Targeted Genetics has announced the issuance of an
Additional-Associated Virus (AAV) vector technology patent, which
describes a technology that may help to maximise gene expression
efficiency with little or no loss in viral payload.
An improved new statistical method developed by genome researchers,
is set to streamline the computation required to identify the
potential locations in the genome, as well as linking more gene
expression traits to two loci.
Sigma-Aldrich has launched a handful of laboratory equipment and
technological developments that could prove useful in drug
discovery. The life science company is currently in the midst of a
reorganisation of its operating structure...
German biotechnology company ICON Genetics is to start field trials
of a transgenic tobacco crop that will be used to produce an enzyme
with potential as an active pharmaceutical ingredient and as a
catalyst for the manufacture of...
US scientists have shown that microRNA (miRNA) plays an essential
role in the development of the fruit fly. The discovery means that
miRNA could emerge as a new target for interventions aimed at
treating disease, or as a therapeutic...
Lexicon Genetics and Xoma have announced the formation of a
collaboration to jointly develop and commercialise antibody drugs
that could be effective in treating diet-induced obesity and
enhanced insulin sensitivity.
UK company ML Laboratories has won a new customer for its gene
expression technology - UCOE - used to improve the production of
proteins for drug discovery and use as therapeutics.
US scientists researching cancer have stumbled across a new
technique that could help them to distinguish between cancer types.
The discovery is set to change the landscape of cancer genetics by
providing laboratories with a procedure...
Researchers have discovered that a certain virus appears to cloak
itself with a recently discovered gene-silencing device to evade
detection and destruction by immune cells. The study is the first
to show how a virus uses the gene...
Agilent Technologies has announced plans to introduce its DNA
microarray-based genomics technology to India, reaffirming its
plans to expand its presence in medical research, drug discovery,
agro-biotech.The Indian microarray market...
Scientists at US biotechnology firm Cell Genesys have developed a
gene expression technology that could improve the commercial
production of monoclonal antibodies and other complex therapeutic
proteins, reports Phil Taylor.
Dharmacon has announced the launch of the first ever product line
that uses reverse transfection technology to screen RNAi libraries
rapidly and cost effectively, increasing accessibility of RNAi
screening to researchers worldwide.
Bio-Rad Laboratories offer to buy BioSource International for
approximately $82 million (€64m) has been rejected again after
BioSource directors concluded that the proposed price was
significantly below BioSource's inherent value.
A new £6 million (€9m) biocentre is set to revolutionise the way
future medicines are produced making them safer and more effective.
The centre, based in the UK, will not only help pharmaceutical
companies to develop better drugs,...
Biomedical engineers and chemists have collaborated on a novel
method that predicts how drugs work in cells. The tool will allow
drug developers to design compounds that will act on a desired gene
and protein targets, eliciting therapeutic...
Sigma-Aldrich has completed the acquisition of JRH Biosciences
division (JRH) for $370 million (€282 million) in cash, extending
its presence in the cell culture product sector and consolidating
its position in the burgeoning functional...
Hamilton Life Science Robotics has taken Invitrogen's Gateway
Technology one step further by creating an automated cloning system
that monitors and tracks each plate undergoing various processes.
The system aims to further refine...
A hive of activity at Agilent Technologies has trnsformed the
company into a significant player in the competitive microarray
platform market with the expansion of its array-based genomics,
disease research and drug R&D applications.
NextGen Sciences has licensed a new technology for protein
expression from Oxford Brookes University that reduces expression
timelines for proteins in insect cells by up to 10 days.
Inpharmatica has announced a discovery collaboration with Novartis
Institutes for Biomedical Research which is to focus on identifying
protein targets for Novartis' drug discovery projects.
Biotechnology company Proteus has been issued with a new US patent
that details the functional screening of candidate active compounds
using in vitro protein expression. The granting of the patent
corresponds to the company's...
Exiqon has launched two new ProbeLibrary expression analysis kits,
covering the genomes of Arabidopsis thaliana and
Drosophila melanogaster, the most widely used models in
disease process and drug target studies.
Scientists in the US have developed Textpresso, a new text-mining
system for scientific literature which implements a unique search
engine using 33 catagories of terms for which a database of
articles and individual sentences can...
Key changes discovered in gene expression that provide an improved
understanding of neurones controlling movement and coordination and
their malfunction and death in Parkinson's Disease has lead to the
possibility of a drug therapy...
German biotechnological company SIRS-Lab, has introduced the
Lab-Arraytor 60-inflammation, a biochip that comprises a total of
780 inflammation-defined genes, specifically to understand the
molecular framework of acute inflammatory...
Biotechnology Company, Nucleonics, has filed a request with the
Commissioner of Patents in Australia for Re-Examination, which
questions the validity of Benitec's patent concerning
gene-silencing technology claiming ambiguity...
UK Life Sciences Company Genetix has launched a new hybrid bed
option designed to compliment its high-throughput, fully featured
QArray microarrayer platform used to detect low-level expression of
genes making it ideal for all microarray...
Dharmacon, supplier of RNA and RNAi research products, has launched
a range of siRNA reagents for its siGenome human siRNA collection,
which supports all phases of research ranging from functional
genomics and initial drug target...
Canada's Chromos Molecular Systems has entered into a collaborative
agreement with Centocor, a wholly-owned subsidiary of Johnson &
Johnson, to develop cell lines for the manufacture of biological
drugs.
A report into the protein biochip industry identifies a major trend
emerging in protein production, either driven by gene approaches or
research purposes for therapeutic drug production. The report cites
growth in the US market to...
A US biophysicist has won an award for developing a new process
that simplifies the production of proteins in the widely used T7
gene expression system.
Researchers in the US have provided the first direct evidence in
mice for the role of an enzyme that specifically controls the
production of serotonin in the brain.
Affymetrix has extended the range of custom microarrays it offers
to customers with the launch of the NimbleExpress Array Programme,
which caters for users that require fewer units.
The European Union has awarded funding worth €2.2 million to the
group of academic institutes behind the 3DGENOME research
programme, which is exploring how the genome functions in health
and disease.
Invitrogen subsidiary Protometrix is gearing up to launch a
microarray containing nearly all the 6,200 or so proteins in the
proteome of the yeast Saccharomyces cerevisiae, a commonly
used organism in genomics research.
Applied Biosystems has launched a mouse genome microarray that can
be used to detect the expression of genes, even when they are
expressed at very low levels.
Growing knowledge about how to manage the risks of gene therapy
could improve the chances of developing successful treatments, said
experts meeting last week to weigh up the progress made on the
technology to date.
An application that will enable direct measurement of nucleic acids
without the need for amplification has been developed by US
Genomics. The application will also allow researchers to perform
validation and characterization of specific...
A consortium of academic and industry researchers, headed by
scientists from French company genOway, has started development of
genetically-modified laboratory rats that can serve as models for
human diseases.
Amersham Biosciences has launched its AKTAxpress system for
high-throughput protein purification, claiming that it can process
samples at four- to eight-times the rate of any other system on the
market, writes Phil Taylor.
US company Incyte Genomics is closing down its Palo Alto-based gene
information division, saying that the availability of free genetic
databases on the Internet has scuppered the unit's business.
Switzerland's Lonza has negotiated exclusive rights to an
expression system, used in the manufacture of therapeutic proteins,
that could be used to shorten the development time for its
customers' biologic products.
UK-headquartered NextGen Sciences has formed an alliance with
Germany's Protagen aimed at developing 'biochips' that can contain
thousands of functional proteins for use in drug discovery.
Affymetrix and liquid-handling specialist Caliper Technologies -
now renamed Caliper Life Sciences - are collaborating on ways of
automating genomics research carried out using microarrays.
Applied Biosystems has launched a new product, based on the
combination of a new set of reagents with a software package, that
promises to speed up genotyping studies carried out on the firm's
3730 and 3730xl analysers, first...
