Delivery formulations

Pantarhei Sells Stake in Oral Contraceptive JV

25-Feb-2013

Pantarhei Bioscience has sold in Estetra, its oral contraceptive development JV, to partner Uteron Pharma and will use the proceeds to fund further development.

Unichem Sell Indian Formulation Plant to Mylan

19-Feb-2013 By Dan Stanton

Mylan Laboratories has purchased a new finished formulations facility in an Indian Special Economic Zone from Unichem Laboratories.

update

Aesica and EmulTech Claim Micro-Encapsulation can Revive Formulation Projects

18-Feb-2013

Aesica and EmulTech claim a new sterile formulation technology could help drugmakers resurrect abandoned projects and extend the lifespan of marketed medicines.

EpiVax says Novozymes Collaboration has $3bn Potential

13-Feb-2013 By Gareth Macdonald

EpiVax says combining its immune 'off switch’ drugs with Novozymes’ half-life boosting Albufuse platform could deliver a $3bn (€2.2bn) section of the autoimmune disease market.

Aduro focus on combinations in purchase of GVAX vaccines

05-Feb-2013 By Dan Stanton

Aduro says “combinations are the future” after bolstering its immunotherapy portfolio.

Flublok maker open to sharing egg and virus-free manufactuing tech

31-Jan-2013 By Gareth Macdonald

Protein Sciences says it will license the novel manufacturing technology behind recently approved influenza vaccine, Flublok, to other producers.

Scinopharm starts developing own drugs with eye on API customers

30-Jan-2013 By Gareth Macdonald

Taiwanese API maker Scinopharm has taken a first step towards developing its own drug portfolio in partnership with delivery tech firm Foresee Pharmaceuticals.

Granules optimistic after poor Q3: "PFI bottleneck will be unblocked"

29-Jan-2013 By Dan Stanton

Granules India says it expects to be back on track by 2014 following slow sales growth and depressed profitability margins.

Find esophageal transit failure hard to swallow? Fuisz says new pill design can help

24-Jan-2013 By Gareth Macdonald

Fuisz Pharma says a new tablet design will be of interest to pharma formulators who find esophageal transit failures hard to swallow.

Synthon Unveils ADC Facility as Data Show Promise for First Candidate

24-Jan-2013 By Zachary Brennan

Following a wave of recent investment in ADC production, Synthon has opened an ADC manufacturing facility in Nijmegen, Netherlands, to help bring its first preclinical ADC program to clinical trials by 2014.

Dedicated facility injects CRM197 into conjugate vaccine market

21-Jan-2013 By Dan Stanton

Reagent Proteins says its ability to produce scalable amounts of protein CRM197 supports the current demand in production of conjugate vaccines.

Bioavailability to drive drug delivery deals in 2013 says analyst

15-Jan-2013 By Dan Stanton

Demand for improved bioavailability solutions will drive drug delivery dealmaking in 2013 according to a pharmaceutical industry expert.

FDA Shifts Focus to Abuse-Deterrent Generic Opioid Development

15-Jan-2013 By Zachary Brennan

The US Food and Drug Administration (FDA) can require opioid generics to have abuse-deterrent properties if the same requirements are applicable to their brand name counterparts, FDA Commissioner Margaret Hamburg said in a letter to Rep. Fred Upton (R-Mich.)...

Arrowhead Research scientists claim RNA delivery bull’s eye

03-Jan-2013 By Gareth Macdonald

Scientists from targeted therapeutics firm Arrowhead Research claim a vesicle bursting polymer can overcome siRNA delivery difficulties.

Mitsubishi to buy dominant HPMC capsule maker Qualicaps as gelatin shortages continue

03-Jan-2013 By Gareth Macdonald

Mitsubishi Chemical Holdings (MCHC) has announced plans to buy the ‘dominant’ pharma-grade HPMC capsule maker Qualicaps as the global gelatin shortage continues.

Symrise-Probi partnership to deliver probiotic goods in 2014-15

20-Dec-2012 By Shane Starling

German fragrance and flavours house Symrise has just last night inked a deal with Swedish probiotics firm Probi to develop a stand-alone R&D project with oral probiotic supplements the most likely product out of the pipeline in 2014-2015.

Sunwin Stevia pours cash into production

05-Dec-2012 By Rod Addy

Sunwin Stevia International has invested heavily in production capacity to support declared growth plans in China.

Hovione and Solvias form industry's latest bioavailability-focused accord

28-Nov-2012

Hovione and Solvias have become the latest suppliers to team on drug solubility and bioavailability services in a new deal announced today.

FTC says suppressing generics by ‘product hopping’ is illegal

28-Nov-2012

The US Federal Trade Commission (FTC) says making insignificant reformulations to drugs to block generic competition violates antitrust laws.

Merck Millipore to open new bioavailability lab in 2013

27-Nov-2012 By Gareth Macdonald

The bioavailability market lacks a leader that can offer comprehensive solutions according to Merck Millipore, which has set its sights on filling the gap through investments and a new lab.

Marinomed granted Chinese patent for cold virus fighting polymer

20-Nov-2012

Marinomed Biotechnologies is set to take on the ‘common cold’ in China with a new patent for an anti-viral polymer technology that prevents rhinovirus infection.

News from AAPS

Low API and excipient volumes vital to win authorisation under EU PIP says EMA

23-Oct-2012 By Natalie Morrison

Pharmas should use lower API and excipient volumes if seeking authorisation under the EU Paediatric Investigation Plan (PIP) says the EMA.

Octoplus to be stand alone R&D unit says Dr Reddy's; no job cuts planned

22-Oct-2012 By Gareth Macdonald

Indian drugmaker Dr Reddy’s wants to buy Netherland’s-based formulation services firm Octoplus to expand its drug delivery technology portfolio.

Dispatches from AAPS

Capsugel expands liquid fill capsule capabilities

17-Oct-2012 By Natalie Morrison

Capsugel has expanded its Licaps liquid fill capsule line with a new facility in the US.

Encap teams with academics on HME

09-Oct-2012

Encap Drug Delivery (EDD) wants to develop hot melt extrusion capabilities to differentiate its service offering.

EXCLUSIVE

EMA biosimilar guidance welcomed but has further to go, say EGA, Aptuit and Charles River

04-Oct-2012 By Natalie Morrison

Latest EMA biosimilar guidance on reference products is a “major breakthrough” but there is still work to do, say industry experts.

BASF focuses on topical formulations to solve skin delivery challenges

27-Sep-2012 By Natalie Morrison

BASF has opened a topical formulations lab in a bid to solve skin delivery challenges.

Could oral testosterone replacement therapy come in a capsule?

26-Sep-2012 By Natalie Morrison

Clarus Therapeutics believes it has solved the oral availability problem for testosterone replacement therapy.

Could laser-focused microjets mean pain-free injections?

25-Sep-2012 By Natalie Morrison

A laser which pushes a stream of medication into the skin could be a “pain-free” replacement to needle injections.

More patient-centric formulations for the elderly, experts urge

19-Sep-2012 By Natalie Morrison

New formulations and easier drug delivery methods could help elderly patients comply with treatments, experts say.

EMA calls for feedback on patch and modified release delivery techs

17-Sep-2012 By Gareth Macdonald

Delivery speed and accurate dissolution testing are top priorities in new EMA draft guidance for tablet and patch developers.

Non-stick nano-coating could solve delivery challenges in the brain

12-Sep-2012 By Natalie Morrison

The answer to the brain drug delivery riddle could soon be solved thanks to new nanoparticles designed by researchers at John Hopkins University.

Takeda plans to dominate thriving Russian pharma market, starting with a new plant

11-Sep-2012 By Natalie Morrison

Takeda has opened a new $96m (€75m) pharma facility in Russia as part of its bid to “outgrow” the already thriving local market.

Hermes partners to develop taste masking, particle coating tech

10-Sep-2012 By Gareth Macdonald

Hermes Pharma says it can solve the stability challenges that held back development of lipid-based particle coating techs.

Is the male contraceptive pill coming soon?

06-Sep-2012 By Natalie Morrison

A male version of the contraceptive pill could be just around the corner, according to researchers at Texas A&M University.

Hospira buys Indian API plant to boost antibiotics biz

30-Aug-2012 By Natalie Morrison

Hospira has bought Orchid Chemicals and Pharmaceutical’s active pharmaceutical ingredient (API) facility in Aurangabad, India, to support its expanding antibiotic business.

Delivery tech deals for Depomed, Silence and funding for Micropoint

28-Aug-2012

New developments in the delivery space with Depomed signing up another Big Pharma licensee, Silence teaming up to test its tech for MiReven and Micropoint securing development funds for its microneedle system.

First universal HIV vaccine could be on its way, say researchers

22-Aug-2012 By Natalie Morrison

The first effective universal HIV vaccine may soon be on its way thanks to a family of highly potent (HP) antibodies which neutralise the virus, according to new findings.

Capsugel wants to standardise lipid formulation tests

22-Aug-2012 By Natalie Morrison

Capsugel has launched a non-profit consortium in a bid to establish a lipid formulation classification system.

New sustained release hydrogel could mean twice-yearly injections for diabetes sufferers

16-Aug-2012 By Natalie Morrison

A new hydrogel which can provide a sustained drug release of up to six months could cut diabetes dosage down from 365 injection per year to just two, according to researchers.

Accu-Break and Alembic join in tablet-splitting tech accord

09-Aug-2012 By Gareth Macdonald

Tablet technology firm Accu-Break Pharmaceuticals has signed a product development and licensing agreement with Indian generic drugmaker Alembic Pharmaceuticals.

New Herceptin formulation allows delivery via injection

09-Aug-2012 By Natalie Morrison

A new formulation of Genetech’s breast cancer drug Herceptin means patients could soon receive treatment via injection, rather than time consuming intravenous drip.

SRI to develop bioadhesive HIV and HSV formulation

30-Jul-2012 By Gareth Macdonald

Researchers at SRI International say a bioadhesive-based platform delivery could help slow the spread of HIV and HSV in Africa.

Nanoshells could solve oncology dual delivery riddle

18-Jul-2012 By Natalie Morrison

Hollow nano shells capable of holding both cancer fighting drugs and immune-system boosters could be the solution to oncology’s greatest delivery riddle, according to Yale University researchers.

Prosonix teams with ICL to assess MCPs for COPD and asthma

11-Jul-2012 By Gareth Macdonald

Prosonix aims to develop new treatments for respiratory diseases though an R&D accord formed with Imperial College London (ICL).

Round up of drug delivery news from academia

27-Jun-2012

in-PharmaTechnologist.com presents a roundup of academic drug delivery news, including Pfizer working with Chinese researchers.

FDA says Amylin withheld data on extended-release drug

26-Jun-2012 By Nick Taylor

The FDA has accused Amylin of withholding cardiac safety information in its marketing application for an extended-release diabetes drug.

Is drug delivery by skin the solution to bioavailability woes? report from Achema

21-Jun-2012 By Natalie Morrison

Drug regulators and the biomanufacturing industry need to embrace drug delivery via the skin to solve solubility problems with peptides and proteins, according to Across Barriers’ Udo Bock.