Vitamin B3 may be used to improve the efficacy of antibiotics when treating drug-resistant ‘superbug’ infections such as MRSA, according to new research.
The US Food and Drug Administration backs pyrogen and endotoxin testing recommendations developed by the USP and AAMI, but has issued a Q&A to set out the regulatory perspective
3M, the US-headquartered multinational, has launched a new range of bio filters which it says raise the benchmarks for flow-rate, organism reduction and efficiency across a range of applications.
RecipharmCobra Biologics has received an EU patent for a genetic modification tech that allows antibiotic resistance genes to be removed after insertion is complete.
Millipore has expanded its microbial detection offering with Milliflex Quantum which, it says, enables manufacturers to respond to contamination issues earlier in the drug and vaccine production process.
Glycos Biotechnologies has produced lactic acid in a pilot plant using its sustainable technique, successfully scaling up from a laboratory setting to provide an alternate source for the chiral synthon.
Detection of Mycoplasma contamination in biologics manufacture can be cut from up to 35 days to four hours using Millipore’s MilliPROBE, according to the company.
PX'Therapeutics SA, formerly called Protein'eXpert, has set up an additional biomanufacturing unit dedicated to producing therapeutic proteins and monoclonal antibodies in mammalian cells.
India-based CRO Vimta Labs is aiming to lower the cost of diagnostic services by developing new panels using MassTag PCR technology licensed from Columbia University, New York.
Swiss life sciences solutions firm Lonza has been contracted by US biotechnology group Elusys Therapeutics to produce Anthim, its late stage Ab candidate treatment for anthrax infection.
MRSA could be treated through a combination of an antimicrobial drug, a peptide and light, according to researchers who have hailed the treatment as a “magic bullet”.
US researchers have for the first time synthesised an important class of drug compounds - the aromatic polyketides - in Escherichia coli, a bacteria widely used in microbial production.
The MicroSEQ detection platform, developed by Applied Biosystems, looks set to revolutionise the detection of bacterial Mycoplasma in industrial scale biopharmaceutical manufacturing.
BioVigilant says that two type V DMFs for its IMD-A rapid microbial detection system, which it has filed with the US FDA, can now be referenced by clients hoping to use it in drug manufacture, potentially reducing review times.
Novozymes Biopolymer’s novel hyaluronic acid (HA) HyaCare has been named winner of this year’s gold innovation award at the CPhI worldwide conference in Frankfurt, Germany.
UK and Swedish researchers have developed a system that eliminates the need for antibiotics and resistance genes in the engineering of biopharmaceutical products, making the process both safer and less costly.
A new Master Cell Bank (MCB) capable of producing pure cell culture
for the manufacture of the anti-biofilm enzyme DispersinB
represents a significant breakthrough, according to developer Kane
Biotech.
With manufacturing productivity in the pharmaceutical sector widely
acknowledged as being in need of modernisation, a US firm believes
it has developed a technology that could carve days off the time
spent on microbial testing, a...
A new, freely available database has been launched that provides
comprehensive information about the 600 known bacteria living in
the human mouth. Many of these bacteria also cause infections
in the lungs, blood and skin, so the...
Scientists have provoked a soil-dwelling bacteria into producing a
potent antibiotic by pitting it against another bacteria, despite
the fact that previously it had never been known to produce such
products.
A new 'map' that depicts the interactions between proteins from
pathogens and humans could help explain how viruses and bacteria
manage to trick victim cells into carrying out their dirty work.
Cellexus Biosystems, the UK company that designs, manufactures and
sells disposable cell growth technology for the biopharmaceutical
industry, is extending the rental plan offered on its CellMaker
Lite2 single-use bioreactor in response...
The technology used to decipher an organism's gene sequence has
come on in leaps and bounds this year. So much so that the US
National Institutes of Health (NIH) has now released funds to
create new tools to analyse this wealth...
The quest for more efficient methods of generating biofuels has
been boosted by a metagenomic study of the gut bacteria that enable
termites to digest wood.
New research has shown that even if laboratory rats are genetically
identical they can still develop distinct metabolic profiles that
could skew drug toxicity and metabolism studies.
Industrial microbiology expert bioMerieux has acquired Australian
firm BTF, strengthening its quality control (QC) and manufacturing
quality assurance (QA) offerings to the pharmaceutical industry.
US researchers have shown certain organic solvents can be used to
selectively extract therapeutic proteins from host bacteria,
avoiding the need for cell lysis and increasing product purity by a
factor of five.
Swiss researchers have developed a method that combines bacterial
capture, lysis and the purification of plasmid DNA to improve
industrial-scale bioprocesses.
The latest in a series of periodic roundups of drugs that have
moved from preclinical research into clinical testing via the
announcement of a Phase I trial or an application for a trial to
industry regulators.
Denmark's Novozymes has set up a dedicated business unit in the UK
to make and sell ingredients that support companies wanting to
produce biopharmaceuticals without using animal-derived
constituents.
The approval of GlaxoSmithKline's (GSK) Altabax gives clinicians
the first new class of topical antibacterial treatments in nearly
20 years - adding more firepower to the fight against bacterial
resistance.
Scientists have used a biochemical chip to explain the important
role a certain protein plays in the mating habits of yeast cells.
The finding could lead to new cancer drugs with fewer side effects.
Microbiology specialists Oxoid have added a new growth medium
product to their catalogue of microbiological culture media, for
use in aseptic process simulations.
Scientists have today unveiled a technique for tipping the balance
in favour of antibiotics in their fight against increasingly
drug-resistant 'superbugs'.
Researchers at the University of Leeds have genetically modified a
common gut bacterium to respond to a sugar and produce a treatment
for Inflammatory Bowel Disease (IBD).
Cellexus has introduced a technology - CellMaker Lite - that
satisfies the appetite for disposable bioreactors, grows bacterial
and mammalian cells efficiently and cuts production costs.
Integra Biosciences is hailing its novel cell culture system as
being responsible for dramatically transforming the effectiveness
of small-scale antibody production.
Oxoid has introduced a new plate design for the Oxoid range of
Contact Plates, which aims to make the microbiological testing of
surfaces even easier to store, handle and use.
