Evidence shows that animal models currently dominating bioavailability estimates are poor predictors and human, cell-based multi-organ microphysiological systems (MPS) should be investigated, CN Bio says.
The pharmaceutical company reports studies have demonstrated the main protease inhibitor of Paxlovid maintains in vitro efficiency against the variant.
Developers of generic drugs administered with topical drug delivery methods benefit from MedPharm’s in-vitro models to safely demonstrate bioequivalence.
Leveraging Eurofins’ pharmacology, in-vitro models and ADME capabilities, PharmaResources aims to accelerate drug discovery for its clients in small molecule drug R&D.
Amylgen and Neuron-Experts partner to create a comprehensive offering of in-vivo and in-vitro efficacy evaluation for compounds in neurodegenerative diseases.
Engineered cardiac tissues generated using Tara Biosystems' heart-on-a-chip system predict how patients will respond to a range of drugs, as demonstrated in a recent study with GSK.
In response to a growing interest in alternative testing methods, SenzaGen signs a license agreement with MB Research Labs to expand the use of its animal-free testing platform.
Lonza enters private label partnership to manufacture and globally commercialize AllCell’s hematopoietic primary cells to provide greater access to researchers.
As complex drugs see little competition, the FDA will distribute guidelines to increase approvals of generic medicines for ‘economic stability’ and to bring affordable drugs to patients.
PinneyAssociates and NMS Labs will plan, conduct, and analyze in vitro laboratory testing of pharmaceutical formulations to evaluate any abuse-deterrent properties, says CMO.
SGS announced it will provide new in vitro toxicology services at its Mississauga, Canada Laboratory following an investment in instruments and laboratory capabilities.
IIVS is collaborating with global laboratories to validate an improved skin sensitization reactivity method to meet toxicology and regulatory requirements.
The global market for in vitro toxicity testing is predicted to reach $8.8bn by 2023 – and demand is expected to increase, driven by new technologies and regulations, says Charles River.
KMT Hepatech is expanding its services with the PXB-Mouse – a humanized liver chimeric mouse model for drug discovery and development – following a strategic investment from PhoenixBio late last year.
AMRI’s SSCI has announced the availability of in vitro bioequivalence testing services, as more products entering the market require laboratory-based testing.
The People for the Ethical Treatment of Animals (PETA) is looking to send a researcher to learn about non-animal test methods – adoption of which it says is slowed by regulatory agency acceptance.
Envigo is developing new In vitro tests in advance of the Comprehensive In Vitro Proarrhythmia Assay (CiPA) recommendations expected at the end of the year.
EAG Laboratories has added dermal absorption studies to its GLP-compliant testing services suite, as part of the company’s plan to continue expanding its capabilities.
WuXi PharmaTech has signed a strategic partnership deal to provide exclusive laboratory testing services to Hong Kong-headquartered Lee’s Pharmaceutical.
Animal-model contract research organisation (CRO) Crown Bioscience will open a research centre in North Carolina, combining expanded oncology services with its existing cardiovascular and metabolic offerings.
As big pharma and biotech companies increasingly take R&D centers offline, the companies are also looking to reduce the number of outsourcing partnerships, Jim Foster, CEO of Charles River Laboratories, said recently.
Caliper Life sciences has entered into a definitive merger agreement with Cambridge Research & Instrumentation (CRi) to boost its discovery biomarker and personalised medicine development offering.
Precos is aiming to accelerate growth of its attrition-reducing preclinical oncology screening services by naming a co-founder of ClinPhone as chairman.
San Diego-based biotechnology contract research organisation (CRO) Bio-Quant has expanded its animal diagnostic services offering to cover all nine species used in medical research.
