Tabletting, coating & ancillary equipment

NEWS IN BRIEF

Hovione expands production capacity of oral dosage forms

12-Nov-2018 By Ben Hargreaves

The Portuguese CDMO has announced plans to improve production capacity by bringing in commercial scale equipment for blending, tabletting and coating.

Sun Pharma adds $1.6m sterile manufacturing line in Guwahati, India

15-Oct-2018 By Flora Southey

Sun Pharma has installed a parenteral drug production line in Guwahati for the manufacture of sterile products.

CPhI Worldwide 2018

CPhI 2018: Dispatches from Madrid

11-Oct-2018 By Flora Southey

Following stints in Paris and Frankfurt, CPhI Worldwide has again set up in Madrid for three days of insight briefings, biopharmaceutical tracks and networking.

CPhI Worldwide 2018

Ashland launches film coating tech in response to ‘continuous' demand

09-Oct-2018 By Flora Southey

The Aquarius Genesis film coating system is specially designed for continuous manufacturing, but can also be applied to batch processes, says executive.

Small CDMO targets SMEs with spray drying tech in Spain

03-Oct-2018 By Flora Southey

As a relatively small CDMO, Idifarma fits better with small and medium size companies’ goals, costs and flexibility, says executive.

Lonza stresses ‘flexibility’ advantages on launch of Capsugel Colorista

06-Sep-2018 By Ben Hargreaves

Lonza launched its Capsugel Colorista product, which means it can now produce capsules in 150 colour options.

Boehringer begins construction at €85m tablet manufacture plant

29-Aug-2018 By Ben Hargreaves

Boehringer Ingelheim has begun construction of a new production facility for drugs in tablet form, with an expected completion date of 2020.

SI Group increases ibuprofen manufacture by 35% amid global shortage

09-Aug-2018 By Ben Hargreaves

SI Group announced that it will be increasing its capacity for ibuprofen manufacture by 25%, to be completed by 2020.

3D printing brings novel doses, shapes and characteristics to ‘advanced manufacturing’, states Aprecia

19-Jul-2018 By Ben Hargreaves

The US FDA has drawn industry attention to the potential of 3D printing and continuous manufacturing, which it says could “improve drug quality, address shortages of medicines, lower drug costs, and bring pharmaceutical manufacturing back to the US”.

Formulations for sale: Noramco and SPI Pharma target drugmakers with scalable tech

26-Apr-2018 By Flora Southey

Noramco and SPI Pharma have partnered to offer ‘ready-to-implement’ formulations for branded and generic drugmakers.

Mayne Pharma opens $80m facility, expands CDMO offering

19-Apr-2018 By Melissa Fassbender

Mayne Pharma has opened a new 126,000-square-foot oral solid-dose manufacturing facility to meet demand driven by new product launches – and new revenue stream from its CDMO business.

Making the switch: L.B. Bohle talks longterm benefits of continuous manufacturing

10-Apr-2018 By Flora Southey

Having the right company mindset is key when switching from batch manufacturing to the continuous method, says equipment vendor L.B. Bohle.

Spanish CDMO ups spray drying services for highly potent drugs

29-Mar-2018 By Flora Southey

Idifarma says it will boost its spray drying services for highly potent drugs in response to growing client demand.

Hanmi invests in ‘smart plant’ to boost CDMO biz

29-Mar-2018 By Staff Reporter

South Korean firm Hanmi Pharmaceutical has invested 150bn won ($140.7m) in a manufacturing ‘smart plant’ to increase its contract services.

Romaco launches wax and fat coating hot melt machine

27-Mar-2018 By Staff Reporter

Romaco Group has launched a machine for coating pharmaceutical products with hot fats and wax it says can reduce hot melt processing times by 85%.

Novartis: ‘Time is right’ for $13bn consumer health sale to GSK

27-Mar-2018 By Dan Stanton

Novartis will sell its stake in a consumer healthcare joint venture to partner GSK and plans to invest the $13bn into its core pharmaceutical businesses.

Upperton upping spray-dry production in $2m relocation

15-Mar-2018 By Staff Reporter

Spray-drying service provider Upperton Pharma Solutions has expaned to offer GMP manufacturing for early-stage clinical trials.

Capsule maker ups track and trace with molecular tagging

14-Mar-2018 By Flora Southey

ACG says adding Applied DNA Sciences’ molecular tagging and authentication technology to its capsule products will increase supply chain security.

News in Brief

Clariant raising colouring costs

12-Mar-2018 By Staff Reporter

Clariant will raise the prices across its Masterbatch range by up to 7% from April.

No chewing, grinding or snorting: Recipharm adds Altus anti-abuse tech

06-Mar-2018 By Dan Stanton

A license agreement will allow Recipharm to offer its customers Altus Formulation’s INTELLITAB and FLEXITAB anti-abuse drug delivery technologies.

Latest GMP crackdown leaving ‘naive’ cosmetic firms with FDA warnings

06-Mar-2018 By Dan Stanton

Increased enforcement of cGMP on over-the-counter (OTC) drugs is highlighting the grey-area in classification with cosmetic products, a former FDA director says.

Fake news? Novartis confirms it has no plans to sell Sandoz

26-Feb-2018 By Dan Stanton

Novartis is considering divesting non-core and negative margin products but confirms it has no plans to place Sandoz “on the auction block.”

Lonza ups HPAPI encapsulation capacity in Florida

22-Feb-2018 By Staff Reporter

Lonza has increased its encapsulation capacity and invested in highly potent active pharmaceutical ingredient (HPAPI) services at a facility in Tampa, Florida.

USV receives FDA close-out at Indian plant

20-Feb-2018 By Staff Reporter

The US FDA has lifted a warning at an Indian oral solid dose manufacturing facility run by USV Private Limited.

Slippery when wet: Colorcon coating aims to ease tablet swallowing

20-Feb-2018 By Dan Stanton

Colorcon has created a coating system it says makes swallowing tablets easier, fulfilling patient compliance demands in recent regulatory guidance.

Sandoz cuts 65 jobs in first stage of Colorado plant closure

12-Feb-2018 By Dan Stanton

The first round of job cuts at a solid oral dose facility in Broomfield, Colorado earmarked for closure has taken place, says Novartis subsidiary Sandoz.

Nordic project takes ‘manufacturing-on-demand’ approach to future drugs

07-Feb-2018 By Dan Stanton

Nordic Universities will investigate 3D printing, electrospraying, and microfluidics in an industry supported collaboration aimed at revolutionising production in an age of personalised medicine.

Lonza: Capsugel contributes to ‘record year’ for Swiss CDMO

01-Feb-2018 By Dan Stanton

Lonza has attributed a record-breaking year to the addition of Capsugel along with continued high pharma and biotech demand.

Hovione adds inhalation product development tech at former Generis site

30-Jan-2018 By Staff Reporter

Hovione has bolstered its encapsulation for inhaled products technology capabilities at its site in Portugal.

Emergent eyes capacity boost for anti-nerve gas auto-injector

11-Dec-2017 By Dan Stanton

Emergent BioSolutions says it is looking to expand auto-injector manufacturing capacity due to growing demand for its nerve agent antidote product Trobigard.

News in Brief

Piramal buys GI OTC brand, Shreya wins manufacturing contract

30-Nov-2017 By Staff Reporter

Shreya Lifesciences will continue manufacturing Digeplex after selling the gastro-intestinal (GI) drug to fellow Indian drugmaker Piramal Enterprises.

News in Brief

US FDA inspection lands Glenmark with 483 with seven observations

28-Nov-2017 By Dan Stanton

Glenmark has received a US FDA Form 483 with seven observations at its Baddi finished formulations facility in Baddi, India.

Fresenius Kabi investing $100m and adding 445 jobs in North Carolina

22-Nov-2017 By Dan Stanton

Encouraged by a North Carolina state grant, Fresenius Kabi will expand its prefilled syringes business acquired from Becton, Dickinson and Company in 2016.

CPHI WORLDWIDE 2017

Continuous manufacturing: suitable excipients & more knowledge required, says Dow

25-Oct-2017 By Flora Southey

Drug firms need excipients suited to continuous manufacturing according to Dow, which says a better understanding of how products perform when used in round-the-clock production is required.

Recipharm kits out Lisbon plant in latest stage of serilization tech roll out

23-Oct-2017 By Gareth Macdonald

Recipharm has installed serialization technology at its contract production facility in Lisbon, Portugal citing impending US and EU rules as a driver for the investment.

Pfizer expands Japan contracting offering touting market knowhow

22-Oct-2017 By Gareth Macdonald

Pfizer has expanded its contract manufacturing offering in Japan, adding capacity to make highly potent solid dosage forms at its facility in Nagoya.

Avara buys French site: AZ talks what, why and where to next

10-Oct-2017 By Flora Southey

Following the announced sale of AstraZeneca’s solid dose facility to Avara, the former outlines the Reims, France-based sites capabilities, and tells us why it is letting it go.

update

Pfizer confirms Puerto Rico plants damaged by hurricane Maria

26-Sep-2017 By Gareth Macdonald

Communication difficulties are hampering drug industry efforts to assess damage to manufacturing operations caused by the hurricane that struck Puerto Rico last week.

Roche Spanish plant becomes eighth solid dose site for Recipharm

20-Sep-2017 By Dan Stanton

Recipharm has acquired a Spanish manufacturing plant and signed a supply deal with former owner Roche for a range of solid dose products worth €35m a year.

Puracap's Wuhan site passes US FDA inspection prompted by ANDA

19-Sep-2017 By Staff reporter

US regulators are satisfied a soft gelatin capsule plant in Wuhan, China is up to code according to Puracap Pharmaceutical LLC.

Recipharm to make clinical trial cancer candidate for Kancera

18-Sep-2017 By Dan Stanton

Recipharm will make clinical trial capsules to support oncology candidate KAND567, a former AstraZeneca Fractalkine receptor inhibitor being developed by Kancera.

Update

Single shot in 'tiny coffee cups’ could deliver multiple vaccines, MIT

18-Sep-2017 By Dan Stanton

3-D microparticles which degrade at differing rates in the body could allow multiple doses of drugs or vaccines to be administered in a single injection, say MIT researchers.

BMS inks $105m deal to access Halozyme drug delivery tech

14-Sep-2017 By Dan Stanton

Bristol-Myers Squibb will also make up to $160m in milestone payments for each candidate developed using Halozyme Therapeutics’ large-volume biologics delivery platform.

No fraud, no conspiracy, no error: France and Merck say reformulated Euthyrox is safe

12-Sep-2017 By Gareth Macdonald

A new formulation of Euthyrox linked to a surge in adverse event reports in France is safe, effective and more consistent than the older version of the drug say ANSM and Merck.

Oramed looking for commercialisation partner for oral insulin in US

06-Sep-2017 By Dan Stanton

Oramed is eying up commercial partnerships for its oral insulin candidate following a positive meeting with the US FDA to discuss an appropriate approval pathway.

Vial-up: Althea adds fill/finish capabilities in California

31-Aug-2017 By Staff Reporter

A vial filling line at Ajinomoto Althea’s manufacturing site in San Diego will maximise yield and reduce product loss, the CMO says.

Dissolution testing and dirty gaskets: US FDA warns Hetero Labs

30-Aug-2017 By Dan Stanton

The US FDA has sent a warning letter to Hetero Labs Limited citing GMP violations at its finished dose formulations facility in Telangana, India.

Catalent looking to parenteral dosage form capability for future expansion

29-Aug-2017 By Dan Stanton

Catalent says it will focus its M&A strategy to fill the injectables capability gap in its CDMO offering.

Micro-Sphere pumps $22m into capsule filling facility

23-Aug-2017 By Flora Southey

Spray drying and capsule filling-focused Micro-Sphere is expanding manufacturing capabilities at its facility in Ticino, Switzerland.

Hikma upping injectables capacity by as much as 500% by end of 2017

22-Aug-2017 By Dan Stanton

Hikma has ramped up capacity at manufacturing facilities in the US and Portugal manufacturing to meet the growing demand for its lyophilised and oncology products.