Nestle Health Science has licensed a protein engineering platform from Codexis in a $14m deal that includes an option to co-develop a phenylketonuria drug candidate called CDX-6114.
Pfizer is building a $200m (€179m) R&D centre in Chesterfield, Missouri at which it will consolidate biotherapeutics process development operations in the region.
Researchers define action profile of Bial compound
Experts are calling for an increased focus on human cellular model development after animal tests failed to detect the toxicity of an experimental drug before the first-in-human clinical trial that left one dead.
A revised concept paper on first-in-human trials will be ready next month according to the EMA which is reviewing the French Phase I trial in which one volunteer died in January.
The US spends billions on preclinical research that cannot be replicated due to errors in design, problems with lab protocols and mistakes during data analysis according to new research.
Mid-size and large sponsors foresee increases in RFP (request for proposal) volume for outsourced clinical services across all phases through December 2014, especially for larger CROs, according to a new report.
China’s top CRO Wuxi Apptec has purchased a remote clinical trial monitoring tool that will allow its toxicology clients log onto a secure Web site to view data from on-going studies.
Ambrx and Zhejiang Medicine have selected Wuxi to accelerate the development of a potential ADC (antibody drug conjugate) targeting Her2-positive breast cancer.
Covance’s 10 percent growth in Q1 2013 compared to the same quarter last year was driven mostly by its central laboratories business and has caused a boost in its revenue targets for the rest of the year.
Goodwin Biotechnology has teamed up with Coldstream Laboratories to offer clients ADC services as another example of biopharma demand driving contract manufacturing and development.
An uptick in the outsourcing of preclinical trials is expected as pharmaceutical companies look to restructure and cut costs, but that increase won't necessarily begin in 2013, according to an analyst.
CSL has signed a commercial license agreement with Selexis for the preclinical development of a therapeutic antibody anticipated to enter Phase I clinical trials in 2012.
French preclinical contract research organisation (CRO) CIT has said it will buy Canadian counterpart LAB Research in a deal that would rescue the Quebec-based firm from the receivers.
RXi Pharmaceuticals has applied its sd-rxRNA to dermal cells, establishing the efficacy of the technology as it seeks to move it on to the next stage of development, a company VP told in-PharmaTechnologist.
URMC has set up the Center for Human Experimental Therapeutics (CHET) to help biotechs and academics advance product candidates from preclinical studies into trials in human.
GE Healthcare says its new range of sample collection cards reduce sample volumes needed for drug metabolism across pharmacokinetics (DMPK) in all stages of drug development process.
ethica Clinical has added biomarker data analysis technology to its roster of services in a C$1.25m (€782,899) deal with fellow Canadian CRO Matrix Pharma.
US firms Xybion Medical Systems and Locus Technology say their new animal management and data analysis partnership will help streamline preclinical development and reduce research costs.
Yissum is collaborating with Aurum, Ventures MKI to develop a nanotechnology controlled release delivery platform, which is designed to increase the bioavailability of orally administered lipophilic drugs.
Wolfe Laboratories (WLI) has been given a $500,000 (€375,000) loan by the Massachusetts Life Sciences Center (MLSC) to construct the first stage of an aseptic fill/finish manufacturing facility.
Biomodels is providing preclinical services to Applied Protein Sciences (APS) under the terms of a strategic alliance, which is intended to speed product development and expand pipeline.
Seattle, US-based Cell Therapeutics Inc is looking at ways to reduce its involvement in a preclinical research facility based in Bresso, Italy, as it tries to cut costs.
Pharmaceutics International (PII) has cemented a new partnership
with a UK firm that will see it gain bring new preclinical and
clinical services to the North American market.
US-based MPI Research and China's Shanghai Medicilon have formed a
joint venture in preclinical services, as they position themselves
to cash in on what is a budding market sector in China.
Two French contract research organisations (CROs) that specialise
in ophthalmology have banded together to offer specialised services
to this niche market.
In this week's review of activity within the preclinical research
services arena, new deals have emerged involving Arius Research,
Fusion Antibodies, Samaritan Pharmaceuticals and Advinus
Therapeutics.
US-based drug delivery firm, BioDelivery Sciences International
(BDSI), has asked for approval to start clinical trials of a soya
bean-based delivery technology that would lead to the first oral
version of amphotericin B, a widely-used...
US-based drug maker Merck, has agreed to outsource some of its
preclinical trial work to an Indian-based company, marking the
first time the pharma giant has used an Indian company to conduct
drug research.
World-leading clinical research organisation (CRO) Covance has
scored what it says is the biggest contract in its history - a
dedicated space agreement worth a minimum of $187m (€149m).
Construction of the UK National Biomanufacturing Centre, an
ambitious project aimed at helping biotechnology start-ups get
their product ideas into clinical trials, is progressing on
schedule and should be ready to start production...
