At the Conference on Pharmaceutical Ingredients (CPhI) opened its
doors yesterday, In-PharmaTechnologist.com spoke with Nick Hyde,
global business director at leading contract manufacturer
Dowpharma, to hear his views on the state...
A new anti-infectives company, spun out of the Sanofi-Aventis
group, has received €40 million in financing from an international
group of leading life science investors led by Atlas Venture and
including Sofinnova, 3i, Abingworth...
A technique used to conduct fully automated high throughput
mutation detection in microbial genomes, has shown greater
sensitivity over existing methods. The method analyses genetic
modification in bacteria and other disease causing...
A one-dose, microsphere formulation of azithromycin is as effective
as several days' treatment with other drugs for respiratory tract
infections (RTIs), according to new clinical data.
Cambrex has made a second deal to increase its presence in the
microbiological testing, this time acquiring France's Genolife for
approximately $6 million (€4.75m) in cash.
A Cambrex subsidiary has formed an alliance with Epoch Biosciences
to apply a technology usually applied in genomic analysis to
microbiological quality control for manufacturing processes.
Sulfa drugs, the primary therapy for treating anthrax, are losing
the battle in its effectiveness in treating this bacterium, of
which antibiotic-resistant strains are emerging. Now,
computer-generated images which show bacterium...
A new generation of 'smart antibiotics', which uses a virus that
adapts to recognize and attack bacteria, could become the latest
approach to tackling the growing public health problem of
antibiotic-resistant pathogens such...
Proliant Biologicals has launched a new cell culture medium that
can be used for the production of monoclonal antibodies and other
proteins but is claimed to be more economical than a rival product.
Separation and filtration specialist Millipore has launched an
automated system for the rapid detection, response and resolution
of microbial contamination in manufacturing processes.
A US biophysicist has won an award for developing a new process
that simplifies the production of proteins in the widely used T7
gene expression system.
A novel approach to treating tuberculosis (TB), focusing on a
potential drug target in the cell walls of Mycobacterium
tuberculosis, the bacterium that causes TB, a disease that is
reappearing as new, multiresistant drug-strains.
This week has seen three companies put forward different solutions
to the topical issue of improving the yield of proteins and nucleic
acids made by biomanufacturing technologies.
Researchers in the US are testing a new way to treat HIV by
destroying the virus as it enters host cells. The treatment is
based on the genetic manipulation of the immune cells that HIV
infects to enable them to destroy the virus.
A new range of polyurethane resin-based floor systems that combines
an antimicrobial layer has been launched. Manufacturer John Lord
claims that this new innovation can help manufacturers reduce the
level of bacterial contamination...
Scientists in the US have developed a new software package that can
predict the activity of enzymes, potentially improving the design
of new drugs and industrial reagents.
A collaboration between Switzerland's Genedata and Bayer of Germany
has led to new way of developing assays for antibacterial activity
and accelerate the search for novel antibiotic classes.
Since they were first described in 1998, the existence of so-called
nanobacteria - tiny RNA-based organisms that form microscopic
mineral structures that have been blamed for causing calcified
deposits in diseases such as atherosclerosis...
Researchers at Merck Research Laboratories have discovered a
small-molecule drug that blocks the activity of FtsZ, an emerging
therapeutic target for antibacterial agents.
The first in a new class of antibiotics has been approved in the
USA for the treatment of complicated skin and soft structure
infections, including those caused by methicillin-resistant
Staphylococcus aureus (MRSA).
Danish biotech company Fluxome Sciences , based at the Technical
University of Denmark, has entered a cooperation agreement with the
US biotech company Bio-Technical Resources concerning development
of optimised fermentation processes,...
US company Biolog this week received a patent for its Phenotype
MicroArray technology. The patent, number US 6,472,201, is granted
for comparative phenotypic analysis of two or more microorganisms
using a number of substrates within...