayala Pharmaceuticals reports promising data from Desmoid Tumors trial

19-Oct-2022

Updated interim results from Part A the RINGSIDE pivotal Phase 2/3 study of the company’s AL102 new drug showed consistent early tumor shrinkage with measures deepening over time, plus good tolerability at all doses.

“Significant Step Forward” for Actinogen’s Alzheimer’s treatment

12-Oct-2022 By Maggie Lynch

Clinical data findings from Actinogen’s Phase 2a study measuring the effects of Xanamem in patients with biomarker-positive Alzheimer’s Disease validated company’s ongoing program.

Mallinckrodt applies to FDA for inhaled nitric oxide delivery system

10-Oct-2022 By Ben Hargreaves

The company announces the submission of a 510(k) premarket notification application for its investigational inhaled nitric oxide delivery system for its INOmax gas product.

AION Labs creates AI startup to increase success of drug candidates

06-Oct-2022 By Ben Hargreaves

OMEC.AI is the first startup to emerge from the alliance of pharma companies and investors that created AION Labs, and will focus on improving the efficacy and safety of drug candidates.

Gilead takes legal fight to ‘kingpins’ of counterfeit HIV medicine

04-Oct-2022 By Ben Hargreaves

The company announces further measures against a counterfeiting network it accused of being responsible for selling illegitimate Gilead HIV medications.

TransCelerate CEO: Speeding drug development a ‘win-win’ for all concerned

28-Sep-2022

TransCelerate BioPharma continues to work towards “bringing new medicines to patients faster”. We caught up with the organization’s CEO to hear about its main achievements over the past decade and learn about what comes next.

Pfizer strengthens AI drug discovery collaboration with equity investment

26-Sep-2022 By Ben Hargreaves

Pfizer and CytoReason have been partnered on artificial intelligence and machine learning technologies for drug discovery and development since 2019. The latest deal brings the companies closer.

Intranasal TIPs therapy study shows potential to reduce COVID-19 transmission

19-Sep-2022 By Maggie Lynch

Gladstone Institutes seek FDA approval for human clinical trial after single-dose, intranasal TIPs treatment for SARS-CoV-2 infection limits transmission in infected animals by decreased viral shedding.

Lonza expanding dry powder inhalation capabilities at Florida site

01-Sep-2022 By Jenni Spinner

In response to rising demand for inhalable treatments geard toward respiratory conditions, the company is adding capabilities and capacity at its Tampa site.

Market demands, trends impacting APIs and excipients: MilliporeSigma

31-Aug-2022 By Jenni Spinner

An expert from the company discusses how ever-changing patient needs and other dynamic factors are likely to impact pharma ingredient trends down the road.

Synthetic bio company Antheia raises $40m, announces new pilot plant

31-Aug-2022 By Jenni Spinner

The synthetic biology company which specializes in producing ingredients for plant-inspired medicines has a pilot-scale manufacturing facility in the works.

New WuXi STA plant to tackle growing HPAPI demand

31-Aug-2022 By Jenni Spinner

A company leader advises that the growing need for high-potency active pharmaceutical ingredients calls for CDMOs that consistently deliver quality at scale.

Cutting ‘pain points’ can streamline chemical reporting: ACD/Labs

30-Aug-2022 By Jenni Spinner

A representative from the R&D tech provider offers advice on how to wrangle with a stressful, complicated process for better results and fewer headaches.

Tech Innovations: August 2022

22-Aug-2022 By Jenni Spinner

This month’s news on technology, partnerships, expansions, and more includes items from IQVIA, Almac Group, Signant Health, Lonza, and other key companies.

People on the Move: August 2022

04-Aug-2022 By Jenni Spinner

This month’s announcements of appointments, partnerships, expansions, and mergers include Curia, Thread, TFF Pharmaceuticals, and other notable companies.

Novasep-PharmaZell commits nearly$7.5m to boosting API capacity

01-Aug-2022 By Jenni Spinner

The contract development and manufacturing organization plans to invest €7.3m to expand and upgrade API production capacity at its Mourenx, France facility.

Piramal Pharma Solutions opens doors on API production plant

13-Jul-2022 By Jenni Spinner

The contract development and manufacturing organization's active pharmaceutical ingredient manufacturing operation is located at its site in Aurora, Canada.

Eli Lilly gets speedy NICE recommendation for breast cancer treatment

06-Jul-2022 By Jenni Spinner

England's cost-effectiveness watchdog has recommended Eli Lilly’s Verzenios treatment as an option for adjuvant treatment of certain forms of breast cancer.

bio 2022

Pandemic highlights need for supply chain visibility, partnerships

14-Jun-2022 By Jenni Spinner

During BIO International, US leaders shared lessons learned from COVID-19, and how government and industry are collaborating to avoid future supply chain crises.

CPHI North America

Future drugs will need novel excipients: IPEC

04-May-2022 By Jenni Spinner

An expert from the organization discusses ahead of his CPhI North America presentation how tomorrow’s drugs can’t all be formulated with yesterday’s excipients.

CPhI North America 2022

Pharma growth, partnerships focus of 2022 CPhI North America

04-May-2022 By Jenni Spinner

A leader from the organizer of the pharmaceutical event discusses what’s in store for the upcoming conference, and for the drug development industry itself.

CPHI NORTH AMERICA 2022

US pharma hubs: The rising stars to watch

04-May-2022 By Rachel Arthur

CPhI North America 2022 host city Philadelphia is set to become one of the world’s biggest cell and gene therapy manufacturing hubs. But it’s just one of many centers of innovation that are helping drive the US pharma and biopharma industry.

Proposed bill aims to encourage US pharmaceutical manufacturing

03-May-2022 By Jenni Spinner

Introduced by two Republican Congressmen, the American Made Medicine Act is intended to boost domestic drug manufacturing and create jobs in the sector.

HPAPI Summit hones in on pharmaceutical manufacturing risk

25-Apr-2022 By Jenni Spinner

The 2022 edition of the Highly Potent Active Pharmaceutical Ingredients Summit (June 28 to 30 in Boston) will take on a range of topics, including safety.

Lonza expands API development capacity at Nansha, China plant

21-Apr-2022 By Jenni Spinner

The pharma manufacturing specialist is increasing capacity at its development and manufacturing labs to meet growing global demand for highly potent APIs.