US group Aptuit has bolstered its chemistry offering with a new solid state chemistry screen that it says will enable better decisions during drug formulation development and process scale-up.
Capsugel says latest addition to its Xcelodose range, Xcelolab, provides a rapid and reproducible solution for dispensing small amounts of pharmaceutical powders during laboratory stage drug development.
The EFCG has welcomed the addition of excipient GMP requirements to the draft amendments of the EU falsified medicines directive but warned that deeper analysis is needed to establish which products warrant further regulation.
Merck KGaA has begun work on a new inorganic salts plant in Darmstadt, Germany, citing growing demand as the main motivation for the €30m ($42m) investment.
Lonza will shut down its API plant in Riverside, Pennsylvania, US by the end of the year as part of a plan to cut costs and shift small-molecule production to Asia.
GEA Pharma Systems has extended its agency agreement with India’s Ace Technologies to include its range of lyophil freeze-dryers in a bid to further open up the market.
BASF says its new Soluplus excipient will help meet demand for solubilising agents that are compatible with hot melt extrusion (HME) manufacturing methods.
The EC’s plan to make excipients comply with GMP is “still alive”, according to Cargill which spoke to in-PharmaTechnologist at CPhI about its Zerose erythritol product that it claims can improve compliance.
Ampac Fine Chemicals (AFC) has added three new commercial-scale Hastelloy liquid-liquid centrifuges to its API making business in a move that, it says, will increase batch size and lower manufacturing costs.
Sweden’s XSpray Microparticles says its new particle plant proves its RightSize tech can be scaled-up for industrial applications and will be a boost for its contract services offering.
US group Cambridge Major Laboratories (CML) will begin transferring API production to its 125,000 sq ft manufacturing plant in Germantown, Wisconsin at the end of next month.
SAFC’s bioscience unit and Sartorius Stedim Biotech (SSB) have teamed up to create a suite of fluid management solutions that they hope will prove irresistible to the booming biomanufacturing sector.
Altus Pharmaceuticals has terminated its contract with Lonza over an alleged breach in the agreement to provide active pharmaceutical ingredients (API) for Trizytek (liprotamase).
Particle Sciences (PSI) is aiming to advance its contract processing offering by collaborating with Microfluidics and sharing formulation and nanotechnology expertise.
Swiss drugmaker Helsinn has unveiled plans to add high-potency API R&D and manufacturing capacity to its facility in Biasca in the south of the country.
Pharmafreight and Kryotrans have teamed up to offer a one-way, temperature-controlled shipping service that they claim will help pharmaceutical exporters cut costs and boost efficiency.
Xspray has doubled its personnel and laboratory space in response to demand for its manufacturing service, which is designed to overcome the drawbacks associated with micronisation.
API maker Hovione’s manufacturing facility in Cork, Ireland was unveiled at an opening ceremony yesterday just two weeks after the previous owner, global drug giant Pfizer, formally handed over the keys.
Chinese contract research provider WuXi PharmaTech slipped to a fourth quarter loss in 2008, despite reporting a strapping 74 per cent increase in sales.
ESS Technologies has extended the range of its Monoblock platform with a new bottle feeder capable of accurately filling and capping up to 120 small pharmaceutical liquid bottles a minute.
Pliva is laying off 790 employees over the next 12 months following its acquisition by Teva but still intends to significantly increase API and finished product output over this period.
Falling API sales and “an unprecedented negative economic environment” have forced Perrigo to cut its fiscal 2009 profit forecast and sent stock plummeting by 20 per cent.
Nitec has received approval in Europe for its rheumatoid arthritis treatment Lodotra making it the first product using SkyePharma’s propriety drug delivery technology Geoclock to come to market.
Quadro Engineering has entered into a partnership to distribute Micro-Macinazione’s Jet-Mill products in the Americas, as well as launching its own API sifter.
The US Food and Drug Administration (FDA) has issued draft guidance on process validation, updating its 1987 document to incorporate advances in manufacturing technology and thinking.
Manufacturers of ingredients used as excipients in pharmaceuticals have faced some regulatory problems with a series substances known as 'atypical actives'.
German chemical giant BASF chose this year’s AAPS meeting in Atlanta, US to showcase its growing library of USP excipient verification certificates, making good on its commitment to apply the highest manufacturing standards to this area of its business.
Cambrex joined a number of its peers in the contract services sector by reporting pressure on third quarter sales and earnings, providing further evidence that outsourcing companies are not immune to the economic downturn.
Isochem will have manufactured ten tonnes of the multi-purpose drug excipient vitamin E TPGS by the end of the year, marking the end of what it says has been a successful first 12 months of commercial scale production.
French firm Novasep has significantly boosted its ability to provide customers with enantiomerically pure compounds with the addition of a new chiral chromatography unit.
Teva and Kowa have set their sights on Japan’s $4.6bn (€3.1bn) generics market with their development and manufacturing joint venture Teva-Kowa Pharma.
Prosonix, a specialist developer of ultrasonic industrial processing solutions, says that global drug giant Pfizer is to begin using its Prosonitron reactor and sonocrystallisation technology at its manufacturing facility in Ireland.
Germany-based Diapharm has launched a service allowing pharmaceutical manufacturers to perform joint third-party audits of active pharmaceutical ingredients (APIs).
Exclusive interview with IPEC China chairman Nevin Cheng
IPEC China must become a “harmonisation bridge between China and other countries,” according to Colorcon’s Nevin Cheng who was recently elected chairman of the new organisation.
in-PharmaTechnologist.com's latest round-up of developments in pharmaceutical manufacturing features news of the world’s “biggest pharmaceutical allergen production unit”, Lentigen’s relocation and a cytotoxic robot.
Codexis and Arch Pharmalabs’ expanded supply and development deal will see the latter produce APIs used in the manufacture of atorvastatin, principal component of Pfizer’s cholesterol buster Lipitor.
Cambrex posted a 5 per cent hike in revenues in the second quarter, helped by its shift into contract controlled substance manufacture, although without favourable currency effects sales would have slipped back 2.6 per cent.
The gulf in rates of growth between emerging and established markets in the biotech active pharmaceutical ingredient (API) sector has been highlighted in a new report from the Chemical Pharmaceutical Generic Association (CPA).
China is on course to having its own version of the International
Pharmaceutical Excipients Council - joining its fellow
organisations in Europe, the Americas and Japan.
With active pharmaceutical ingredient sales of $1,460m (€960.8m) in
2007 and a portfolio of more than 250 compounds, Teva
Pharmaceutical Industries is by a long stretch the dominant
supplier in the global API market.
Bosch Packaging Technology will be rolling out a range of new and
recently launched processing and packaging solutions at the
Interpack 2008 exhibition in Düsseldorf, Germany this April,
including a new line for high-potency compounds.
An investigation in the aftermath of a fire and explosion at one of
Cambrex' US plants last year has found the firm in breach of
several safety regulations and the company will be fined
accordingly.
Aceto, the US-based distributor and marketer of fine and industrial
chemicals, is making a determined pitch for the pharmaceutical
intermediates sector in Japan.
Another sharp decline in biomedical production saw overall
manufacturing output in Singapore fall for the second month running
in December, prompting fears that the heavily trade-reliant economy
could buckle under a looming US recession.
