The development of a highly sensitive assay for the detection of
drug-resistant HIV strains could aid our understanding of how the
virus mutates, helping new drug discovery programs.
Thanks to a small boy who couldn't feel pain, scientists have
discovered a gene mutation that opens the door to developing
powerful new drugs that could elimate all pain.
Fluidigm has launched its digital PCR technology, allowing
scientists to analyse a single DNA template, which will give them
the opportunity to detect cancer much earlier.
The once hyped antisense sector of the pharmaceutical industry has
again proved a disappointment after one drug in development was
refused approval and another was scrapped.
The dream of personalised medicine has taken another step towards
reality as scientists have developed an innovative nanomechanical
sensor for detecting disease and observing the body's reaction to
treatment.
Researchers in Denmark have discovered a new drug delivery method
based on sugar nanocapsules that could be a breakthrough to treat
cancer, viral diseases and hereditary disorders.
Applied Biosystems introduces a new software tool that aims to
simplify DNA methylation research aiding researchers to further
their understanding of this process in the genetic basis of complex
diseases, such as cancer.
The National Cancer Institute (NCI) has revealed the grant
recipients for its Cancer Genome Atlas pilot project, which will
see three institutions using microarray platforms from Agilent
Technologies.
Scientists have come up with a DNA-based computer, which could lead
to faster, more accurate tests for diagnosing West Nile Virus and
bird flu more quicker and more accurately.
Researchers have demonstrated that a new compound has the potential
to effectively cure epilepsy, raising hopes that a new drug can be
produced to treat epileptic patients, who currently have no access
to treatment.
As it looks to the "future of pharmaceuticals," Sandoz is planning
a "powerful biopharmaceuticals programme" with the construction of
a new biopharmaceuticals development centre in Ljubljana, Slovenia.
Researchers believe that a little-known antibiotic could well prove
effective against cancer, showing promise because it has not shown
toxic side effects, which continue to blight current anti-cancer
agents.
Mirus Bio has made available a new RNAi tool that analyses gene
function in vivo that allows scientists to study the biological and
physiological impact of a change in gene expression, which is
useful in the identification of new...
Biotechnology firm Codexis says it has reached an important
development milestone in its effort to design a biocatalytic
process to produce a key intermediate for a Schering-Plough drug,
reducing manufacturing costs and environmental...
Researchers have developed a new technique that they claim will
vastly speed up the search for new cancer drugs and antibiotics
that has proved problematic and time expensive in the drug's
development cycle.
Seattle drug firm ZymoGenetics has taken Bristol-Myers Squibb (BMS)
to court for infringement of its fusion protein technology patents
by several products, including arthritis medication Orencia
(abatacept).
Nexcelom Bioscience, a provider of instruments for cell-based
assays, has just launched a new cell counter to make the cell
counting process quicker and easier.
A new service introduced on the back of customer demand has been
launched by Aviva Systems Biology which make available a method for
genome-wide detection of promoters and enhancers that interact with
proteins or carry modifications.
SuperArray Bioscience has made available a range of pathway-focused
real-time PCR gene panels that allow scientists to use their
real-time PCR instrument just like a microarray in the multiple
stages involved in drug discovery and...
Murex Pharmaceuticals has licensed Ariadne's software solution,
which is to play a vital role in the visualisation and analysis of
biological pathways and gene regulation networks for cancer
therapeutics development.
Agilent Technologies has introduced its new microarray that offers
high-resolution genomic coverage, whilst enabling multiple
experiments per slide. The technology has the potential to make
savings both in time and cost.
Applied Biosystems (AB) is to acquire Agencourt Personal Genomics
(APG) for approximately $120m (€94m) in cash in which the life
science specialists will gain a novel, high throughput approach
with applications in DNA sequencing,...
Asterand has announced the formation of a partnership with Rubicon
Genomics to develop new cancer diagnostic tests that identify the
DNA methylation mechanism that causes cells to become cancerous
making the assignment of treatment...
Drug companies have been encouraged by recent studies that suggest
that by blocking the binding of transcription factors may be a way
to short-circuit the harmful effects of diseases.
Invitrogen has formed a collaboration to supply reagents for
Solexa's Genome Analysis System, a sequencing technology that has
the potential to generate over a billion bases of DNA sequence data
per run.
PerkinElmer has launched a new antibody-free kinase assay
technology that is set to play a major role in drug discovery by
allowing researchers to perform direct measurements of kinase
activities on full-length protein substrates...
deltaDOT launches a unique capillary-based DNA sequencer that has
been specifically developed to provide a low-cost rapid throughput
DNA sequencing solution in numerous drug discovery applications.
Vandalia Research has launched a new DNA amplification service that
it claims will speed up the mass production of high-quality DNA
sequences with the polymerase chain reaction (PCR), while at the
same time reducing the risk of contamination.
The laboratory identification of promising candidates for new
anti-cancer drugs is to be made significantly easier after
scientists developed a litmus test that determines the bonding
strength of DNA, small molecules and proteins...
US scientists have uncovered a mechanism of action that explains
how cells respond to DNA damage and other stresses that if
disrupted can cause cancer. The discovery could lead to new
diagnostic markers and cancer treatments with...
US scientists have discovered a way to improve the effectiveness of
antisense cancer drugs that involve using gold nanoparticles, which
when combined with DNA, outperform conventional antisense agents.
A novel lab technique, which involves RNA interference to silence
genes in immune cells, is set to provide biology researchers
broader access to RNA interference, especially for scientists doing
research in immunology.
European researchers have unlocked more secrets of how the HIV and
SARS virus operates, which if exploited could be the starting point
for a host of effective antiviral drugs that combat the virus'
mechanism of action.
Fresh from its recent acquisition, Applied Biosystems (AB) made an
appearance at the recent Analytica show in which the company
demonstrated the capabilities of its products for life science
research in the laboratory.
A large-scale process, which focuses on highly purified and high
viral titer vectors, may facilitate the fast track development of
Adenovirus and AAV-based recombinant DNA vaccines for diseases such
as the Avian Flu.
Researchers at Michigan State University have found that
second-generation taxols, which currently rely on assembly by
semisynthetic organic chemistry approaches, can be produced in a
cheap and environmentally friendly fashion using...
Bertin Technologies makes available its solution for biological
sample preparation to extract nucleic acids (DNA & RNA), and
proteins - a crucial process in drug discovery and development as
well as having implications in the...
Illumina has introduced two new genotyping BeadChips that offers
the highest data quality of any genotyping array currently
available, with call rates that routinely exceed 99 per cent,
reproducibility and accuracy approaching 100...
Scientists have made available a powerful new tool for studying
brain development, which will help scientists discover the genetic
origins of brain cancers, which could speed development of novel
drugs to treat them.
Affymetrix introduces its new ChIP-On-Chip array product line that
its designers hope will provide drug researchers with new
whole-genome tools to assist scientists discover DNA-Protein
interactions.