Processing equipment

Quartic.ai, Sparta Systems partner on ‘smart’ manufacturing tech

14-Jul-2020 By Jenni Spinner

The two companies are collaborating on AI-enabled risk detection, intended to increase pharma product quality and process efficiency.

A-Alpha Bio lands Gates Foundation drug development grant

13-Jul-2020 By Jenni Spinner

The $800K grant will fund development of therapeutics for infectious diseases, including respiratory viruses like COVID-19, using machine learning.

ChargePoint butterfly valve safely handles APIs

29-Jun-2020 By Jenni Spinner

The company’s PharmaSafe containment split butterfly valve is designed for safe handling of non-sterile API and formulation ingredients.

FDA advises API makers on COVID-19 safe practices

24-Jun-2020 By Jenni Spinner

The agency's latest guidance offers advice on keeping manufacturing of active pharmaceutical ingredients safe during the COVID-19 pandemic.

Romaco Kilian unveils high-speed tablet press

12-May-2020 By Jenni Spinner

The double-sided S 710 Prime rotary press is designed for compressing single- and dual-layer tablets, promising high productivity.

Pharma Integrates

Pfizer’s ‘long and complex’ journey to continuous manufacturing

27-Nov-2019 By Vassia Barba

‘Accelerate, accelerate, accelerate’ – a Pfizer executive explains how the integration of continuous manufacturing helped the company deliver drugs to patients faster.

Heraeus adds ‘much-needed’ capacity for chemo components manufacture

25-Nov-2019 By Vassia Barba

Heraeus adds production line to expand its capacity for the manufacture of platinum-based HPAPIs.

CPhI Worldwide 2019

Exothermic reactions at -60°C for continuous API manufacture

11-Nov-2019 By Vassia Barba

Driven by market demand, De Dietrich develops an API production set that enables continuous manufacturing of molecules that require exothermic chemical reactions.

Embracing the digital world for optimised drug manufacturing

30-Oct-2019 By Vassia Barba

In-PharmaTechnologist steps inside Siemen's Digital Experience Centre to learn about the digital services that aim to transform the manufacturing of pharmaceuticals.

GSK and AZ on continuous manufacturing platform ‘grand challenge’

14-Oct-2019 By Vassia Barba

A consortium between CPI and the University of Strathclyde aims to create a direct compression platform for continuous manufacturing of oral solid dosage drugs.

‘This case is about the color purple’: GSK’s suit against Sandoz refuted

07-Oct-2019 By Ben Hargreaves

England’s High Court throws out the claim that Sandoz’s inhaler product passed off the appearance of GSK’s rival through its use of the color purple in packaging.

The five potential sources of nitrosamine contamination

02-Oct-2019 By Ben Hargreaves

With nitrosamines back in the headlines due to the recent discovery of contaminants in ranitidine, the EMA releases the five potential causes of the impurities plaguing the industry.

Merz completes construction of new plant and filling line

17-Sep-2019 By Ben Hargreaves

Merz announces that it has completed the construction of a new plant for its botulinum neurotoxin product and unveils a ‘robot-controlled’ filling line.

Mallinckrodt agrees to sell CDMO business for $250m

11-Sep-2019 By Ben Hargreaves

Amid opioid lawsuits, Mallinckrodt looks to slim down its overall business by agreeing the sale of BioVectra to HIG.

Urovant ramps up spending on Codexis ingredient ahead of commercial production

13-Aug-2019 By Nick Taylor

Urovant Sciences’ preparations to file for US approval of vibegron add to Codexis’ sales in the second quarter.

Product Innovations

Single-Pass Tangential Flow Filtration

Tangential flow filtration (TFF) is widely used in the biopharmaceutical industry for downstream processing applications. Typical TFF steps concentrate...

Seed Train Intensification Using High Cell Density Cryopreservation and Specially-designed Expansion Medium

Upstream processes can be intensified using a number of strategies which can deliver significant improvements in speed, flexibility and reliability. In...

Process Optimization and Scalability Evaluation of Pellicon® Capsules for Single-Pass Tangential Flow Filtration of mAb-Based Biomolecules

Single-pass tangential flow filtration (SPTFF) is a method of ultrafiltration for the purposes of either volume reduction or protein concentration. This...