Preclinical

In Vivo Evaluation of a Gastro-Resistant HPMC-Based “Next Generation Enteric” Capsule

Content provided by Lonza Capsules & Health Ingredients | 01-Sep-2023 | White Paper

Invivo: Many orally dosed APIs are bioavailable only when formulated as an enteric dosage form to protect them from the harsh environment of the stomach....

Small Molecule development – getting it right

Content provided by Lonza Small Molecules | 20-Jun-2023 | Insight Guide

Small Molecule drug development is something more and more ambitious emerging pharmaceutical companies are taking on from end to end. But this path can...

CNS Drug Development―One Partner From Discovery to Market

Content provided by Altasciences | 02-May-2023 | White Paper

As a leading partner in central nervous system (CNS) drug development, Altasciences’ in-house preclinical, clinical, bioanalytical, and manufacturing teams...

How Sponsors Reduce Chaos in Decentralized Trials

Content provided by Florence Healthcare | 08-Mar-2023 | Insight Guide

89% of research sponsors currently use and expect to continue the use of decentralized technologies and methods, according to our state of the industry...

The Complexities of Ophthalmic Drug Development

Content provided by Altasciences | 04-Oct-2022 | White Paper

Ophthalmic drug development comes with a unique set of challenges that can be mitigated by working with an end-to-end solution provider with regulatory...

Implementing Patient Co-Creation in Clinical Trials

Content provided by THREAD | 14-Jun-2022 | Insight Guide

Patient co-creation in clinical research means a shift from thinking about the patient to thinking with the patient. This means that patients are giving...

Strategic Approach to Immunogenicity Assessment

Content provided by Altasciences | 17-May-2022 | White Paper

In this issue of The Altascientist we provide a detailed overview on the different goals and challenges that are presented by the validation of immunogenicity...

Clear Guidelines for IND/CTA

Content provided by Altasciences | 24-Feb-2022 | White Paper

There are many challenges associated with early drug discovery and development. Advancing your best candidate for regulatory submissions requires a careful...

Planning Your Preclinical Assessment

Content provided by Altasciences | 17-Jan-2022 | White Paper

There are many challenges associated with early drug discovery and development. Advancing your best candidate for regulatory submissions requires a careful...

Global Clinical Trial Lab Services

Content provided by Q² Solutions | 01-Apr-2020 | Product Presentation

As a leading global lab services partner, we provide operational excellence, scientific leadership and innovation through technology. We offer end-to-end...

QPS: Global Custom-Built Research Services

Content provided by QPS | 16-Dec-2019 | Product Brochure

Performing complex studies in special populations with remarkable agility. Clinical research just got better with QPS’ Custom-Built Research Services....

Outsourcing Analytical Testing for Biologics - A CRO's Perspective

Content provided by Frontage Laboratories | 01-Dec-2019 | White Paper

Biologics are complex large molecules derived from living organisms or manufactured from cells, and they have inherent structural heterogeneity. Indeed,...

How to Avoid Surprises in Small-Molecule Drug Development Programs

Content provided by Frontage Laboratories | 01-Oct-2019 | White Paper

Over the years, the pharmaceutical industry has made steady progress in improving the safety of drugs in development. Consequently, in 2015, only 14 percent...

Validating The Simoa Technology

Content provided by Frontage Laboratories | 01-Oct-2019 | White Paper

Frontage is the first and only laboratory to validate Quanterix’ Simoa HD1 Analyzer for performing immunoassays. Most of the advanced instruments used...

Assessing Pre-Existing Antibodies in Biotheraputic Development

Content provided by Frontage Laboratories | 21-Aug-2019 | White Paper

Immunogenicity is the leading reason that biologics fail in clinical trials, and thus it has become imperative for drug development programs to include...

The Truth about Physician Referrals and Clinical Trials

Content provided by BBK Worldwide | 24-Jul-2019 | White Paper

Despite growing evidence, the myth that physicians won’t refer patients to clinical trials persists, perpetuated by the belief that they fear losing their...

Survey Report: State of the global pharmaceutical contract services industry 2018

Content provided by William Reed | 11-Jul-2018 | Research Study

In May 2018 Outsourcing-Pharma.com, in association with InnovoCommerce, conducted its second annual ‘state of the industry’ survey on its user base of...

Leveraging Best Practices in Primary Packaging

Content provided by Catalent | 05-Mar-2018 | White Paper

When planning a clinical trial, overlooking the importance of primary packaging can be a mistake. From stability concerns to labeling to patient compliance...

The Power to Make, A Virtual Tour

Content provided by Althea | 24-Mar-2017

You have the power to make a difference. To make new therapeutics that improve quality of life and inspire a healthier world. To do this, you need a manufacturing...

FOR SALE/LEASE CRO/MRO turn key Research Campus, labs, vivariums, OR, archives, offices

Content provided by Northstar Private Capital LLC | 09-Aug-2016 | Product Brochure

Chazy, New York is located only six miles from the Canadian Border in Upstate New York. It is only ten minutes North of Plattsburgh, one hour south of...

What do you need to know about Direct-To-Patient

Content provided by World Courier | 18-Apr-2016 | White Paper

In the world of clinical trials, one of the greatest challenges to overcome is the recruitment and retention of qualified patients. Finding patients who...

IN NEUROLOGY, RARE DISEASES ARE NOT SO RARE

Content provided by QPS | 18-Apr-2016 | Product Brochure

In recent years, society as well as pharmaceutical and biotech industries have gained interest in rare diseases. As a consequence increasing research efforts...

Can patient-centric innovation transform PV

Content provided by Sciformix | 08-Mar-2016 | White Paper

The importance of Pharmacovigilance (PV) as a science and its role in effective patient care in clinical practice and public health is growing. Patient-centeredness...

Alliance for Clinical Trials in Oncology Foundation Selects Oracle Health Sciences Cloud Solutions

Content provided by Oracle Health Sciences | 25-Feb-2016 | Case Study

Alliance for Clinical Trials in Oncology Foundation, a nonprofit organization that supports the mission to reduce the impact of cancer, has selected multiple...

MPI Research Going Further For You

Content provided by MPI Research | 12-Oct-2015 | Research Study

The best way to support our troops is to help them come home healthy. Over 52,280 United States service members were wounded in action during the conflicts...

How technology fights the challenges of clinical trials

Content provided by World Courier | 12-Oct-2015 | Case Study

Two of the biggest challenges in today’s global clinical trials are patient recruitment and retention. These problems often spring from clinical trial...

Single-Use Practices for Cleanroom Fluid Transfer

Content provided by AdvantaPure® | 21-Sep-2015 | White Paper

Pharmaceutical and biopharma manufacturers must transfer fluids from room to room quickly with maximum productivity and minimal effort and expense. By...

Top three reasons to go further with MPI Research

Content provided by MPI Research | 07-Sep-2015 | Case Study

Cardiovascular disease, which includes coronary and peripheral artery disease, stroke,myocardial infarct and congestive heart failure, continues to be...

Ten Tips for Single-Use Pharma Tubing Selection

Content provided by AdvantaPure® | 22-Jun-2015 | Application Note

Tubing used in biopharmaceutical applications has particular requirements. Among them are the ability to withstand sterilization processes, the delivery...

How Molded Manifold Assemblies Prevent Leaks

Content provided by AdvantaPure® | 08-Jun-2015 | White Paper

Pharmaceutical fluid transfer involves many tubing-to-fitting connections, and unfortunately those connections can leak and result in contamination, production...

How Sponsors and CROs Benefit From EDC Efficiencies

Content provided by Merge eClinical | 01-Apr-2015 | White Paper

Intense competition in the prescription drug market is driving pharmaceutical companies to expedite their drug discovery and development processes. Pharmaceutical...

The whole blood assay: Detection of broad spectrum of pyrogens & examples of medical device testing

Merck KGaA, Darmstadt, Germany | Recorded the 09-Apr-2015 | Webinar

Pyrogens in pharmaceuticals, medical devices, biotherapeutics and cosmetics can cause fevers in humans and are potentially life-threatening. Yet standard...

Temperature-Controlled IMP Distribution Challenges

Content provided by Almac Group | 04-Aug-2014 | White Paper

UNDERSTANDING THE CHALLENGES OF TEMPERATURE CONTROLLED INVESTIGATIONAL MEDICINAL PRODUCT DISTRIBUTION IN EMERGING MARKETSTemperature deviation within the...

Learn the risk factors of metabolic syndrome and the role central labs play in aiding its detection

Content provided by ACM Global Central Laboratory | 17-Jun-2014 | Clinical Study

Metabolic syndrome, a serious condition impacting adults and children in all genders, races and ethnicities, can lead to fatal outcomes if not detected...

Fast and Flexible – Early Phase Manufacturing

Content provided by Patheon Inc | 05-May-2014 | Case Study

Early-stage manufacturers of oral solid dosage forms need to be fast and flexible to generate development pathways that can cope with variable API characteristics...

Orthotopic Brain Tumor Models Improved with Imaging

Content provided by Molecular Imaging Inc. | 14-Apr-2014 | Data Sheet

Know more: enhance in vivo pharmacology with imaging. Recent tumor model development and informative imaging technologies have enabled the efficient and...

Footprint-Free™ Cell Line Engineering Services at Transposagen

Content provided by Information not available | 13-Feb-2014 | White Paper

Altering the genome of cells is a powerful and increasingly necessary tool for drug discovery and research. Transposagen utilizes its expertise and a diverse...

Controlled Release and Bioavailability Enhancement

Content provided by Information not available | 28-Oct-2013 | Case Study

Metrics provides product development that leverages proprietary pharmaceutical technologies in the areas of: •    Customized Controlled Release Drug Delivery...

Biosimilars – Landmark Developments Point to the Future for Regulations and Analysis

SGS Life Science Services | Recorded the 09-Oct-2013 | Webinar

2013 is a landmark year for biosimilars, with the approval of the first biosimilar mAb and regulatory developments across the globe. Correctly interpreting...

(b)(2) or not (b)(2)? That is the question.

Content provided by Camargo Pharmaceutical Services | 19-Aug-2013 | White Paper

505(b)(2) is more than a regulatory pathway - for many, it’s a unique strategy that can often result in product approval with lower risk, reduced development...

ePathology Improves Data Accuracy & Study Productivity! – Amicus Study Confirms

Content provided by Aperio | 20-Mar-2013 | White Paper

With current glass slide methods, sharing and scoring slides within a study from one pathologist to another at a different organization or site, meant...

Quantify biodistribution, enhance in vivo decisions

Content provided by Molecular Imaging Inc. | 04-Feb-2013 | Data Sheet

Non-invasive preclinical SPECT imaging of test agent biodistribution, kinetics and targeting in discovery and safety applications has key advantages over...

Biomarkers of Toxicity Panel in Clinical Trials

Content provided by ACM Global Central Laboratory | 18-Sep-2012 | White Paper

Most drug candidates are discontinued because of induced organ toxicity and half of them owe this to liver toxicity. This issue explains why drug developers...

Utility of FDG PET in Drug Development

Content provided by Molecular Imaging Inc. | 20-Aug-2012 | White Paper

Imaging metabolism with FDG PET offers reliable and clinically translatable biomarkers for evaluation of candidate compounds. It can also:Provide a reliable...

Novel Biomarkers for Diabetic Nephropathy

Content provided by Pacific Biomarkers, Inc. | 18-May-2011 | White Paper

Type 2 diabetes is the major cause of end-stage renal disease. In the present decade, 30% of the predicted $1.1 trillion medical costs of dialysis world-wide...

Guiding Development of Novel Drugs

Increased use of therapeutic proteins such as monoclonal antibodies, engineered proteins and other biological products has resulted in a growing number...

Reducing Dosing Errors in Preclinical GLP Infusions

Content provided by Solomon Scientific | 09-Feb-2011 | White Paper

The White Paper explains that the Orchesta™ Automated Infusion System from Solomon Scientific reduces dosing error opportunities by 99% in preclinical...

Incretins & gastrointestinal hormones

The digestion and absorption of nutrients subsequent to food intake is associated with increased secretion of multiple gastrointestinal (GI) peptides....

Approaches to Analyzing Therapeutic Peptides and Proteins by LC-MS/MS

Content provided by Covance | 14-Dec-2010 | White Paper

Covance is committed to delivering world class service, expertise and efficiency to support your drug development needs. In the attached white paper, read...

Generate Sales Leads: Free White Paper

Content provided by William Reed | 02-Aug-2010 | White Paper

White papers (or technical papers) are one of the most effective ways to generate leads for your sales team and establish your company’s reputation as...