Onconova to use Mission Bio’s Tapestri targeted single-cell DNA analysis platform to advance its cancer therapy, rigosertib, into Phase III clinical trials.
A natural substance found in stinging nettles and ants repeatedly attacks cancer within cells, say scientists developing low-dose alternatives to current chemotherapy drugs.
A new study published in the Institute of Physics Science reveals that Chinese researchers have developed gold nanoparticles that may help deliver cancer treatments to specifically targeted cells.
A tool that more quickly identifies proteins present in cancer
cells and identifies targets for immunological therapies and
diagnostics has been reported by Austrian researchers.
Japanese researchers have used an advanced microspectroscopy
technique to study the cell cycle of yeast without the need for
fluorescent imaging agents that can potentially alter the cellular
environment.
As the AACR-NCI-EORTC cancer conference comes to an end today in
San Francisco, DrugResearcher.com takes a look at some of the most
innovative drugs on show.
Abraxis Bioscience has bought the worldwide rights to a discovery
platform designed to generate new therapeutics and identify new
drug targets that alter the p53 tumour suppressor signalling
pathway.
US researchers have developed a three part screening process to
find new cancer genes and used it to identify a new gene associated
with about a third of all breast cancers.
A workshop being held this week in Italy has shed new light on how
cancer cells spread around the body, highlighting new strategies
for potentially combating the disease.
A new imaging approach tested out by US researchers has resulted in
the discovery of small molecule compounds that are able to perform
the functions of a gene commonly mutated in many types of cancer.
A potential therapy, which specifically targets cancer cells, could
be in the offering after Neotropix received FDA approval to begin
clinical trials of a drug candidate that offers new drug treatment
hope for advanced cancers.
Pharmaceutical company, Phosphagenics, has announced the
commencement of animal studies on its anti-cancer compound, which
claims to destroy diseased cells while not affecting normal ones by
primarily acting as a signalling molecule...
The question as to why some cancers resist drugs could be answered
by the discovery of new mechanisms, which delve deeper into how
cancer cells evolve to become resistant to various chemotherapy
drugs.
US scientists have claimed to have developed the next generation of
effective viral-based therapies for cancer in which 'terminator'
viruses are deployed to destroy primary tumours.
The possibilities nanotechnology has in drug and therapeutic
applications was demonstrated once again after researchers were
able to demonstrate the destruction of cancer cells whilst keeping
healthy tissue unharmed.
Scientists have created the nanotechnology equivalent of a Trojan
horse to smuggle a powerful chemotherapeutic drug inside tumour
cells - increasing the drug's cancer-killing activity and reducing
its toxic side effects.
Cytopia has received the green light to trial a promising new drug
that could prove effective in the fight against advanced solid
tumours. In animal studies, the drug candidate has already shown
efficacy in killing cancer cells in...
US researchers have developed a new approach to fighting cancer,
which uses nanoscale particles that can detect and destroy
cancerous cells. This ability differentiates it from current
molecular imaging approaches, which only detect...
With the absence of any truly effective drug treatment for brain
tumours, news of researchers working on innovative treatments for
one of the deadliest tumour types raises the possibility of
readdressing the current situation and...
Researchers have found a protein, which plays a significant role in
colorectal carcinoma. The protein blocks the ability of tumours to
activate a natural self-destruct mechanism that would clear the
cancer from the body.
Cyclacel researchers and collaborators have solved the 3-D atomic
structure of human Proliferating Cell Nuclear Antigen (PCNA), a
protein involved in cancer. The discovery should prove crucial in
designing and developing drugs that...
The first grants given in the UK for drug development in early
phase clinical experiments have been awarded to gene therapy trials
that may herald a breakthrough in intra-abdominal cancer which has
an average survival rate of less...
The discovery relates to the activity of telomeres - thimble-like caps that are added to the ends of chromosomes in order to protect DNA from damage....
Researchers in the UK have devised a means of using bacteria as a
means of delivering proteins into tumour cells and killing them,
raising the hope that this could form the basis of a new treatment
for cancer.
Researchers in the USA have uncovered a cellular mechanism that
could lead to a larger role for retinoids, compounds derived from
vitamin A, in the treatment of cancer.
