Around half the products made at the Broomfield facility will be discontinued or divested says Novartis, blaming increased US generics competition and customer consolidation for the closure.
With several systems and process improvement initiatives underway, the growing contract research organization (CRO), Venn Life Sciences, continues to look for earnings enhancing opportunities, says CEO.
A restructuring programme which closed two US facilities and slashed hundreds of jobs has paid off says Amgen, attributing increased margins to better manufacturing efficiencies.
According a recent survey, while there is a disconnect between Sponsors and Providers in some areas, the industry as a whole agrees that there is room for improvement.
According to a recent survey, there are significant advantages to adopting eTMF – although some challenges still remain in the shift towards paperless clinical trials.
Covance has reported capacity use at its preclinical toxicology business is in the 70% range, meaning it is still well below optimal levels despite recent improvements.
As pharma manufacturers look to cut costs and increase quality, over 70% of industry executives interviewed for a recent CPhI report say they are actively investing in manufacturing techniques and technologies to achieve these goals.
Demand for early phase services have increased but the industry is still “far away from the boom times of the early to mid 2000s,” according to an ISI analyst.
Linking peptide and small molecule drugs to albumin will improve pharmacokinetics, says Almac as it partners its manufacturing capabilities with Novozymes’ half-life extension platform.
New research suggests that – in general - strategic partnerships are working but CROs still need to improve on sponsors’ ‘high priority’ objectives or risk losing deals.
ClearTrial has launched an upgrade to its clinical trial operations (CTO) software, adding more country specific knowledge, such as labour rates, to help companies forecast costs and timelines.
OmniComm has launched a comprehensive Phase I eClinical tool, which it believes is the first of its kind, to help users make cost and time savings by improving efficiencies.
In the economic downturn biotechs have cut back on outsourcing to Asia and opted to use the US instead because they lack the resources to manage overseas relationships, according to a SOCMA representative.
Parexel has entered into an alliance with Mortara Instrument to bolster its early phase cardiac safety capabilities and improve the assesment of new compounds.
ATMI has launched a powder transfer bag, for substances such as APIs and excipients, which it claims has three times the shelf life of alternatives, increases process efficiency and improves safety.
Xceleron will provide services to GSK and its collaborators, such as academics and biotechs, under a novel deal that emphasises the big pharma’s attempts to change its drug development model.
Demand for biopharmaceutical contract manufacturing will grow 16 per cent a year over the next five years, according to analysis by US market research group HighTech Business Decisions.
A new 9,500 unit per hour sterilised syringe filler was a highlight of Bosch Packaging Technology’s busy programme of machine launches at Achema 2009 in Frankfurt, Germany this week.
German fine chemicals company Saltigo is benefiting from a cash
injection from its parent company, Lanxess. The German firm is
earmarking €30m for plant modernisation at its subsidiary, and a
€10m brand new multi-purpose facility...
Rexam has introduced two new desiccant caps - Evipharm &
Secupharm - that use a filled in-line silica gel as a desiccant to
improve shelf life of the drug.
Biopharma and lifesciences firms should make use of e-learning
software solutions to relieve the burden on keeping staff updated
on regulatory and compliance training.
Rhodia was present at this year's CPhI, alerting the industry to
its latest product updates, spawned out of the market demand to
provide products that allow its customers to better address process
and handling requirements.
Varian introduces two new micro extraction solid phase extraction
(SPE) formats for bioanalytical research that aims to deliver
improved performance and a more streamlined sample preparation
process enabling vacuum-free SPE processing...
A collaboration agreement to identify and develop an improved
variant of CT500, a non-antibody protein with antagonist activity
against HMGB1 has been established, paving the way for
applications, to treat tumours and autoimmune diseases.
UK chemicals group Croda said strong demand for its marine and
plant-derived oils in the personal care and healthcare sectors
lifted sales and helped improve first half operating profits.
The US Food and Drug Administration is to develop a blueprint for
speeding up the approval of new medical products to counteract the
slowdown in R&D productivity in the pharmaceutical industry,
writes Phil Taylor.
Swiss-American laboratory instrument company Mettler-Toledo saw its
fourth-quarter revenues climb 7 per cent to $370 million (€290m)
although the weak dollar accounted for a large proportion of the
increase.
US packaging giant MeadWestvaco has started the second phase of a
restructuring programme aimed at improving productivity at the firm
and boosting both earnings and cash flow, at the cost of 1,000 job
cuts and a number of facility...
Pall has reported a 10 per cent rise in sales to $471 million
(€430m) in the fourth quarter, boosted by currencies and the
recently-acquired FSG operations.
Ultrasound monitoring of process column chromatography can lead to
significant improvements in productivity, lower costs and greater
drug purity, says study
