The strained relationship between Genentech and Roche has been revealed in a SEC filing, which details their differing valuations and accusations of misleading financial models.
Roche’s proposed $44bn acquisition of Genentech is facing some opposition with Wall Street saying the offer undervalues the company, disquiet among the biotech’s employees and shareholders suing the Swiss giant.
Roche has entered into an agreement to provide drug compounds for
cardiotoxicity testing using a cell-based platform that could play
a major role in the preclinical safety evaluation of drugs and
newly developed compounds.
Roche today announced a handful of new charitable technology
transfer agreements with manufacturers in Africa and Asia, allowing
local production of generic HIV drugs.
Japan will only be receiving 50 per cent of its usual supply of the
blockbuster flu drug Tamiflu (oseltamivir) this year, thanks to
significantly reduced demand following reports of suicidal
behaviour in adolescents taking the medication.
Roche heard early this morning that the European Commission (EC)
has decided to reinstate the marketing authorisation for the
company's HIV drug, Viracept (nelfinavir), but countries outside
the EU have yet to make a final decision.
Roche has just had the child-size, lower strength version of its
blockbuster flu treatment Tamiflu (oseltamivir) approved by EU
authorities, though possibly just a little too late for this year's
flu season.
A US judge has backed Amgen's court motion, ruling that Roche's
Mircera infringes one of its composition patents. Roche is standing
firm against the allegations.
In the latest episode of the Viracept contamination case, the drug
is now at risk of losing its marketing authorisation across Europe
while the dangers posed by the chemical contaminant are established
and manufacturer Roche rectifies...
Just over a week after Roche was forced to initiate a Europe-wide
recall of HIV drug Viracept (nelfinavir), in-PharmaTechnologist.com
considers the contamination case and the pharmaceutical processes
blamed for the incident.
Roche has initiated a recall of its HIV drug Viracept (nelfinavir)
right down to the patient level after finding evidence of dangerous
contaminants in the tablets.
Switzerland-based Roche is helping African nations fight the AIDS
epidemic by sharing its coveted saquinavir drug-producing
technology with two more manufacturers in Ethiopia and Zimbabwe.
Roche gave an update on its manufacturing of influenza drug Tamiflu
(oseltamivir) today, saying that while it had reached its target
capacity of 400 million doses a year, demand is running much lower.
The massive R&D reshuffle Roche announced last week in its
pharmaceutical business will have no impact on any of the company's
outsourcing activities, a company spokesperson said.
Cardinal Health is the latest firm to benefit from Roche's global
recruitment drive for manufacturers to help boost its supplies of
the bird flu drug coveted by governments across the world -
Tamiflu.
Roche took the opportunity to reassure investors and analysts as it
outlined its plans to deal with the impending threat to Avastin and
Herceptin. Roche's new indications for cancer treatments suggest
that its oncology portfolio...
China's State Food and Drug Administration (SFDA) has authorised
Shanghai Sunve Pharmaceutical and Yichang Changjiang Pharmaceutical
to produce a licensed version of Roche's Tamiflu (oseltamivir
phosphate), the first such...
Under pressure to ensure cheap supplies of its flu drug in Africa
in preparation for a possible avian influenza, Roche has asked
contract manufacturer Aspen Pharmacare to produce finished doses of
Tamiflu (oseltamivir) in Africa.
American chemists have found that seeds of the sweetgum fruit
contain significant amounts of shikimic acid, the main starting
material for Tamiflu, in a discovery that could prove vital, as
demand for the drug skyrockets amidst bird...
Responding to surging demand for its flu drug Tamiflu, Roche has
announced it is expanding its external contractors to fifteen in
nine different countries, as its needs for intermediates and
finished product increase.
Swiss pharma giants, Roche, has announced a collaboration with
Amira Pharmaceuticals, which is to focus on inflammatory disease
targets, in a deal that could build on Roche's strong position in
the inflammatory market, having...
New insights into the dysregulation of beta cells and their impact
on type 2 diabetes progression is now possible after Roche
announced a partnership, which aims to identify novel pathways and
new biomarkers for drug development.
Roche has responded to recent criticism that it was protecting its
avian-flu formula too closely by identifying 12 prospective
partners to increase the global production of Tamiflu.
Roche has formed a research collaboration with Epitomics, giving
Roche a license to Epitomics' monoclonal antibody technology
(RabMab technology) for the discovery and development of monoclonal
antibodies to treat cancer and...
Roche Diagnostics has announced it has settled all litigation in
the United States, Europe and Australia, with Promega concerning
Polymerase Chain Reaction Technology (PCR), ending a decade of
litigation between the two companies.
Roche has opened the world's largest polymerase chain reaction
(PCR) manufacturing site in the world, investing more than $150
million and creating approximately 350 new jobs.
Concern over the threat of a new flu pandemic is hiking demand for
Roche's Tamiflu >(oseltamivir phosphate) product to the extent
that the firm needs to build another production plant, reports
Phil Taylor.
The success of personalised healthcare depends on a better
understanding of how gut microbes interact with different
medicines, according to scientists, who believe that the microflora
makeup of an individual has been overlooked when...
Pharmasset of the US could receive funding of $168 million
(€131.8m) in upfront and milestone payments - with the prospect of
receiving more - after licensing its preclinical hepatitis C drug
programme to Swiss drug giant Roche.
India's Dishman Pharmaceuticals and Chemicals has set up a company
specialising in the contract manufacture of active pharmaceutical
ingredients (APIs) and intermediates that is specifically aimed at
winning business from foreign...
Switzerland's Roche is setting up an R&D centre in Shanghai in
a move which reflects the growing importance of the country as both
a market for pharmaceutical products and a site for drug research.
Switzerland's Roche is subject to a fresh legal challenge over its
patent position in polymerase chain reaction (PCR) testing, this
time from Applera unit Applied Biosystems.
BioFocus has entered into an agreement with Switzerland's Roche for
the design of a several custom kinase libraries for use in the
latter's drug discovery efforts.
Roche forges an alliance with ParAllele to discover genes that
contribute to type 2 diabetes, aimed at identifying potential new
medicines and diagnostics for the disease.
A US appeals court has reversed an earlier decision to make
Switzerland's Roche pay almost $500 million in damages to Igen in a
dispute over a technology used in clinical diagnostics and
pharmaceutical research.
Roche has licensed exclusive marketing rights outside the USA to
Avastin (bevacizumab), a drug for colorectal cancer, from
Genentech. The latter company will retain all rights to the drug in
its home market.
UK developer of medical diagnostics devices Osmetech continued the
strategy to build on its healthcare diagnostics business with the
acquisition this week of the Atlanta-based 'OPTI' product line of
blood gas analysers owned...
Shareholders at Swiss pharmaceutical company Roche welcomed the
start of a new era as the company summarised recent events,
including the divestment of the vitamins business, at its annual
general meeting yesterday.
