Dutch chemicals giant DSM and France’s LibraGen are targeting the chemical and pharmaceutical industries with their new chiral amine production accord, which aims to develop a range of new catalytic enzymes.
A key study performed by US scientists has uncovered detailed
structural changes, which a catalytic enzyme undergoes in order to
carry out its biological function. The findings challenge
traditional hypothesis and may aid in future...
Biotechnology firm Codexis says it has reached an important
development milestone in its effort to design a biocatalytic
process to produce a key intermediate for a Schering-Plough drug,
reducing manufacturing costs and environmental...
Researchers in the US have developed an exciting new tool that
enables scientists to watch cell chemical activity in real-time.
The tool's development has major implications for speeding up new
An enzyme-based process operated by Lonza for the production of the
major chiral building block for Pfizer's Lipitor, the world's best
selling drug, has won its designer Codexis a top green chemistry
award for its high yield,...
PerkinElmer has launched a new antibody-free kinase assay
technology that is set to play a major role in drug discovery by
allowing researchers to perform direct measurements of kinase
activities on full-length protein substrates...
Molecular Devices has launched its proprietary system, which offers
Fluorescence Polarisation (FP) and Time Resolved Fluorescence
Resonance Energy Transfer (TR-FRET) detection, allowing researchers
to select between these two well-known...
Researchers have come up with definitive proof that proteins can be
custom-designed for a new and pre-determined activity, signalling a
new direction in drug production as well as having relevance to the
biotechnological and medicinal...
US researchers have identified an enzyme activity that is
inactivated in all reported mutant forms of a disease protein,
opening up opportunities for therapies to treat ataxia, a rare
hereditary neurological disease that affects 1/100,000...
US company Biotrove says its mass spectrometry-based
high-throughput screening (HTS) system, RapidFire Lead Discovery,
has been used to screen more than a million individual samples over
the last 12 months.
Researchers have developed a new structural understanding of how
the two key subunits of kinases, one of the most important classes
of enzymes, work together. kinases have increasingly become prime
targets for drugs to treat an array...
Tool supplier, EMD Biosciences has released the first comprehensive
guide to inhibitors for signal transduction and drug discovery
research that will enable researchers to pinpoint specific enzymes
as a possible target for drug therapy.
Sulfa drugs, the primary therapy for treating anthrax, are losing
the battle in its effectiveness in treating this bacterium, of
which antibiotic-resistant strains are emerging. Now,
computer-generated images which show bacterium...
Switzerland's Lonza Group said yesterday that it will use a novel
process developed by US-based biocatalysis company Codexis for the
synthesis of a key chiral pharmaceutical compound used in one of
the world's major human...
Diversa has entered into a deal aimed at boosting its manufacturing
capacity in enzymes used for industrial processes, including the
production of pharmaceuticals. The agreement with Mexico's Fermic
is designed to step up the...