Large clinical trials can be particularly useful in the early treatment and prevention of neurodegenerative diseases because of the amount of data collected, though patient recruitment and retention are challenging, says biostatistician.
Eli Lilly and Company and AC Immune have signed an agreement for the research and development of tau aggregation inhibitor small molecules, and AC Immune signed a strategic partnership with WuXi biologics.
Previous setbacks in Alzheimer’s disease research for disease-modifying treatments have set the stage for a pipeline of new medicines now moving into clinical trials, according to a recent PhRMA report.
US-based researchers have developed a transdermal vaccine for
Alzheimers disease which has been shown to clear brain-damaging
amyloid plaques in preclinical studies, offering hope to millions
of sufferers worldwide.
US drug developer Samaritan Pharmaceuticals has filed a patent for
a new drug that could treat a wide range of neurodegenerative
disorders, including Alzheimer's disease, by clearing out amyloid
plaques in the brain.
Scientists have uncovered a naturally occurring enzyme that can
break down a component of the brain plaques that play a central
role in Alzheimer's disease, which could provide researchers with a
basis for new therapies to treat...
Researchers believe that they have identified a drug target
molecule that could be used to treat mental impairment in people
with Down's syndrome paving the way for a treatment that could
improve the quality of life for sufferers.
A Phase I clinical trial, which is investigating the
pharmacological activities of a compound for the treatment of
Alzheimer's disease, has just been completed with results
indicating improved efficacy and pharmacokinetics over...
A handful of Alzheimer’s drug treatments and lifestyle-based
interventions shared the spotlight at the first ever Alzheimer’s
Association Prevention conference, in which scientists worldwide
took the opportunity to showcase the latest...
A new therapeutic technique based on a small molecule working in
tandem with a larger protein has been shown to block accumulation
of the brain-clogging amyloid protein seen in Alzheimer's disease,
raising the possibility of...
Researchers have identified a protein that protects the brain from
the destructive effects of Alzheimer's disease, protecting brain
cells by blocking another toxic protein that contributes to the
A study, which uses immunoglobulins to treat multiple sclerosis,
may also be able to help patients with Alzheimer's. The discovery
seems to point towards an approach, which treats Alzheimer's with
anti-bodies, which are...
The first clinical trial of a peptide that mimics the cellular
adhesion molecule NCAM is due to take place in the UK in the third
quarter of this year, bringing a potential new treatment for
Alzheimer's disease a step closer,...