Terapio has secured $5m (€3.3m) in funding to develop RLIP76, which is being used to counteract radiation and deliver large molecules across cell membranes, such as genetic material across the BBB.
Clinical Data is to sell Cogenics division, which provides services including sequencing and gene expression, to Beckman Coulter’s Agencourt Biosciences' business for $17m.
Gene therapy could be advanced by a worm more commonly associated with causing a deadly parasitic disease, according to researchers presenting at the British Pharmaceutical Conference (BPC).
Febit has updated its Geniom microRNA analysis platform with the
latest version of the Sanger Institute's database of all known
miRNA elements. The upgrade should provide scientists with a more
detailed microRNA profile of their...
Scientists have successfully created the first artificial
transposon - a piece of DNA which randomly "jump" around the
genome, cutting and pasting itself throughout the strands of DNA.
Bayer Healthcare is to deploy a new technique, developed by
Millipore, for genetically engineering cells to produce
pharmaceutically useful proteins that could both increase the yield
and accelerate drug production.
Integrated DNA Technologies (IDT) has launched LabLinker, a free
online system for sharing genome sequence data and even share
shipping costs of orders.
Researchers can now reduce the cost and time taken to breed goats
that can produce therapeutic proteins using gene therapy.
Experts say these transgenic animals could cut the cost of insulin
and other cancer-fighting proteins.
WaferGen has launched a new subsidiary in Kedah, Malaysia, with the
express purpose of overseeing research and development of its
real-time PCR system.
Skin cancer detection specialists DermTech have decided to turn
their hand to acne after signing an agreement with Stiefel
Laboratories to identify spot-causing genes.
Medgenics' Biopump could be the solution to the issues surrounding
protein therapy and is set to take on the $51bn US
biopharmaceutical market after raising £3.28m ($6.76m) in funding
in its Initial Public Offering.
Loneliness has been linked to serious diseases such as cancer,
heart disease and infection but a new study could point to new ways
of reducing its impact on health.
Sigma-Aldrich has launched a new technology that promises to
dramatically simplify and speed-up high-throughput (HT) RNAi
screening of the human kinome.
PerkinElmer has launched an 'introductory configuration' of its
Opera system to lower the upfront cost of adding high content
screening (HCS) to drug discovery and systems biology programmes.
Australian biotech company, Benitec, is about to start dosing
patients in the first ever human trial of its RNA therapy, which
attacks HIV on three separate fronts.
Applied Biosystems (ABI) has launched its TaqMan microRNA (miRNA)
assays in array format to help researchers search for miRNA
biomarkers more efficiently from smaller samples.
The European Commission (EC) has given a €2.75m grant to a
consortium of companies, led by Amaxa, to develop the first ultra
high-throughput (UHT) devices for transfecting cells.
PerkinElmer has introduced two multiplexing platforms for genomic
research, which provides important tools for improving gene
expression validation, molecular karyotyping and genome profiling.
BioDiscovery has released a new array module for its Imagene
software that provides an advanced array-based DNA copy number
analysis and visualisation tool for the drug discovery sector.
Mobious Genomics has announced a prototype version of a new
immunoassay that identified a low concentration bacterial sample
within 40 seconds, vastly improving on the six - forty eight hours
it currently takes to identify the same...
Researchers think they have found an explanation as to why
"flesh-eating" bacteria are so resistant to antibiotic treatment,
which could contribute to new strategies for treating necrotizing
fasciitis, halting its rapid...
Mirus Bio has made available a new RNAi tool that analyses gene
function in vivo that allows scientists to study the biological and
physiological impact of a change in gene expression, which is
useful in the identification of new...
Researchers believe that a genetic discovery involving a cellular
signal that aggravates the symptoms of MS may be a viable target in
new therapeutic approaches, which could alleviate the burden of
this debilitating neurological disease.
Researchers have identified a gene that plays a pivotal role in
initiating two DNA damage detection and repair pathways in the
human genome, suggesting that it functions as a tumour suppressor.
Researchers have taken a special interest in mechanisms they have
identified as an explanation for the causes of Parkinson's disease,
which they say, may facilitate research aimed at finding novel
medical treatments and other...
Applied Biosystems (AB) make available a wider range of microRNA
assays, expanding the selection to 300 individual assays that are
ideal for cell differentiation, developmental biology, stem cell
and cancer research.
European researchers have unlocked more secrets of how the HIV and
SARS virus operates, which if exploited could be the starting point
for a host of effective antiviral drugs that combat the virus'
mechanism of action.
Agilent has upgraded its GeneSpring GX 7.3 gene expression
informatics software, giving it new features designed to allow
researchers to understand faster what their results really mean.
British gene therapy firm Oxford Biomedica has licensed its VSV-G
viral envelope technology for gene delivery to American biotech
company VIRxSYS which hopes it can use it to successfully produce
its promising anti-HIV/AIDS product...
A new laboratory method for distinguishing pathogens from harmless
relatives has been developed by scientists in the US. The
high-throughput technique will enable the quick identification of
pathogens, which could be used for bioterror...
Honeywell launches a new formulation of BMI activator, which is
used to synthesise DNA and RNA oligonucleotides for therapeutic and
medical diagnostic applications. The formulation aims to result in
higher yields and lower overall...
Sigma-Aldrich has strengthened its position in the RNAi and
cell-based assay market by signing a series of agreements in which
the life science company has acquired a minority equity stake in
Genospectra and is granted access to various...
Scientists have taken a major step forward in the diagnosis and
treatment of HIV as it was revealed that the virus' 3D structure
had been constructed. This achievement will prove instrumental in
the development of more effective...
With two acquisitions in two months, US biotechnology major Genzyme
has strengthened and diversified its ability to develop gene
therapy products that use either adenovirus or adeno-associated
virus vectors.
Tripos has announced the latest details in its cost cutting
strategy, which is expected to result in job losses, principally in
the UK. The cuts come as Tripo's four-year $90 million file
enrichment project with Pfizer draws...
Invitrogen has created three new business divisions in a move to
strengthen its position in the growing biotechnology industry and
drive growth through improving links between its product
development cycle and customer base.
Sigma-Aldrich Fine Chemicals (SAFC) Biosciences chose the CPhI Expo
in Madrid to announce a series of updates concerning company
activity. The custom manufacturing group is currently undergoing
construction of a new US facility aimed...
Scientists have demonstrated that a mouse virus that causes mammary
cancer can infect human cells. This latest study attempts to shed
light on a debate stretching back to the early 70's, which show
that a viral-like agent may...
A new technique that adds to the effectiveness of gene therapy has
made a breakthrough after it was revealed that the method had cured
phenylketonuria (PKU) in mice.
Life sciences is to be given priority under a European Commission
(EU) framework, which focuses on creating a knowledge-based economy
to ensure increased funding for this industry.
Ambion and Rosetta Genomics have announced a licensing and
commercialisaton agreement to advance microRNA research. The
results will facilitate microRNA research that hails this as a
promising area in the treatment of a range of diseases.
A new study, which uses a new method in identifying the specific
gene involved in high cholesterol has been hailed as, "a landmark
publication." The study also describes the potential to use this
approach in forming a treatment...
New techniques aimed at directly controlling the expression of
genes by activating or inactivating them at the DNA level could
lead to drugs for the treatment or cure of almost any disease, say
researchers
Targeted Genetics has announced the issuance of an
Additional-Associated Virus (AAV) vector technology patent, which
describes a technology that may help to maximise gene expression
efficiency with little or no loss in viral payload.