Tabletting, coating & ancillary equipment

Measuring the Disintegration Force Development of Tablets Containing Different Disintegrants

JRS PHARMA | 29-Oct-2022 | Technical / White Paper

The aim of this study was to investigate the disintegration behavior of croscarmellose sodium (CCS), sodium starch glycolate (SSG) and crospovidone (PVPP).

The Performance of PROSOLV® EASYtab SP in 4 Medium-Dose, Direct Compression Formulations

JRS PHARMA | 30-Sep-2022 | Technical / White Paper

In the present study, the performance of PROSOLV® EASYtab SP was tested in four DC formulations with different model APIs.

The Effect of PVP Viscosity on the Binding Performance in Naproxen Tablets

JRS PHARMA | 01-Aug-2022 | Clinical Study

This study aimed to compare the performance of VIVAPHARM® PVP K25, VIVAPHARM® PVP K30, and VIVAPHARM® PVP K90 respectively as wet-granulation binders in...

Discover the endless opportunities our Softgel Capsule can offer to your brand.

Softigel by Procaps | 17-Mar-2022 | Product Catalog

The softgel capsule has been on the market since the 19th century evolving to the present day. Because of this, consumers feel familiar with the technology...

How Can a Supply Chain Dashboard Yield Greater Clinical Trial Insights, Cost Control, and Efficiency?

Ancillare | 10-Jan-2022 | Technical / White Paper

With 1 in 10 Sponsors identifying a lack of technology integration as their biggest pain point, Deighton Liverpool, Ancillare’s Chief Information Officer...

SOFTIGEL: an integrated CDMO in Softgel technologies

Softigel by Procaps | 12-Jul-2021 | Press Release

Together again, where innovation takes place: Meet with Softigel ® by Procaps during CPhI North America 2021

Unlocking the Power and Versatility of Plant-Based Softgels

Softigel by Procaps | 23-Mar-2021 | Product Brochure

While plant-based diets continue to grow in popularity, the desire to live and act more sustainably and healthfully is on the rise.

How to resolve sticking issues in tablet production

I Holland Limited - Tabletting Science | 24-Jun-2019 | Case Study

Tablet sticking is one of the most common problems in tablet manufacture. Find out how I Holland used the TSAR scientific predictive model and expert tablet...

Fill Release at the Right Time in the Right Place

Gelita AG | 19-Sep-2018 | Technical / White Paper

From rapid release in the stomach for e.g. analgesics to enteric release for fills with unpleasant aftertaste – GELITA delivers the respective gelatine...

Helping to speed your product to market and gain efficiency

Colorcon Inc. | 22-May-2018 | Data Sheet

With a commitment to provide best-in-class solutions, Colorcon's Solid Dose newsletter brings you the latest insight to support your development and...

Customized Fill Release in Gelatine Soft Capsules

Gelita AG | 07-May-2018 | Application Note

From rapid release in the stomach for e.g. analgesics to enteric release for fills with unpleasant aftertaste – GELITA delivers the respective gelatine...

Roquette Oral Dose Case Study - Part IV

Roquette Pharma Solutions | 04-Dec-2017 | Case Study

Download the latest Roquette case study and learn more on how PEARLITOL® Flash mannitol and starch compound offers inert stability, fast disintegration...

Roquette Oral Dose Case Study - Part III

Roquette Pharma Solutions | 27-Nov-2017 | Case Study

Download the Case Study to find out how Roquette’s SweetPearl® P 300 DC maltitol technology makes an effervescent tablet solution attractive and palatable...

Roquette Oral Dose Case Study - Part II

Roquette Pharma Solutions | 06-Nov-2017 | Case Study

Download the case study and learn more on how Roquette’s taste masking technology KLEPTOSE® Linecaps (KL) allows the delivery of an efficient taste masking...

The Solid Dose, Latest News from Colorcon

Colorcon Inc. | 06-Nov-2017 | Data Sheet

With a commitment to serve customers through product innovation and technical excellence, Colorcon's Solid Dose newsletter brings you the latest insight...

Roquette Oral Dose Case Study - Part I

Roquette Pharma Solutions | 06-Nov-2017 | Case Study

Download the Case study and learn more on ReadiLYCOAT®: Immediate release film coating system for heat sensitive oral dosage forms is a breakthrough in...

Optimizing vessel geometry for mag drive agitators

Steridose, Inc | 14-Sep-2017 | Technical / White Paper

The performance of a bottom mount magnetically driven agitator (mag drive mixer) is heavily dependent on its relationship with the vessel’s geometry, baffles,...

Increase tablet production with multi-tip tools

I Holland Limited - Tabletting Science | 01-Jun-2017 | Technical / White Paper

Multi-tip punches increase the number of tablets produced per turret rotation, which increases production rates of existing presses.This tooling has transformed...

First-in-Human Development Strategies

Catalent Pharma Solutions | 01-May-2017 | Insight Guide

Crucial and cost-effective factors to consider when transforming a pre-clinical development compound into a first-in-human, early-phase drug candidate....

Taking fill release rates to a new level

Gelita AG | 20-Mar-2017 | Technical / White Paper

Various attempts by the pharmaceutical industry to reduce cross-linking with additives have only been partially successful. GELITA, however, followed another...

HOW TO MAXIMISE TOOLING LIFE SPAN & PRODUCTIVITY THROUGH PLANNED PROFESSIONAL MAINTENANCE

I Holland Limited - Tabletting Science | Recorded the 02-Mar-2017 | Webinar

Tablet punches and dies are often viewed as consumable items that can be replaced at relatively low cost. However, with the constant challenge of increased...

A unique pharmaceutical oil for solubility and oral bioavailability enhancement

Gattefossé | 01-Oct-2016 | Technical / White Paper

This white paper features Maisine® CC, Gattefossé’s tradename for glyceryl monolinoleate (USP-NF), also known as corn oil mono-, di- and triglycerides....

Time and cost savings in pharmaceutical production with high performance equipment cleaning after processing EUDRAGIT® coatings

Evonik Health Care | Recorded the 25-Oct-2016 | Webinar

The cleaning of coating equipment for pharmaceuticals can make up a significant portion of production costs, particularly in commercial-scale processes....

Maintain in-use product integrity with specialty film coating

Colorcon Inc. | 12-Jul-2016 | Case Study

The drug combination of amoxicillin and clavulanic acid is moisture sensitive, demanding low humidity manufacturing and moisture barrier packaging. This...

New Organic Coating System to Modulate Drug Release

Colorcon Inc. | 09-May-2016 | Technical / White Paper

A Colorcon Study, Effect of Coating Weight Gain and Pore-Former Level on Drug Release with a Fully Formulated Ethylcellulose Barrier Membrane Coating System,...

Human study: gelatin & HPMC capsule bioequivalence

Capsugel | 04-May-2016 | Technical / White Paper

Rapid and consistent in-vivo drug dissolution is critical for drug absorption. However, in-vitro dissolution results do not always correlate with the in-vivo...

White paper: ensure quality in novel dosage forms

Stable Micro Systems | 14-Mar-2016 | Technical / White Paper

From oral sprays to pastilles and capsules, pharmaceutical products must increasingly cater for a wider range of preferences. Download this free white...

Next Generation HPMC Capsules: Bioequivalence and Functional Performance

Capsugel | Recorded the 17-Feb-2016 | Webinar

Two-piece hard shell capsules made from hydroxypropyl methylcellulose (HPMC) are emerging as an alternative to conventional gelatin capsules for oral drug...

Tablet Coating at Low Bed Temperatures with a Novel Coating Polymer

Roquette Pharma Solutions | 11-Jan-2016 | Case Study

This study shows how to obtain elegant, uniform coatings with zero visible defects and a practical coating solution for heat sensitive products!

Leveraging ADVASEPT® Technology

Catalent Pharma Solutions | 14-Dec-2015 | Case Study

Catalent’s ADVASEPT® Technology is an advanced aseptic manufacturing process that leverages blow-fill-seal (BFS) technology to create a glass free container...

API moisture sensitive? Get Tablet Stability Under Control

Colorcon Inc. | 17-Nov-2015 | Technical / White Paper

Looking for ways to increase confidence for your final product stability when moisture sensitivity of the active in your formulation is a concern?  Great...

I Holland Troubleshooting Seminar 2015

I Holland Limited - Tabletting Science | 01-Sep-2015 | Event Programme

It’s that time of year again and our ever popular training seminar is just around the corner. It is designed to identify and address common problems during...

Maintain Product Integrity with Moisture Protection

Colorcon Inc. | 01-Jun-2015 | Technical / White Paper

Many active pharmaceutical ingredients and solid oral dosage tablets are sensitive to moisture, potentially resulting in degradation or poor product performance....

I Holland: Sharing our knowledge and experience

I Holland Limited - Tabletting Science | 01-Feb-2015 | Event Programme

Maintenance training, seminars, our 7 Step Audit SOP and live webinars are a just few of the training opportunities I Holland have to offer. Click to find...

Customized Biosimilarity Analytical Testing from Catalent

Catalent Pharma Solutions | 26-Jan-2015 | Technical / White Paper

Assessment of biosimilar molecules requires an orthogonal analytical approach.  Any one particular analytical technique is not able to fully define the...

OptiPact™ Technology Introduced by Catalent

Catalent Pharma Solutions, the leading global provider of advanced delivery technologies and development solutions for drugs, biologics and consumer health...

Sticking Problems with Tabletting Science

I Holland Limited - Tabletting Science | 01-Dec-2014 | Data Sheet

TSAR≈PREDICT accurately forecasts the correct anti-stick PharmaCote® coating solution for your formulation. It calculates single particle adhesion to the...

Punchline – Latest news from I Holland

I Holland Limited - Tabletting Science | 01-Aug-2014 | Case Study

Welcome to the Summer 2014 edition of PunchLine, I Holland’s newsletter for tablet manufacturing professionals. This issue sees us conclude our TSAR (Tabletting...

It’s True: Correct Use Of Ultrasonic Cleaning Really Can Reduce Cleaning Time By More Than 50%

I Holland Limited - Tabletting Science | 01-Jul-2014 | Case Study

The Raybond company, located in Saint Louis (France), specialises in bonding solutions that are mainly used to secure fastenings on windows and windscreens...

A better understanding on gelatin cross-linking: causes, control strategy and regulatory approaches

Softigel by Procaps | Recorded the 17-Jul-2014 | Webinar

Gelatin is a water-soluble protein material that is extensively used in several applications, including food, pharmaceutical and photography, among others....

Do you have spores?

Steris: A global leader in infection prevention and contamination control | 27-May-2014 | Technical / White Paper

Trending analysis of cleanroom environmental monitoring data sometimes shows the presence of spores. These undesirable microbes must be eradicated quickly...

Smart strategies for sustained release matrix tablets: Compritol® 888 ATO

Gattefossé | 19-May-2014 | Technical / White Paper

This white paper gives an overview of how Compritol® 888 ATO provides clinically relevant sustained drug release profiles along with biopharmaceutical,...

Excipients for Multilayer Tablets

JRS PHARMA | 07-May-2014 | Technical / White Paper

Multi-layered tablets bring together differently formulated powder mixtures, which typically contain different APIs, into a single tablet with two or more...

‘TSAR≈Predict’ Solves Sticking Problems in Hours

I Holland Limited - Tabletting Science | 02-May-2014 | Data Sheet

‘TSAR≈Predict’ is a revolutionary new service which will put an end to time consuming and expensive field trials by offering a solution to stop tablet...

PharmaCare® 7 Step Audit and Standard Operating Procedure

I Holland Limited - Tabletting Science | 01-May-2014 | Data Sheet

Tablet compression tools are often viewed as consumable items but I Holland believe that just because they are replaceable they shouldn’t be viewed as...

Embedding Q and R Practice in Pharma Ingredient Manufacture

Corbion | 09-Dec-2013 | Technical / White Paper

A growing amount of Q&R applies to creating pharmaceuticals. Pharmaceutical manufacturers prefer ingredients developed with compliance that exceeds...

NEOBEE® MCTs Enhance Pharmaceutical Bioavailability

Stepan Lipid Nutrition | 04-Nov-2013 | Technical / White Paper

An efficient solvent for many lipophylic drugs and vitamins, NEOBEE® MCTs emulsify in aqueous environments and help uptake in intestinal cells. They are...

Rexam’s new child-resistant ophthalmic and nasal closure : continuing many decades of innovative child-resistant drug packaging

Rexam Healthcare | 15-Oct-2013 | Data Sheet

The U.S. Consumer Product Safety Commission (CPSC) requires child-resistant (CR) packaging for all products containing imidazolines (vasoconstrictor drugs)....

Improving API Stability with Increased Excipient Purity

Croda Inc | 14-Oct-2013 | Data Sheet

Sensitive or unstable APIs can pose formulating challenges when it comes to ensuring their consistent and safe delivery.  Data indicate that the purity...

Enhancing Actives Delivery for Optimal Formulation Efficacy

Croda Inc | 05-Aug-2013 | Data Sheet

Excipients designed to enhance skin penetration can maximize the efficacy of topical formulations.  Through lipid disruption and skin polarity modification,...