Intercell hopeful for future of needle-free vaccine
Intercell is seeking new partnerships for its struggling needle-free patch system for delivering vaccines.
AstraZeneca takes its bioinformatics capabilities to Russia
AstraZeneca is will build a center for bioinformatics and predictive medicine in St.Petersburg, Russia by the end of 2011.
Altermune Technologies says it will win back "much needed" resistant pathogens investors
Big pharma companies looking to invest in 'superbug' R&D could soon see a better return through Altermune Technologies' new platform.
Circassia and NanoPass strike up deal over intradermal device
Immunotherapy and vaccine specialist Circassia says its new license agreement with NanoPass Technologies will help its range of allergy products to thrive on the market.
Limpet-derived intermediate supply deal inked by SAFC
Stellar Biotechnologies is supplying SAFC with an intermediate derived from limpets to support production of cancer vaccines.
Round up of CMO deals
Outsourcing-Pharma presents a round up of recent contract manufacturing deals, including business at Lonza, JHP Pharmaceuticals and PCT.
Two projects win backing from CFTI
Two projects have been selected for preclinical testing as part of the Cystic Fibrosis (CF)Technology Initiative (CFTI) in Canada.
PPD and Taijitu form MAb discovery JV
PPD and Taijitu Biologics have launched a new joint venture to help drugmakers develop the next generation of monoclonal antibody (MAb) drugs.
Vical hails universal vaccine adjuvant in research review
Vical has published a review of Vaxfectin data showing the adjuvant boosts the immune response of DNA-based vaccines against cancer and a range of pathogens.
NIAID awards $15.5m to needle-free dengue vaccine
Inviragen and PharmaJet have been awarded a $15.5m (€11.1m) contract by the US NIAID to develop a needle-free dengue vaccine.
EPO reengineered to cross mice BBB for neuroprotection
Reengineering erythropoietin (EPO) as an immunoglobulin G (IgG) fusion protein enables penetration of the blood-brain barrier (BBB) in mice, according to researchers.
Sanofi files sBLA with FDA for intradermal influenza vaccine
Sanofi Pasteur has filed a sBLA with the FDA for an intradermal form of influenza vaccine Fluzone using a microinjection system.
SAFC and Novozymes Biopharma extend partnership in exclusive growth hormone distribution
SAFC and Novozymes Biopharma have agreed to extend their partnership by ten years for the exclusive distribution of LONG R3 growth factor, used for industrial cell culture applications.
TRI wins HIV research support contract with US NIAID
TRI has been awarded a contract with the US NIAID to provide clinical, regulatory and operational support for domestic and overseas HIV research.
Pfenex inks US anthrax vaccine production contract
Pfenex has won a US federal contract to use its expression technology for the rapid, cost-effective production of “unprecedented” amounts of anthrax vaccine.
TRL refocuses new US site on biologic drugs
Tanabe Research Labs (TRL) has revealed details of its new San Diego facility in which the revised layout of the site allows a fresh focus on antibody and biological approaches to autoimmune diseases such as diabetes and rheumatoid arthritis.
PPD increases focus on vaccines and biologics
PPD has added capabilities at the facility acquired from Merck & Co and improved integration of other sites to create its Vaccines & Biologics Center of Excellence, a single provider of multiple laboratory services.
Ranbaxy buys Biovel to strengthen in biologics and vaccines
Ranbaxy Laboratories has strengthened its vaccine and biologics manufacturing capabilities by acquiring India-based Biovel Lifesciences.
InNexus developing topical psoriasis treatment
InNexus Biotechnology believes 2010 is the year for biotechs to differentiate and has begun this process by using its Transmab delivery technology in a product for treating psoriasis.
MedImmune recalls sub-potent FluMist H1N1 vacc in US
MedImmune has recalled unused doses of its intranasal H1N1 vaccine FluMist in the US after checks revealed that some had fallen below the minimum potency threshold in the two months since they were shipped.
GSK and Intercell team on patch that could make H5N1 vacc go further
Intercell’s needle-free patch delivery technology has the potential to change the way vaccines are delivered, according to Jean Stephenne, president of GSK Biologicals.
Lonza buys into immunogenicity
Lonza has bolstered its protein design capabilities by acquiring Algonomics, a CRO with technologies which predict immunogenicity to improve development of protein therapeutics and vaccines.
LFB picks Lonza for CMO deal
French biopharmaceutical group LFB has contracted Lonza’s biopharmaceuticals division to make trial supplies of its candidated monoclonal anti-RhD antibody.
FIT partners to develop HIV vaccine
FIT Biotech has entered into a partnership that will see its GTU MultiHIV DNA plasmid developed using ImmunoVaccine Technologies’ DepoVax delivery tool, which uses liposomes to encapsulate a target antigen and adjuvant.
Who’s making what? Contracts in brief
OutsourcingPharna.com presents a round-up of recent contracts awarded to contract development and manufacturing services companies – and finds a lot of activity in the biomanufacturing sector.
BioReliance to make bulk adenovirus for Duramed
US-based BioReliance has won the contract to supply bulk adenovirus for several live oral vaccines being produced by Barr Pharmaceutical’s Duramed subsidiary.
ProImmune service spikes immunogenic biologics
UK company ProImmune has launched a suite of services to help drugmakers determine at an early stage whether a biologic drug will elicit an immune response in humans.
Pigs and seaweed combine to treat diabetes
New Zealand has approved clinical trials of Living Cell Technologies (LCT) type 1 diabetes treatment, which uses porcine cells encapsulated in a seaweed based gel.
PharmAthene battles for anthrax vaccine bucks
PharmAthene has stated its desire to compete for a government anthrax vaccine manufacturing contract, which could be worth up to $600m.
Bio-Rad speeds up antibody screening
Bio-Rad has published new results showing how its ProteOn XPR36 protein interaction array system can dramatically speed up monoclonal antibody (mAb) screening.
Funding imminent for versatile drug delivery tech
NanoBio is believed to be on the verge of securing funding to continue developing its NanoStat drug delivery platform.
Unraveling the stabilisation of proteins
Evaluating the sugars used to stabilise proteins will be faster, cheaper and more efficient thanks to new technology, claim researchers.
DSM and MorphoSys add MOR202 to Ab deal
US-based DSM Biologics and MorphoSys are teaming up to manufacture the MOR202 antibody, which has shown considerable promise as a treatment for multiple myeloma (MM).
SSB results tell tale of two continents
Bioprocessing specialist Sartorius Stedim Biotech’s (SSB) net profit for the first half of 2008 rose by 3.5 per cent in comparison with last year, although the company continues to face difficulties in North America.
Tobacco - cancers cause or cure?
In an ironic twist, researchers have shown that the tobacco plant, the cause of millions of cases of cancer, can be harnessed to produce personalised cancer vaccines.
CTP is "best-of-breed" for enhancing protein longevity
Modigene says that data from a trial of a Schering-Plough's (SP)
fertility stimulation hormone (FSH-CTP) confirms that carboxyl
terminal peptide (CTP) modification can extend the therapeutic
duration of protein drugs.
Roche licenses zinc finger tech to aid its discovery programmes
Sangamo Biosciences and Sigma-Aldrich have licensed their zinc
finger nuclease (ZFN) technology to Roche to enable the pharma
giant to develop cell lines and transgenic animals.
CytoDyn starts candidate HIV MAb production
New Mexico-headquartered drugmaker CytoDyn has begun the good
manufacturing practice (GMP) standard production of the
developmental candidate anti-HIV monoclonal antibody Cytolin
(lymphocyte function-associated antigen-1).
Nventa hopes Poly-ICR will elicit a strong response
Nventa Biopharmaceuticals hopes that the enhanced durability of its
new Poly IC-Poly arginine (Poly-ICR) adjuvant will help it capture
a significant share of the therapeutic and prophylactic vaccine
MDS expands bioanalysis services
MDS Pharma Services has expanded its portfolio of bioanalytical
testing services with the addition of electrochemiluminescent assay
(ECLA) capability, used to test biological samples from clinical
IgM and IgA purification made simple
The Bio Affinity Company (BAC) has introduced two new products for
scientists who need to purify hard-to-separate antibodies such as
immunogloblins A and M.
EMEA filing for first vaccine using Soluvia microinjection system
The first European approval application for a vaccine delivered via
a new intradermal (ID) microinjection system developed by BD
(Becton, Dickinson & Company) has been filed by Sanofi-Pasteur,
the vaccines division of the Sanofi-Aventis...
Tattooing trumps intramuscular delivery for DNA vaccination
A tattoo you may not end up regretting could be one that provides a
more efficient means of delivering DNA vaccines through the skin.
Funding boost for innovative VacciMax platform
Canadian vaccine specialist ImmunoVaccine Technologies (IVT) has
scored a multi-million dollar grant to go towards developing its
potent immune enhancement systems.
JAMA article boosts Novartis meningitis jab
Novartis has been keen to shout about data published this week in
the Journal of the American Medical Association (JAMA)
that backs up claims that it has developed the first vaccine to
protect infants against the most common meningitis...
Pfizer buys CovX to bulk biologics pipeline
Pfizer, the world's largest pharma firm, has reached into its
pockets to buy CovX, a privately-held US biotech that specialises
in combining the strengths of peptides and antibodies into new
BioWa and Lonza agreement for potent antibodies
BioWa and Lonza are joining forces to develop a new technology platform to produce more potent antibodies with enhanced cell-killing powers.
Pharmaceutical manufacturing: news in brief
In-PharmaTechnologist.com brings you a selection of recent
headlines from around the pharmaceutical manufacturing industry.
Arius and Avid team up
Arius Research and Avid Bioservices have joined forces in the
manufacturing and development of an anticancer antibody.
Regeneron helps make Sanofi VelocImmune to its 'weak' pipeline
Sanofi-Aventis recently admitted it needed to increase the number
of biotech compounds in its pipeline and now, true to its word, the
French pharma heavyweight has signed a big antibody deal with US